
A preclinical to clinical research team at the @ottawahospital, working to accelerate #bench2bedside translation.
Ottawa, Ontario
Joined May 2018
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New @BioCanRx funded work in Transfusion Medicine Reviews!
Our IPD meta-analysis (89 trials, 2,331 pts) reveals key modifiers of CAR T-cell efficacy & safety:
✅ Allogeneic > Autologous
🎯 CD19 combos > CD19 alone
⚠️ Bridging therapy ↓ response
🔗 Read: dx.doi.org/10.1016/j.tmrv.20…
The Blueprint Translational Research Team retweeted
The importance of including patient voices when appraising new drug treatments for strokes is backed by meta-analyses of several studies.
elifesciences.org/digests/10…
New in @eLife 🧠
CCR5 antagonists show promise for stroke treatment in preclinical studies — but the evidence has gaps.
Our patient-led systematic review reveals opportunities & limitations for clinical translation.
🧪➡️👥
Read more: doi.org/10.7554/eLife.103245
#StrokeRecovery #CCR5
We're excited to be sharing another edition of our LabPartners newsletter, highlighting our work to champion patient engagement in preclinical laboratory-based research! Read the full newsletter here: shorturl.at/3CPCe
You can also hear our PhD candidate, Matthew Jeffers, speak about this work at Plenary 3 of the @StemCellNetwork #TMM2024 meeting on November 5 in Montreal. Hope to see you there!
Interested in what #preclinical 🐭 evidence is needed to advance your new #celltherapy 🔬 into #clinicaltrials 👩🔬? We synthesized key guidance from over 60 regulatory agencies worldwide to help accelerate your research. doi.org/10.1186/s12916-024-0…
Interested in what #preclinical 🐭 evidence is needed to advance your new #celltherapy 🔬 into #clinicaltrials 👩🔬? We synthesized key guidance from over 60 regulatory agencies worldwide to help accelerate your research. doi.org/10.1186/s12916-024-0…
We're excited to be sharing the second edition of our LabPartners newsletter, highlighting our work to champion patient engagement in preclinical laboratory-based research! Read the full newsletter here: canva.com/design/DAGJzfQz5hA…
The Blueprint Translational Research Team at the Ottawa Hospital Research Institute has created a policy brief outlining how patient engagement can be promoted in preclinical laboratory-based research! Read the full policy brief HERE: t.ly/4Re6d
The Blueprint Team is excited to be launching a newsletter focused on our program to facilitate patient engagement in preclinical laboratory research! Available here: shorturl.at/cfDIR
The Blueprint Team is excited to be launching a newsletter focused on our program to facilitate patient engagement in preclinical laboratory research! Available here: shorturl.at/cfDIR
Great presentations from PhD candidates Matthew Jeffers and Dr. Michael Verret at SEPH Research Day! 🤩
Dr. Michael Verret's work was highlighted in the SPOR December newsletter. What an excellent example of patient engagement in opioid minimization research! 🎉 suivi.lnk01.com/v/443/a0f77b…
Congrats 🎉 to Blueprint #VanierCanada scholar Matthew Jeffers and @CCAC_CCPA post-doc @AileenMacLellan in this new #PLOSBiology perspective on how we can improve prospective registration of animal studies!
Thanks to @IanDGraham1 for his mentorship in #knowledgetranslation!
Prospective #registration of animal studies could improve research transparency and reduce redundancy.
@ManojLalu @AileenMacLellan @Marc_T_Avey @JuliaMenon18 &co argue that registration should be integrated as part of animal #ethics review.
#PLOSBiology
plos.io/3turO6U

ALT Preclinical and clinical researchers work together to build a helical staircase that ascends to medical innovation. Image generated by the authors using Stable Diffusion by Stability.ai. The authors supplied text inputs into the model based on the article themes that resulted in the image output shown.
The Blueprint Translational Research Team retweeted
Un grand bravo aux boursiers #VanierCanada 2023 de l’@uOttawa qui cherchent à développer des solutions proactives en santé et à améliorer notre qualité de vie grâce à leurs projets de recherche novateurs. Félicitations!
Blueprint's very own, Matthew Jeffers, highlighted here! Outstanding work and congratulations to all #VanierCanada Scholars!👏👏👏👏
A round of applause for @uOttawa’s 2023 #VanierCanada Scholars who are striving to develop proactive health solutions and improve our quality of life through their innovative research projects. Congratulations to all!
The Blueprint Translational Research Team retweeted
A round of applause for @uOttawa’s 2023 #VanierCanada Scholars who are striving to develop proactive health solutions and improve our quality of life through their innovative research projects. Congratulations to all!


















