Professor @UChicago. Network Director @UChicagoMed. Clinical Innovation; VT/VF Ablation; Bioengineering. Penn Alum. Dedicated to the Academic Mission.

University of Chicago
Joined December 2009
Adjunctive targeted disruption of the Purkinje network improved outcomes after VT ablation in patients who also had evidence of VF. It is critical to review every episode of ICD therapy and plan accordingly.
A #JACCCEP study showed that in pts. w/ prior spontaneous polymorphic VT/VF, adjunctive Purkinje de-networking during VT #epAblation was associated with a substantial reduction in recurrent ventricular arrhythmias, w/ a modest increase in risk of LBBB. bit.ly/4hVN5xl
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William H. Sauer, MD retweeted
Excellence Across Cardiology: Congratulations to Our 2026 Castle Connolly Top Doctors The @UChicagoMed Section of Cardiology congratulates 10 faculty physicians named to Castle Connolly's 2026 Top Doctors list, honoring excellence in clinical expertise and patient care. Our distinguished faculty: • Rishi K. Arora, MD • Michael H. Davidson, MD (@mdavidsonmd) • Jeanne DeCara, MD • Sara Kalantari, MD (@SaraKalantariMD) • Sandeep Nathan, MD (@SandeepNathanMD) • Jonathan D. Paul, MD (@Jonathan_PaulMD) • William H. Sauer, MD • Atman P. Shah, MD • Matthew Sorrentino, MD • R. Parker Ward, MD Selected through peer nominations and rigorous research, Castle Connolly Top Doctors represent the top 7% of physicians nationwide. Spanning multiple specialties in cardiovascular medicine, this distinction reflects the expertise, leadership, and dedication to exceptional patient care across our Section. Please join us in congratulating all 10 physicians on this national honor.
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William H. Sauer, MD retweeted
Thank you to everyone who made @VTSymposium & the pre-con, PFA 101: From Bench to Bedside, a resounding success. @VTSymposium 2026 ON-DEMAND will be available soon to all conference attendees and later for general viewing. Keep an eye out for details on the 22nd Annual International VT Symposium 2027
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When we consider everything Michel Haissaguerre has already done for our field it is beyond inspirational to see how he continues to share his knowledge with us. The MEJ award is well deserved.
Live- 21st VT Symposium - Mark E. Josephson Memorial Lecture by Michel Haissaguerre- Structural basis of Ventricular Fibrillation- simultaneously published in JACC Clinical Electrophysiology- Congratulations to International team @VTSymposium @ACCinTouch
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William H. Sauer, MD retweeted
Live- 21st VT Symposium - Mark E. Josephson Memorial Lecture by Michel Haissaguerre- Structural basis of Ventricular Fibrillation- simultaneously published in JACC Clinical Electrophysiology- Congratulations to International team @VTSymposium @ACCinTouch
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Fascinating to consider the acute and longer term effects of PFA on fascicular tissue. I suspect that there will be a lack of durability for Purkinje tissue as it has a much lower metabolic demand compared to myocytes. Might need to be prepared for temporary pacing overnight.
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William H. Sauer, MD retweeted
Please join me and my international colleagues to celebrate the success and interest in the Physiology of Pacing Symposium. It is our 10th Anniversary. This will be a special and tremendous session and opportunity for anyone interested in pacing to learn more. Please join us.
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William H. Sauer, MD retweeted
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William H. Sauer, MD retweeted
Congratulations to @DrSouvikKDas on winning the Mark E. Josephson abstract competition @VT_Symposium #Epeeps #cardiotwitter #cardiology
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With VT Ablation Giants in NYC. The best part of the meeting is reconnecting with old friends. @Ed_Gerst @utedrow @JRWinterfield #AblateVT #VTS2026
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William H. Sauer, MD retweeted
Shaping the Future of Heart Failure Care at #HFSA2026 The @UChicagoMed Section of Cardiology is headed to Phoenix for the @HFSA Annual Scientific Meeting! Our faculty will present research and share clinical expertise across advanced heart failure, hemodynamics, mechanical circulatory support, and cardiac amyloidosis. Phoenix Convention Center | Phoenix, AZ October 9–12, 2026 Featured Faculty: Manreet Kanwar, MD Jonathan Grinstein, MD (@JonGrinsteinMD) Mark Belkin, MD (@MarkBelkinMD) Nitasha Sarswat, MD (@SarswatNitasha) Ben Chung, MD (@benchungmd) Nikhil Narang, MD (@Nikhil15) Together, their participation reflects the depth of clinical expertise, research, and leadership within our Section of Cardiology. Stay tuned for faculty presentations and session highlights throughout #HFSA2026.
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William H. Sauer, MD retweeted
Congratulations to Dr. Hena Patel, Director of the Women’s Heart Center (@hpatel824), on receiving the 2027 Preeclampsia Foundation Vision Grant Award! A member of the @UChicagoMed Section of Cardiology and founder of our Women in Cardiology (WIC) Program, Dr. Patel is dedicated to advancing cardiovascular research and improving care for women throughout their lives. Her research proposal, “Coronary Microvascular Dysfunction and Subclinical Myocardial Remodeling After Preeclampsia,” will investigate the potential long-term cardiovascular effects of preeclampsia in diverse populations. This highly competitive award supports research addressing health inequities in the United States. Please join us in celebrating Dr. Patel’s achievement and her commitment to advancing women’s heart health!
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This was a challenging case that we saw as a consult and managed effectively with coordination of subspecialty services. @BrighamWomens @utedrow @RobNKerley @KazziBrigitte
A Shark Fin Heart - A Case of Fulminant Myocarditis heartrhythmcasereports.com/a…
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We found abnormal Purkinje electrograms (prolonged and multiphasic) at sites where VF triggers were identified at the time of ablation. An important feature for understanding VF mechanisms.
Distinct Purkinje electrogram phenotypes at ventricular fibrillation trigger sites in idiopathic and structural heart disease @RobNKerley heartrhythmjournal.com/artic…
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William H. Sauer, MD retweeted
Substrate de-networking linked to greater freedom from VT/VF but more conduction system injury. Trigger-focused ablation may be considered first when PVC triggers are identifiable, reserving substrate modification for refractory/nontriggered VF jacc.org/doi/10.1016/j.jacep… #JACCCEP
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The best approach appears to be regionalized Purkinje network disruption. One thing I have learned is that the fascicular anatomy (discrete pathways) we were taught in medical school is wrong. It’s more like a web of intersecting fibers facilitating reentry.
Substrate de-networking linked to greater freedom from VT/VF but more conduction system injury. Trigger-focused ablation may be considered first when PVC triggers are identifiable, reserving substrate modification for refractory/nontriggered VF jacc.org/doi/10.1016/j.jacep… #JACCCEP
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William H. Sauer, MD retweeted
Ablation in Patients With LAAO Devices - William Sauer (@True_EP ) @rachelkaplanmd | @hhuang123 | @JDFDLz hemostasistoday.com/science/… #HemostasisToday
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Please take this poll.
Dear Friends: I would appreciate your response to this brief, anonymous poll of VT ablation after a first appropriate ICD shock. I will present the aggregate results at the VT symposium in NYC. Thank you for collaborating! forms.gle/FVAtvzMfzCBkkbZj6
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William H. Sauer, MD retweeted
Dear Friends: I would appreciate your response to this brief, anonymous poll of VT ablation after a first appropriate ICD shock. I will present the aggregate results at the VT symposium in NYC. Thank you for collaborating! forms.gle/FVAtvzMfzCBkkbZj6
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