Prostate Cancer Aficionado. Research @KU_Leuven @DanaFarber and @UCLcancer, EAU guideline associate @uroweb, Urology Resident @UZLeuven
België
Joined August 2015
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Out now: joint analysis of single cell and spatial transcriptomic data from 120 patients. Proud of this team effort!
Our investigation into the prostate tumor microenvironment is now out in Nature Comms: nature.com/articles/s41467-0…
We combined publicly available scRNA-seq data with in-house spatial transcriptomics samples to jointly anayze data from 120 patients. Here’s what we found 🧵 1/6
Wout Devlies retweeted
Privileged seeing the @ProBioTrial published in @NatureMedicine
My sincerest gratitude for all the dedicated doctors, nurses, lab personnel, trial managers, and most importantly, the patients who made this possible🙏
Thank you @komop_tgkanker for making ProBio possible in🇧🇪
🔥📢 The first results from the @ProBioTrial have been published in @NatureMedicine 🚀🌟
ARPIs outperform taxanes in metastatic #ProstateCancer: an outcome-adaptive randomized platform trial 🌟 nature.com/articles/s41591-0…
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Wout Devlies retweeted
European Association of Urology Guidelines on Urological Infections: Summary of the 2024 Guidelines by Jennifer Kranz et al.
Full article: buff.ly/3XRiw2b
@riccabar1 @rajan_vpillay @BauschKathrin @WoutDevlies @LeitnerLorenz @ManticaGu @GBonkat
#Medtwitter #UroSoMe
Wout Devlies retweeted
Amazing experience STEPS program! Nice Uroonco24. Thanks to the experts and colleagues!
Proud of our work from the Boston Lab on RT after neoadjuvant treatments in high-risk localized PCa: adjuvant RT rarely used and outcomes of both adjuvant and salvage poor. Patient selection will be key!
Outcomes of adjuvant and salvage RT in patients who have received neoadjuvant ARPI prior to RT for high-risk prostate cancer: our pooled analysis of trial patients published in #Prostatejournal - onlinelibrary.wiley.com/doi/…
Wout Devlies retweeted
"Double trouble for prostate cancer: synergistic action of AR blockade and PARPi in non-HRR mutated patients"
@joniau @LoicBaekelandt @WoutDevlies @devos_gaetan @EveraertsW
frontiersin.org/journals/onc…
Wout Devlies retweeted
Happy to see our work highlighted during this #Movember month! Don't forget the impact of #androgendeprivation on #bone in #prostatecancer patients! bit.ly/3G3LKkd
Great collaboration with our urology department @devos_gaetan @WoutDevlies @joniau
👇👇👇
2nd highlight from November issue
@KarelDavid_ & coll
Report that androgen deprivation therapy results in bone loss as early as after 12 weeks in patients with non-metastasised prostate cancer
Read bit.ly/3G3LKkd
Wout Devlies retweeted
🔬 #PROpel unveiled PARP-inhibitors potential in #PCa, unveiling new potential synergies beyond HRRm!
🎯 More trials are needed for validation beyond pre-clinical data and pinpointing the ARSI + PARPi synergy in non-HRRm patients!
@joniau @WoutDevlies
authors.elsevier.com/a/1i9mm…
Discover our work on the value of cystoscopy in bladder cancer detection, laying the basis for European and Canadian guidelines. Big team effort!
Diagnostic Accuracy of Cystoscopy for Detecting Bladder Cancer in Adults Presenting with Haematuria .@Uroweb @MariaJRibal @ahmostafid @WoutDevlies @JoepJdeJong @maxbruins @EmmaJSmith9 @Cathyyuhongyuan @Phil_Violette @McMasterU Bas, Nancy, Tahilita, Fabian sciencedirect.com/science/ar…
Proud on new paper from the Attard lab! Different novel insights in the PCa progression pathway.
Find out @AttardLab’s latest publication (nature.com/articles/s41467-0…) showing that lethal prostate cancer progresses to lethal disease via a limited number (two or three) of dominant clones, each harbouring patient-specific androgen receptor gene architectures.
Wout Devlies retweeted
Very proud to present the ARNEO study published in @EUplatinum!!
In high-risk PCa patients, neoadjuvant degarelix plus apalutamide prior to RP results in significantly improved pathological response compared to degarelix alone!
@joniau
A thread🧵👇:
authors.elsevier.com/c/1fow7…
Wout Devlies retweeted
Great opportunity for a trainee oncologist to join our team and become an expert on prostate cancer: atsv7.wcn.co.uk/search_engin…
Wout Devlies retweeted
Excited to share our new work on clinical enzalutamide resistance and lineage plasticity (LP) in prostate cancer through the @SU2C_PCF_WCDT out now in @NatureComms!
nature.com/articles/s41467-0…
@UMRogelCancer, @UMichCancBio, @umichrna, @PCF_Science, @DRSNmoonshot
Wout Devlies retweeted
#ARNEO: a randomized phase II trial of neoadjuvant degarelix with or without apalutamide prior to radical prostatectomy for high-risk #ProstateCancer. Presentation by @joniau @UZLeuven. #EAU22 written coverage by @zklaassen_md @GACancerCenter > bit.ly/3RjQqHl @Uroweb
Excited for this intensive week designing a follow-up trial for the ARNEO study among many brilliant researchers! @joniau @EORTC
And so, after a 2 years delay, we’re getting ready for the next #mccrworkshop.
6 intensive days working on #clinicaltrial protocols.
Congrats Diogo to a very interesting set of neoadjuvant treated PCa, nicely complementary to our ARNEO study. Excited to see your future work. @MolendoKUL @joniau @devos_gaetan
Happy to share the results of our randomized phase II of intense ADT prior to prostatectomy for high-risk prostate cancer, including PSMA/PET correlation with path outcomes! @DrRanaMcKay @Silke_Gillessen @SoaresAndrey @RafaelFCoelho2 @montypal @g_develasco @DRathkopf
A very interesting read from our collaborators on liquid biopsy testing in prostate cancer: PCF select is a panel to watch! #prostatecancer @joniau @MolendoKUL
.@PCF_SELECT #cfDNA assay detects #allelicimbalance (e.g. BRCA2, ATM, PTEN) in #prostatecancer plasma with high sensitivity. Consortium of @FrancescaBZNY @AttardLab @mishabeltran @ResearchWyatt @MarkARubin1 labs and teams! @PCF_Science @AIRC_it @CR_UK academic.oup.com/narcancer/a…
Congrats to my colleague @DeBruynHelene for her passionate invited talk at @BIDMChealth @Harvard about developing murine models to truly investigate bladder function. Both invasive and non invasive models were welcomed with enthusiasm! @EveraertsW @licr_leuven
Wout Devlies retweeted
...first results of PEACE 1 finally published...
authors.elsevier.com/c/1etg2…