Physician, Scientist, IT developer & Filmmaker

Joined February 2014
Teus Kappen retweeted
A CERN breakthrough may reveal why anything exists. In a landmark discovery at CERN’s Large Hadron Collider, physicists have detected subtle asymmetries in the decay of matter and antimatter. For the first time, CP violation—an imbalance in the behavior of particles and antiparticles—has been observed in baryons, the building blocks of protons, neutrons, and essentially all visible matter in the universe. This finding addresses a profound cosmic mystery: the Big Bang should have produced equal amounts of matter and antimatter, which annihilate upon contact. In theory, they should have obliterated each other, leaving only energy behind. Yet the universe exists, filled with stars, planets, and life—evidence that a minute surplus of matter escaped annihilation. Scientists have hunted for the mechanism behind this asymmetry for decades. CP violation was previously observed in mesons, but baryons dominate the material world, making this new result far more significant. By analyzing 80,000 decays of the lambda-beauty baryon (Λ_b), researchers found that its antimatter counterpart decays at a slightly different rate—by roughly 2.5%. The result is robust, with a statistical significance of 5.2 sigma, meaning a less than 1-in-10-million chance of being a fluke. The Standard Model predicts some CP violation, but far too little to account for the matter-dominated universe we observe. While this breakthrough doesn’t resolve the puzzle, it strongly suggests physics beyond the Standard Model—potentially pointing the way to the forces that allowed matter to prevail. ["Observation of charge–parity symmetry breaking in baryon decays." Nature, 2025]
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Ik heb geen lichten aan laten staan en net nog met de auto gereden. En nu maakt u van uw probleem, mijn probleem. Wat een service zeg.
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Teus Kappen retweeted
I hope that @annloh @ProfGroenwold @MaartenvSmeden who authored a wonderful new paper on penaliziation vs. data reduction will answer some questions posted on datamethods. #Statistics
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New in JMIR Cardio: Continuous Data-Driven Monitoring in Critical Congenital #heart Disease: Clinical Deterioration Model Development dlvr.it/Sp6kzf
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Terms explained: Statistics -> data analysis Machine learning -> data analysis Artificial intelligence -> data analysis Data analytics -> data analysis Data science -> data analysis Statistical learning -> data analysis
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Implementing a prediction model is an intervention. We need more of these kind of studies 👇
Randomized clinical trial shows machine learning mortality predictions & behavioral nudges to cancer clinicians led to significant increase in rate of serious illness conversations & altered outcomes of end-of-life care for pts w/cancer. ja.ma/3iBxXJF #HPM #EOL
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We are all being rightly encouraged to be #efficient in our trial design & conduct. Efficiency comes primarily through design choices … whether classic or more modern efficient designs … a few reflections below 1/7 #MethodologyMonday
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I am having a blast at our cozy Learning Health Data Platform at #healthri2022
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Patients consider a specific consent for anesthesia to be superfluous... Makes one wonder #qualitative #DigitalTransformation #PatientExperience authors.elsevier.com/sd/arti…
I used OpenAI’s newest code model to make simple versions of games like Wordle, VR mazes and Zelda ENTIRELY through natural language. I told it what I wanted and did ZERO editing/coding. Post with demos: andrewmayneblog.wordpress.co…
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Wondering what all that talk about calibration of prediction models is about? Then this paper led by @BenVanCalster might be a good starting point link.springer.com/article/10…
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Zou onze overheid dan toch gelijk gaan krijgen met de huidige lockdown? Belangrijke informatie uit het Verenigd Koninkrijk
THREAD on England & Omicron and what is going on. My take on it. TLDR: things are pretty bad and I'm sad & bewildered at lack of govt action and general levels of hopium. 1/18
Teus Kappen retweeted
Nice (reminder) slide by @kdpsinghlab at @SymposiumML4H - just because you can build a 'good' model doesn't mean using it will be effective - highlighting the importance of (RCT) evaluation. -> tinyurl.com/j2r4sbn3 (development) -> tinyurl.com/2p8fhk6m (RCT evaluation)
No caption needed. Just beauty over here.
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Teus Kappen retweeted
Humans still seem to be better than technology when it comes to the accuracy of spotting possible cases of breast cancer during screening, suggests a new review published @bmj_latest ow.ly/qc2G50G1vGd
Can we finally get rid of this very restrictive rule?
The majority of adults have a gastric volume < 1.5 ml/kg after implementing a liberal fluid policy @BJAJournals @TeusKappen bit.ly/3wkXTKf
Shame on you @AnnalsofSurgery
👇How to stifle debate and raise concerns on published articles in @AnnalsofSurgery.
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Perioperative hypotension 2021: a contrarian view @BJAJournals @TeusKappen bit.ly/3aF3rY6
Artificial Intelligence is a tool that should have a practical goal, and not be a goal in itself. In our view, this is what happened with an A.I. application for low blood pressure during surgery. sciencedirect.com/science/ar…
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