@SeanBurnap

Postdoc Struwe lab | University of Oxford | Cardiovascular Proteomics PhD

 Oxford
Joined December 2012
  • Tweets29
  • Following211
  • Followers89
🗞️ Dobson Junior Research Fellow in Molecular Biophysics Dr Sean Burnap has been awarded a Wellcome Early Career Award to support his research project into Filovirus-host interactions. Head to lmh.ox.ac.uk/news to find out more🔗 #LadyMargaretHall #LMH #UniversityOfOxford
A photograph of Dr Burnap wearing a black t-shirt, looking straight at the camera with a slight smile. Text across the image reads 'Dobson JRF Sean Burnap Awarded Wellcome Early Career Award'.

ALT A photograph of Dr Burnap wearing a black t-shirt, looking straight at the camera with a slight smile. Text across the image reads 'Dobson JRF Sean Burnap Awarded Wellcome Early Career Award'.

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#MeetTheResearcher Happy to introduce Sean Burnap from the Struwe Group this week! Sean is a postdoctoral researcher who was recently awarded the @wellcometrust Early Career Fellowship for his research on filovirus-host interactions.
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Meet us at the University Parks on Sunday the 12th of May, at 10 am, to support our super star researchers who will be running the Town and Gown 10K! @MDUK_News #KavliOxford
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#KavliOxford is delighted to announce the appointment of @WestonStruwe as an Associate Professor of Cellular and Molecular Biochemistry and Tutorial Fellow at @WorcCollegeOx. kavli.web.ox.ac.uk/article/w… @BiochemOxford @UniofOxford @KavliFoundation @OxfordMedSci

Weston Struwe Appointed as Associate Professor of Cellular and Molecular Biochemistry and Tutorial...

kavli.web.ox.ac.uk
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Exciting News! #KavliOxford researchers have secured funding from @UKRI_News BBSRC for cutting-edge equipment, propelling groundbreaking research in cellular and biomolecular analysis. Details here👇 tinyurl.com/4skf286s @KavliFoundation @mplsoxford @OxfordMedSci @UniofOxford
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Theofilatos et al found that proteomic signatures of #plaque composition were found to predict long-term, adverse CV events, improving risk stratification for patients with advanced #atherosclerosis. ahajrnls.org/48hrN6r @k_theofilatos @Vascular_Prot @swvanderlaaan
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We are happy to present our workflow DQGlyco enabling the in-depth quantification of glycoproteome dynamics. In total, we characterize > 150,000 glycoforms in the mouse brain. tinyurl.com/DQGlyco
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Excited to share @SeanBurnap's latest work in our lab, about the interactions between SARS-CoV-2 spike protein and high-density lipoproteins! #XLMS #HDL mcponline.org/article/S1535-…

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the...

In BriefHere we utilized cross-linking mass spectrometry (XL-MS) to investigate circulating protein interaction networks in the context of SARS-CoV-2. The spike glycoprotein was determined to...

mcponline.org
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Congratulations @SeanBurnap for the MJ Dunn fellowship award👏! #BSPR
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Delighted to share perhaps the last of my work to come from my time in the Mayr lab @Vascular_Prot. Here we used cross-linking mass spectrometry #XLMS to uncover interactions between the SARS-CoV-2 spike protein and high-density lipoproteins #HDL. mcponline.org/article/S1535-… 🧵1/7

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the...

In BriefHere we utilized cross-linking mass spectrometry (XL-MS) to investigate circulating protein interaction networks in the context of SARS-CoV-2. The spike glycoprotein was determined to...

mcponline.org
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However, to our surprise, ApoD overexpression failed to influence SARS-CoV-2 replication and infection in cell-based assays. 6/7
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A massive thank you to our collaborators, particularly @KaloyanTakov and of course the Mayr lab @Vascular_Prot. 7/7
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Sean Burnap retweeted
Liang Wu@liangford4 Apr 2023
Quick bump on the below 👇 we are looking for a pdra to apply protein labelling methods to aid cryoEM of #glycotime biosynthesis inside cells. Closing next week 10th. Contact me for more details opportunities.rfi.ac.uk/vaca…
Liang Wu@liangford13 Mar 2023
In other news, I have an opening for a PDRA in my group @RosFrankInst opportunities.rfi.ac.uk/vaca… Job is to apply (bio)chemical protein labelling methods to aid cryo-EM and ET imaging. End goal is to see #glycotime machinery working inside cells. Contact me for details. Pls share

About The Rosalind Franklin Institute - Rosalind Franklin Institute

The Rosalind Franklin Institute is a new national institute, announced in 2017 by the UK government, dedicated to bringing about transformative changes in life science through interdisciplinary...

opportunities.rfi.ac.uk
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Read our latest #research by E. Duregotti on the contribution of reduced secretion of Negr1 to #adipose - #neuronal crosstalk in #obesity, published with @SpringerNature in @NatureComms!👇 rdcu.be/c0qxy
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Excited to see our new @refeynit TwoMP sitting next to commercial instrument #5 (remember Arago Biosciences anyone?). Here’s to more #massphotmetry in the @KavliOxford
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New 🔥 article from our Emerging Investigators collection: 'Mass photometry reveals SARS-CoV-2 spike stabilisation to impede ACE2 binding through altered conformational dynamics' by @WestonStruwe and @SeanBurnap at @OxfordChemistry and @KavliOxford 🔓 rsc.li/3tAf37Z

Mass photometry reveals SARS-CoV-2 spike stabilisation to impede ACE2 binding through altered...

Here we show using mass photometry how proline substitutions, commonly used for SARS-CoV-2 spike stabilisation in vaccine design, directly affects ACE2 rec

pubs.rsc.org
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