@Salic_Lab

Lab of Adrian Salic @harvardmed @HarvardCellBio Our lab studies how vertebrate cells send and respond to Hedgehog signals #hedgehog 🦔 #cilia

 Boston, MA
salic.med.harvard.edu
Joined March 2018
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  • Following220
  • Followers342
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Salic Lab retweeted
EatonLab@eaton_lab5 Jul 2019
Please share this message to anyone in #cretegreece or surrounding regions m.facebook.com/story.php?sto…
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More exciting news! Former postdoc Long Li has struck out on his own with great success! Here’s his first #cryoEM structure: a complex of SecA and SecY translocating a polypeptide chain substrate. nature.com/articles/s41467-0…

Structure of the substrate-engaged SecA-SecY protein translocation machine

Nature Communications - Proteins are translocated across membranes through the Sec61/SecY channel. Here, the authors present the structure of a translocating peptide chain trapped inside the...

nature.com
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Salic Lab retweeted
nature
@Nature15 Apr 2019
A fully referenced guide to making your lab more nurturing, collaborative and people-centred, courtesy of @ftmaestre. journals.plos.org/ploscompbi…
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On #InternationalWomensDay, we’re celebrating women in the Harvard Medical School community who are making a difference in the world
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We hope that this updated review on ciliary signaling will be of interest to anyone in the fields of development, organ function and disease. A great thanks goes to Zeinab, Kirk, Saikat and Lotte(@LottePedersen12) doi.org/10.1038/s41581-019-0… @NatRevNeph
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Congrats @CentrioleLab for casting new light on an age-old problem: How are microtubule doublets assembled? science.sciencemag.org/conte…
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Scientist photo challenge. #7scientistchallenge 7 portraits of 7 scientists posted over 7 days. Photos must be your own. Nominated by MYSELF and nominating @NathanShaner. Day #2: Timothy J. Mitchison, 2004 (Rolleiflex 2.8E, Ilford delta 100)
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Playfulness and independence are critical to scientific success, says former @HMS_SysBio department chair Marc Kirschner hvrd.me/Rli230mSiGd
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« I repeatedly told everyone I met that the course of basic science cannot be predicted and certainly not directed, or rather, should not be directed. » Marc Kirshner, 1st chair of systems biology Dept. Harvard.
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Salic Lab retweeted
Randy King@rwkhms30 Nov 2018
Upon closer inspection of data, seems Trump partially degraded following elution @Salic_Lab
Randy King@rwkhms29 Nov 2018
For my science friends, best happy hour poster ever @Salic_Lab
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How curiosity about embryonic patterning led from identification of Hedgehog signalling to the development of cancer drugs Historical and surprisingly personal (see Fig 6A) perspective from @phil1pingham #AdvocatingDevBio dev.biologists.org/content/1…
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3 HMS scientists have received the prestigious Allen Distinguished Investigator awards for their work in the fields of neuroimmunology, developmental biology and cancer hvrd.me/UaA230mrWeH
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Amazing images. The cilium is not a cylinder, and super-res reveals mutation-induced changes in morphology not seen by conventional fluorescence imaging
bioRxiv@biorxivpreprint9 Oct 2018
Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy biorxiv.org/cgi/content/shor… #bioRxiv
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BREAKING NEWS The 2018 #NobelPrize in Physiology or Medicine has been awarded jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”
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Shrews sometimes travel in a sort of ‘conga line’ formation, with the mother leading, and all the little shrews grasping the tail of the shrew in front. This is known as a ‘caravan’ or if you prefer, a shrew-shrew train.
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Seipin is a key factor for fat storage; here are new insights on how it works from our lab and Maofu Liao’s @HarvardGCD @HarvardCellBio @HHMINEWS
bioRxiv Cell Biology@biorxiv_cellbio14 Sep 2018
Cryo-electron microscopy structure of the lipid droplet-formation protein seipin biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Very neat study from the Verhey lab. These rapid inactivation techniques are what is needed to move the field forward. biorxiv.org/content/early/20…
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Marc Kirschner discussing the future of graduate/postdoc training at Bruce Alberts 80th birthday celebration. Only Bruce could turn a birthday party into an engaging all-day symposium on science education and policy. @frazierarchive
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A phage-derived peptide selectively binds to the Frizzled 7 CRD resulting in disruption of the dimer interface impairing Wnt/β-catenin stem signaling in intestinal organoids. go.nature.com/2Exbl2T
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Salic Lab retweeted
Susan Shao@sshaolab4 Apr 2018
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