Plasma Cell Disorders; Tx/Cell Therapy Physician @ UAB Medicine via Memorial Sloan Kettering; U of Cincinnati & Kettering; Tweets=My opinions #mmsm
Birmingham, AL
Joined March 2017
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I'm running with MMRF Team for Cures to fundraise for the Multiple Myeloma Research Foundation. With each mile, I hope to accelerate the discovery of cures for the second most common blood cancer. Will you help me reach my fundraising goal? do.nr/swmnku18 via @DonorDrive
Thank you for the invitation @szusmani and Sham Mailankody to join this fantastic meeting, really great presentations and discussion.
We're so excited to be at the inaugural #iwGPRC5D2025 Workshop! We'll be hearing about all things related to GPRC5D-targeted myeloma therapies - stay tuned for more.
Chaired by @szusmani & Sham Mailankody
#MMsm #HemOnc
The funnest talk from @JoshuaRichterMD and a new acronym for neurotoxicity with gprc5d #iwgprc5d2025
Practical tips from @RahulBanerjeeMD #iwgprc5d2025 on managing skin and nail toxicities
Thank you for sharing and thanks to @TheLancetHaem for the opportunity to pen this commentary on an important update of a major practice informing - monumental study
Monumen-TAL progress in the treatment of relapsed multiple myeloma -
Ongoing drug development of novel agents and deployment of innovative combinations remains paramount in chasing the elusive cure
The Lancet Haematology thelancet.com/journals/lanha… #mmsm
At #IMS2024 we shared the first results from a pilot study of real time MRD-adapted deferral of ASCT in #mmsm absolutely could not have done this without the support of @End_myeloma and our fantastic MM team @uabmedicine
No pressure right! Debating @Myeloma_Doc
Amazing debate by @Myeloma_Doc and @SusanBal9 about which antigen to use post BCMA Rx: BCMA versus other?
#GDUHem
Imp manuscript from the Mayo group @ZanwarSaurabh showing the outcomes of pts w/ suboptimal response to DaraVCd in NDAL. I have traditionally switched to BCL2 inhibition ASAP if t(11;14) but for the rest such a tricky spot! Hopeful for TCE in this popn
nature.com/articles/s41375-0… – at Birmingham, AL
Wonderful morning discussing the importance of MRD in high risk MM especially on the heels of the ODAC – at South Carolina, USA
#DukeDebates in #mmsm
@SusanBal9 vs Dr Raymond Thertulien on induction and MRD for high risk
Dr Cristiana Chase vs Dr Taewoong Choi on CAR T vs transplant in relapsed MM
Always great to listen to my previous co-fellow @UrviShahMD talk passionately about nutrition and myeloma – at South Carolina, USA
Excellent thread on cilta-cel, only point I would highlight is if you progress on bridging therapy, your risk of fatal outcome 🔝 and in that situation I would not proceed directly with cilta cel but consider other options to lower disease burden! – at Birmingham, AL
#mmsm
How to counsel patients about Cilta Cel using the data from
CARTITUDE-4 and FDA ODAC meeting for earlier use
With data of Cilta cel and Ide cel, assuming having access to both for a given patient, I will personally chose Cilta cel (I explained this before)
🧵
When we presented this at EHA, less apparent but important to await data from additional patients and f/u at RP2D
Interesting kinetic profile of GPRC5D CART cells- (n=26) hence preliminary
- biphasic ?
- higher median at 6 months than ide-cel ( will this persistence translate to longer PFS )
(Sadly all cilta-cel articles are behind a paywall @JanssenUS )
#ASH23
Fantastic time as always connecting with friends, mentors sharing and learning amazing science @ASH_hematology @NBahlis @kordeneha1 @OmarNadeemMD Dr. Zelenetz – at San Diego, CA
Encouraging early data showing IMiDs and possibly CelMODs can improve on the response to immunotherapy @MileHighMyeloma @End_myeloma
Applaud the massive effort @mtmdphd undertakes every year to give us a glimpse of the best of #mmsm at @ASH_hematology and grateful to be included on this list!
Myeloma / Plasma Cell Dyscrasia ~ #ASH23Top10 (or so) #mmsm #mmMRD #ASH23 - @mtmdphd *DRAFT* Table Update: Nov 28, 2023 cc @grpetersen1 & @MyelomaTeacher @szusmani
