We are a group of passionate scientists. We use modern tools of organic chemistry to build up a more enjoyable and sustainable future.
Nottingham, England
Joined July 2019
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Congratulations to George, who passed his viva last week! A relaxed smile and a very distinguished tie to mark the occasion. Well done, and all the best for the next step in your career! @ChemistryUoN @UniofNottingham Thanks Adam Noble for examining George.
Had a great time visiting @Genentech in San Francisco and presenting some of our recent work.
Many thanks for the invitation, stimulating discussions, and insightful questions. Particularly rewarding to hear how some of our chemistry is being applied in medicinal chemistry.
It was a pleasure to visit @ucdchemistry, thanks for the excellent hospitality and for the stimulating discussion! @chemFunMan @McGarrigleGroup @GuiryGroupUCD @Bieszczad_B @RoySocChem @ChemistryUoN
@RoySocChem Prize 🏆 recipient @SilviResearch gave his lecture talk, we has lunch with colleagues Peter & @GuiryGroupUCD congratulations 🎊
Richard Layfield of @SussexUni gave a great talk and we had a good dinner with Grace @ucdchemistry
Great to see our recent @J_A_C_S paper about the synthesis of 4-members rings from alkenes pubs.acs.org/doi/10.1021/jac… highlighted as Synfacts of the Month thieme-connect.de/products/e… thanks @thiemechemistry for the recognition and well done to the team!
📢 We are recruiting a postdoctoral researcher to join our dynamic research group at @UniofNottingham ! ⚗️🧪🧑🔬👩🔬💡 Check out our website silviresearch.com for more info and to find out how to apply! 👀
Silvi Research Group retweeted
Delighted to share our latest work out in @J_A_C_S describing a general route to access 2-alkyl substituted 4-member rings from simple alkenes, becoming one of the most read articles of the month !! Kudos to the team 🎉 @SilviResearch @buck_louis77859
Thrilled to share our latest work in @J_A_C_S, describing a general route to 2-alkyl-substituted 4-membered rings from alkenes. Well done to @buck_louis77859, @Maria_Pelosi, and everyone else involved for the exceptional team effort. @ChemistryUoN pubs.acs.org/doi/10.1021/jac…
Deadline approaching soon! Apply to our CDT PhD programme co-funded @AstraZeneca . Follow the link: reschem-nottingham-cdt.ac.uk… to submit your application. Available positions for UK-home and international students.
📢 We are recruiting PhD candidates to join our dynamic research group at @UniofNottingham ! ⚗️🧪🧑🔬👩🔬💡 Check out our website silviresearch.com for more info and to find out how to apply! 👀
Silvi Research Group retweeted
#AmBeedNewsletter ✨ Recently, Professor Mattia Silvi's team (@SilviResearch) at @UniofNottingham published a research paper in @J_A_C_S titled "A Unified Synthetic Approach to 2-Alkyl Azetidines, Oxetanes, Thietanes and Cyclobutanes from Unactivated Alkenes".
💡Key Highlights
✅Atom economy: C1 homologation concurrently constructs C-X and C-C bonds.
✅Modularity: three-dimensional tunability of alkene, nucleophile, and substitution order.
✅ Functional group tolerance: compatible with acid-, base-, and oxidation-sensitive groups; obviates protecting group strategies.
✅Structural accessibility: streamlines synthesis of complex molecules previously requiring 5–10 steps.
📚🔻 𝐑𝐞𝐚𝐝 𝐦𝐨𝐫𝐞 𝐰𝐢𝐭𝐡 𝐀𝐦𝐛𝐞𝐞𝐝
ambeed.com/newsdetail/Homolo…
@ChemistryUoN #OrganicChemistry #Photocatalysis #Azetidines #Thietanes #Oxetanes #Cyclobutanes #MedicinalChemistry #DrugDiscovery #AmBeed #JACS
Thrilled to share our latest work in @J_A_C_S, describing a general route to 2-alkyl-substituted 4-membered rings from alkenes. Well done to @buck_louis77859, @Maria_Pelosi, and everyone else involved for the exceptional team effort. @ChemistryUoN pubs.acs.org/doi/10.1021/jac…
Thanks @WickensGroup for highlighting our work on the development of an homologative 1,3-dielectrophilic activation strategy for alkenes. Highlight online on onlinelibrary.wiley.com/doi/…
Silvi Research Group retweeted
Looking to build oxetane-containing scaffolds? 🔎 Dineopentylvinylsulfonium Triflate enables efficient formation of oxetanes from alcohol-derived substrates under mild photochemical conditions. Developed by S. Paul and colleagues (lnkd.in/d4AuNm7d), this reagent works with a broad range of alcohols—including cyclic, acyclic, and heterocyclic—delivering oxetanes in excellent yields with high site selectivity.
✔️ Broad substrate scope for versatile scaffold design
✔️ Mild, photochemical conditions—no harsh reagents
✔️ Ideal for medicinal chemistry programs to tune 3D shape and physicochemical properties.
🛒 Available at Enaminestore with immediate shipping:
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Find this reagent and many other useful reagents for synthesis, ready for immediate shipping to support your research 👉lnkd.in/dgdxWbVR
@SilviResearch
📢 We are recruiting PhD candidates to join our dynamic research group at @UniofNottingham ! ⚗️🧪🧑🔬👩🔬💡 Check out our website silviresearch.com for more info and to find out how to apply! 👀
Honoured to receive the 2025 Philip Leverhulme Prize leverhulme.ac.uk/news/2025PL…
Thanks to @LeverhulmeTrust for this recognition and for their continuous support.
Grateful to my amazing team and to @EPSRC, @royalsociety, @ChemistryUoN, @AstraZeneca & @GSK for their continued support
Proud that our latest work was published in @angew_chem and selected for #AngewandteChemieNovit. Well done to @Subhasis2107, @RichardsonChem & @buck_louis77859 and our @Unibo & @Unipisa visiting PhDs Roberta (@MelchiorreGroup), Giovanni (@gbbencio) & Francesca (@mauro_pineschi)
#AngewandteChemieNovit Mattia Silvi (@SilviResearch) and co-workers @ChemistryUoN report on thianthrenium salt-mediated homologative 1,3-dielectrophilic activation strategy for alkene difunctionalization #openaccess 🔓 onlinelibrary.wiley.com/doi/…
Honoured to receive such a prestigious recognition. Thanks #RSCprizes and special thanks to our funders @EPSRC, @AstraZeneca, @royalsociety, @LeverhulmeTrust, @EU_Commission, @ChemistryUoN, and to all the present and past members of my research group.
rsc.org/standards-and-recogn…
Pizza meal to say goodbye to our MSci student Sonny, who did a great job in our lab functionalizing big, complex molecules! All the best for your next career step, Sonny!
Last week we said goodbye to our visiting PhD student Francesca Sardelli from @Unipisa. Francesca did a great job in our group and we wish her all the best for her future career! 🙂
This week, for our @ChemistryUoN seminars, we hosted @Melchiorre_P @MelchiorreGroup who gave a brilliant talk about combining photochemistry with organocatalysis, transition metal catalysis and biocatalysis to expand the boundaries of traditional asymmetric catalysis.
All the best to our visiting PhD student @Robi_Coc from @MelchiorreGroup who will be returning home to continue her studies @Unibo. Roberta did a great job with us @ChemistryUoN. Picture from her farewell meal (Robi first left in pic).
