@StPierreLab

Synthetic Neurobiology Lab @BCMhouston & @RiceUniversity. Our mission is to develop new molecular tools to accelerate the pace of biomedical discovery

 Houston, TX
stpierrelab.com
Joined May 2019
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Huge thanks to our amazing collaborators @IBENS_ENS (Laurent Bourdieu, Vincent Villette, Jon Bradley and team), Na Ji @UCBerkeley, Brice Bathellier at l'Institut de l'Audition, and @BarnaDudok and @viajake at @bcm_neurosci. ⚔️Team science at its best!
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High praise to the best collaborators in the Galaxy, who deployed FORCE1s in vivo, including the teams of @WikiZong (2P miniscope), Na Ji (FACED), @IBENS_ENS (Laurent Bourdieu, Vincent Villette, Jon Bradley), and @viajake @bcm_neurosci. Contact Dr. St-Pierre for FORCE1s.
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#MayThe4th be with you! Meet FORCE1s, a new positive‑going, ultrasensitive voltage indicator. Optimized for 2P imaging at slower acquisition speeds, FORCE1s is easy to use on almost any microscope. Bonus: it even powers 2P miniscope experiments!📄Preprint: biorxiv.org/content/10.64898…
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Grab some JEDI3 plasmid or AAV from Addgene and join the JEDI order. addgene.org/browse/article/2…

Addgene

addgene.org
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#MayThe4th announcement: JEDI-2P was not The Last Jedi ⚔️! Introducing JEDI3sub & JEDI3hyp, the best GEVIs in this galaxy for reporting subthresholds voltage dynamics under two-photon illumination🔬#GEVIs. Check out our @naturemethods paper: nature.com/articles/s41592-0…

Designer indicators for two-photon recording of subthreshold voltage dynamics

Nature Methods - The genetically encoded voltage indicators JEDI3sub and JEDI3hyp enhance monitoring of subthreshold neuronal activity in the awake mouse brain using a variety of two-photon...

nature.com
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🚨 We’re hiring! The St-Pierre Lab at Baylor College of Medicine has exciting opportunities: 🔬 Postdoctoral position 👩‍🔬 Staff position Work on cutting-edge electrophysiology and optical tools to advance neuroscience! See: shorturl.at/uim4d #Neuroscience #Ephys #PostdocJobs

St-Pierre lab | We're hiring!

stpierrelab.com
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The Force Awakens at #Sfn2025 ! Join us tomorrow AM for poster LBP038: introducing FORCE1s, a positive-going GEVI engineered by the St-Pierre lab for ultrasensitive voltage detection. Stunning in vivo results from the Reimer, Bourdieu, @NaJiBerkeley, and Weijian Zhong labs.
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The Return of the JEDI! St-Pierre lab poster LBP037 tomorrow AM @ #Sfn2025: unveiling JEDI3 — next-gen Genetically Encoded Voltage Indicators (GEVIs) for enhanced detection of subthresholds under 2P. Great collaboration with the Bourdieu,@NaJiBerkeley, @BarnaDudok & Reimer labs
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