Structural biologist @GlycoGriffith | Infection and Immunity | NAD+ | Protein Crystallography | cryoEM | 🇳🇴

Gold Coast, Queensland
Joined June 2019
ECPM2024 registration is now open eventbrite.co.uk/e/east-coas… Award opportunities for student and postdocs: Best talk and poster presentations awards Student travel awards Early career researcher (<5 years post PhD) can be considered for the BioMolecular Horizons (BMH)2024 award.
4
6
402
Congrats @brongriff & Dr Yun Shi on your @nhmrc grants! A/Prof Griffin's work on early intervention strategy for kids with burns & Dr Shi will study brain biomolecule that protects nerve cells in neurodegenerative disorders @GlycoGriffith @Griffith_Health news.griffith.edu.au/2024/05… – at Brisbane, Queensland
5
6
924
QPG would like to announce the 2023 Queensland Protein Group and Ross Smith ECR Award Symposium will be held on Tuesday 17th October at the Queensland Brain Institute from 1 – 5pm followed by a mixer and presentation of the awards (see attached flyer for more information).
3
4
549
Dear QPG member, the deadline is coming up soon, get your abstract and CV ready for an exciting opportunity to speak at ASBMB 2023 and get your registration costs covered by QPG.
4
4
833
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
26
140
31
449
85,526
Excited to share our preprint on using unsupervised learning to find inhibitors from fragments hits. The idea is learning a distance distribution of pharmacophores from fragment hits, and then scoring a large purchasable library using that. (1/3) biorxiv.org/content/10.1101/…
14
29
1
166
So excited that we finally have the ACTIVE NLRP3 inflammasome structure, thanks to super talented Le Xiao @LeXiao17, and Venkat Magupalli @MagupalliVenny! nature.com/articles/s41586-0… – at Boston, MA
44
252
37
1,122
Dear QPG members. Please vote for your new QPG executive, Treasurer, Secretary and Website coordinator! surveymonkey.com/r/RV276PP
4
5
Thomas Ve retweeted
2 new papers in JCI from the DiAntonio/Milbrandt labs shed new light on Sarm1’s role in neurodegeneration. 1)Chronic Sarm1 activation leads to macrophage recruitment that plays a role in axon degeneration. 2)Eliminating Sarm1 slowed AXD in a model of CMT. tinyurl.com/27f5udjm
1
4
Thomas Ve retweeted
Out today @cellhostmicrobe: An expanded arsenal of bacterial immune systems Even if you previously read the preprint, don’t miss a major new result on the bacterial SEFIR domain, a homolog of human immune domains A thread 🧵 1/9 sciencedirect.com/science/ar…
4
107
10
304
It's on again in 2022! The Ross Smith ECR Medal Symposium this year will be held on 15th November at the Glycomics Institute, Griffith University. Please apply for either ECR or student prizes and look forward to seeing you there! eventbrite.com.au/e/2022-ros…
The Kranzusch lab (kranzuschlab.med.harvard.edu) and Sorek lab @SorekLab report discovery of gcADPRs as a new class of antiviral signals. @nature nature.com/articles/s41586-0…
40
4
125
Released today @EMDB_EMPIAR & @PDBeurope, & published @ScienceMagazine, #CryoEM structure of the Toll/interleukin-1 receptor domain from #AbTir in complex with 3AD. Study by Mohammad K. Manik et al., @ 2.74 Ă… resolution.
1
10
29
Happy to share our cADPR paper out today @Science: science.org/doi/10.1126/scie… A wonderful collaboration between @Kobe_Lab_, Milbrandt & DiAntonio @WUSTL, @MingGuoChu, @Muzzapythopath and us @GlycoGriffith Congratulations @manikrpc, Yun Shi, @insulin_SulinLi and all co-authors!
We are happy to announce that our paper about signaling molecules produced by bacterial TIRs is published in Science today science.org/doi/epdf/10.1126…. It was a concerted effort from many groups around the world. Thanks @Piperproduction for rendering for our EM structure of AbTir.
2
8
1
36
🚨New chemical tools for SARM1!🚨 Very excited to see our work published today in @PNASNews detailing the chemoproteomic discovery of stereoselective/site-specific allosteric #SARM1 inhibitors. Huge thanks to #LLJRC, @Andrea_Loreto1, and all co-authors! pnas.org/doi/epdf/10.1073/pn…
2
14
3
50
Thomas Ve retweeted
Did you know there are lots of similarities between the innate immune systems of animals/plants and the phage defense systems in bacteria? Check out our new study by the amazing trio Alex (Linyi) Gao, @maxewilkinson, and @thestrecker. Congratulations! science.org/doi/abs/10.1126/….
4
160
13
692