Resident at @UofTUrology, HRM PhD @HEI_mcmaster, MD, MPH at TUMS
Toronto, Ontario
Joined March 2016
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For the first time, our evidence synthesis published in @EUplatinum suggests HIGH certainty in prostate cancer mortality benefit with PSA screening by using #GRADE methodology.
Thanks to @DavidDan_Ngn for co-leading this #SRMA and all the collaborators.
🚨 In our meta-analysis in @EUplatinum, longer RCT follow-up now provides HIGH certainty in a prostate cancer mortality benefit from screening
authors.elsevier.com/a/1n2mP…
Earlier syntheses found uncertain evidence of little or no PCSM benefit
Some thoughts/highlights below 👇
Very few stories coming out of Iran (due to #DigitalBlackoutlran) are horrifying!
The unverified number of people killed (2-12K, might never be verifiable) and the barbaric brutality (machine guns, shoot to kill order, executing woundeds in hospitals, etc.) is beyond imaginable!
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Excited to share that #AppealTrial Update is published!
This RCT looks at antimicrobial prophylaxis before SWL. The final paper to come out soon. Our aim improve the previous low-quality evidence.
Thanks to the amazing leadership by @Phil_Violette @KariTikkinen and @GuyattGH
🔥 HOT OFF THE PRESS 📷
@EurUrolFocus published the Clinical Trial Update of the #AppealTrial
>1,700 participants completed the trial; the analysis is ongoing
APPEAL will establish the efficacy of antimicrobial prophylaxis for SWL procedures #EBM
More: authors.elsevier.com/a/1jYo%…
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Amazing work by #CLUEWorkinggroup.
Stay tuned!
Would you find online tool helpful for #thromboprophylaxis decisions in urologic, general abdominal and gynaecologic surgeries?
We thought so with @will_s_t & @LauriLavikainen
Tool helps also the upcoming #ARTStrial
Not yet publicly released, so, feedback very welcome! #EBM
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Very excited to announce that our #APPEALtrial has completed patient recruitment! Thanks to the great team who made this possible.
Great news! We have today completed recruitment at >1,700 patients to #APPEALtrial examining antibiotic prophylaxis pre shock wave lithotripsy #SWL
Thx to patients, funders & our global team 🇫🇮 🇨🇦 🇮🇷 🇶🇦 🇨🇭 🇷🇺 🇧🇷 🇸🇦 🇮🇩
We’ll do our best to publish the results soon #EBM #eau22
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I am hugely grateful to have the best mentor anyone can even imagine!@GuyattGH
Honorary doctorates of the University of Helsinki, Faculty of Medicine 🇫🇮
Congrats and thanks to your immense contributions to medical science 🤗
#honorarydoctorate #kunniatohtori #promootio
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This is a dream come true! I am going to become a urologist! Cannot wait to start this amazing next chapter with my new family at @UofTUrology and @CanUrolAssoc !
#CARMS2022
Happy new Persian year (Nowrouz) to all! May this be a year of peace, health, and prosperity for all.
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A great read!
Evidence-based Urology: Subgroup Analysis in Randomized Controlled Trials
buff.ly/3Acjube
@TPKilpelainen @KariTikkinen @robinvernooij
Congrats to all the future urologists who matched today!
You are all inspirational, especially @Sahareftekharz!
Looking forward to #CaRMS match.
#UroMatch2022 #AUAMatch @AmerUrological
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Unpopular opinion, but so true!!
Journals’ foolish focus on primary outcomes is driven by a misguided fixation on hypothesis testing. Patients are interested in relevant outcomes, and estimated magnitudes of effect. #Clinicians, #systematic reviews and #guidelines should ignore specification of primary outcome
This is a very interesting study suggesting polycythemia is potentially the mediator in the causal relationship between #testosterone therapy and cardiovascular events.
I am interested to know if the HCt value and cardiovascular risk are linearly associated in future studies!
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This is an amazing read to help you better understand how inconsistent the concepts of missing data management and ITT are used. A better understanding of how these two are relevant in each study is very helpful for medical literature users.
Confused about how intention to treat fits in with missing data (lost to #follow-up). This decade old paper remains the best to tell you why you are confused (guidance differs in confusing ways) and to clear up the confusion.
/bit.ly/3nsBQ2V
An amazing issue with great practical epidemiology issues explained for urologists (though relevant for every clinician).
Thanks to @KariTikkinen @GuyattGH for this.
Issue 7.6 - Clinical Epidemiology in Urology is available online!
Thank you to our Guest Editors Kari Tikkinen and Gordon H. Guyatt and to all that contributed to this fantastic issue!
buff.ly/3FG7xvA
@KariTikkinen @GuyattGH
I absolutely find this crucial for the authors and often overlooked!
As #scientists we should decide on most plausible truth and present that. Particularly if writing for #clinicians, pick the one best analysis and focus on that. No #fixed and #random, or #frequentist and #Bayesian, and leave the poor clinician to choose!
@PabloACoello
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Urology is an amazing medical field with both clinical and research potentials! Suggest watching this video to all med students!😍😍
Check out the CUA's fantastic video series on why YOU should be a UROLOGIST cua.org/what-is-urology @CanUrolAssoc
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A crucial concept for all researchers and clinicians!
When a study does not find an association, it does NOT mean there necessarily is no association.
Interpreting negative results 1
I am involved in a #systematic #review looking at whether a particular therapy is associated with a harmful effect. The summary from the student leading the project was “therapy x is not associated with outcome y”. Wrong!
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Very proud to be on the amazing @CanUrolAssoc #ED_guideline panel. We decided to use GRADE methodology to reach evidence-based and transparent recommendations. A great win for the Canadian urology community toward practicing evidence-based urology.
Check out the new @CanUrolAssoc ED guideline using GRADE ✅ published in CUAJ today! cuaj.ca/index.php/journal/ar…
Proud of our team and guideline...Borna Tadayon, Matt Roberts, @JDCampbell_MD, @RyanFlannigan00, Phil Bach, @PremalPatelMD, @GLangille, @yonah_krakowsky, @Phil_Violette
@TrustinDomes @Phil_Violette @yonah_krakowsky @JDCampbell_MD @PremalPatelMD @GLangille @RyanFlannigan00 Matt Roberts @GRADE_WG @GRADE_WG @MacUrology @HEI_mcmaster
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It’s going to be a great discussion!
Uncertain if good idea to use #desmopressin for #nocturia (in elderly)?
Check our #AUA21 plenary crossfire debate with Profs. Alan Wein, Roger Dmochowski & Jeff Weiss, chaired by @GeroUroTLG on Sun afternoon/eve in 🇺🇸 and after midnight in Europe.
aua2021.app.swapcard.com/eve…
#EBM
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