Talmbout 💹🧲 retweeted
It’s almost incomprehensible how wide the distance is between someone who’s working at the frontier with AI and basically everyone else right now.
The crazy thing is these lines are not converging, but only growing farther apart. If the curve of AI progress had leveled off, it would certainly have given most people and companies time to catch up or implement their workflows in a standardized way. The technology would have neutralized competitive advantage because everyone would be using it the same way.
But what’s happened is the opposite. The curve of AI progress is basically going vertical right now, which means if you had codified your processes 3-6 months ago you’re likely already behind again. Now imagine most companies that kicked into gear a year ago and thought that they were done. Even further behind now.
I’ve never seen a technology in my life and career that improves at this rate, which consequently means you need to upgrade your expectations at a similar rate. Our brains weren’t wired for this, and our organizational change management processes certainly weren’t either.
With any form of recursive self improvement, things just get wilder. It’s a time when you will need to be constantly reevaluating the things that didn’t work just a couple months ago to see if they now can be solved. AI native companies certainly have a strong advantage due to this right now, so now it comes down to can the bigger companies keep up. Wild times.
Talmbout 💹🧲 retweeted
i think people underrate the degree to which crypto and ais fates are intertwined. we have even not seen the half of it yet
radical decentralized capital technology with massive incentive to keep online + uncontrollable agentic forces which directly converts capital to labor
If you look closely enough, breakthroughs in everything are accelerating exponentially.
An exponential always starts off looking small.
this might be my last normal tweet before biotech goes vertical
i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs
but there is a massive shift happening in human biology right now.
it's sitting in press releases and almost nobody reads them
the last 6 months alone:
- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave
we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday
stick around, it's going to get weird
bio/acc
Talmbout 💹🧲 retweeted
Surfers spend hours paddling through waves, and this guy thinks their secret to staying fit is accidentally drinking the ocean.
Then he gets asked how confident he is in recommending it. That answer deserves a replay.
Wellness has gotten so weird that “exercise is good for you” apparently needs a competing theory involving imported French seawater.
Talmbout 💹🧲 retweeted
Announcing three major scientific discoveries, one each in mathematics (harmonic analysis), computer science (complexity theory), and physics (quantum field theory).
AI starting to help us improve our understanding of the universe! openai.com/index/building-sc…
Talmbout 💹🧲 retweeted
This is what happened today ❤️❤️😁💹 🧲 for life!! @swaggytheaeon
Agentic AI is for the delusional, the retardmaxxxers, the dreamers, the ADHD builders, the wanderers, the optimists, the AEONS, the neurodivergents.
We're in a ruly special time. Biggest opportunity since the dotcom boom. Seize this moment...
Talmbout 💹🧲 retweeted
BREAKING: Indonesia seizes over 1 tonne of ketamine worth $192 million from a tanker arriving from Malaysia.
















