@YaleAge

A growing interdisciplinary research program at Yale School of Medicine in Geroscience and the Biology of Aging.

 Yale University, New Haven, CT
medicine.yale.edu/yage/
Joined February 2022
  • Tweets182
  • Following23
  • Followers668
81Media
YSM Yale Center for Research on Aging (Y-Age) retweeted
Heidi Zapata, MD PhD@HeidiZapata77Oct 16
Enjoying a stimulating day of talks at the Tenth annual Glenn Aging symposium !@Yale @YaleWestCampus @YaleAge
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YSM Yale Center for Research on Aging (Y-Age) retweeted
YSM Pathology
@yalepathologyJun 11
Scientists from @YaleMed & other institutions develop 1st comprehensive atlas of human cellular senescence in #aging. @RongFan8 @MinaXu7 @Halene_lab @VishwaDeepDixi1 @YaleAge @CellPressNews bit.ly/4v7x4sn
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Hattie Chung@hattacaJun 19
Paper: nature.com/articles/s43587-0… Work with the talented @Tammyinlab #AlisonKochersberger @sophiamszady @jenngarrison and many others (Cover Art: Alison Kochersberger) @YaleMed @YaleAge @MCDB_Yale @BuckInstitute @broadinstitute

Aging disrupts spatiotemporal coordination in the cycling murine ovary

Nature Aging - Ovarian cycles of follicle development, ovulation and tissue regeneration require cooperative functions of constituent cells. Here the authors provide a spatial atlas of the aging...

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Nature Aging@NatureAgingApr 13
Online now!✨Mining the longitudinal plasma proteome of CALERIE participants, @MishraManish29, @Hee_Hoon_Kim et al link C3a to inflammaging. In aged mice, visceral fat macrophages produce C3a and neutralizing it blocks inflammaging @VishwaDeepDixi1 nature.com/articles/s43587-0…

Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic...

Nature Aging - Applying proteomics to longitudinal plasma samples from calorically restricted participants of the CALERIE trial, Mishra, Kim and colleagues link complement protein C3a to...

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
P. Kent Langston@Langston_LabMar 3
New in @NatImmunol: we uncover mechanosensing by Piezo1 on mesenchymal stromal cells as a fundamental mechanism of stress-induced immunomodulation in skeletal muscle, particularly in contexts of acute exercise and injury. nature.com/articles/s41590-0…

Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and...

Nature Immunology - Mathis and colleagues describe how mesenchymal stromal cells in the muscle sense mechanical changes in their microenvironment induced by exercise or injury via Piezo1, which...

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Junyue
@junyue_caoFeb 26
New paper alert 🚀 Our organism-wide single-cell ATAC-seq atlas of mammalian aging is now out in @ScienceMagazine, led by our fantastic graduate student @ziyu__lu from @RockefellerUniv! science.org/doi/10.1126/scie…
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Nature Metabolism
@NatMetabolism15 Dec 2025
Top #Citations 2025: 5️⃣ @VishwaDeepDixi1et al (@YaleMed) show that cysteine depletion leads to adipose tissue browning and rapid weight loss in mice and humans. nature.com/articles/s42255-0…

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Nature Metabolism - The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Nature Aging@NatureAging15 Dec 2025
Online now!✨RESEARCH: @inhwajang_ et al show that GDF3 drives endotoxic inflammation and lethality in old mice by reshaping chromatin in inflammatory adipose tissue macrophages @CamellChristina nature.com/articles/s43587-0…

GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility...

Nature Aging - Jang and colleagues demonstrate that GDF3 reshapes the chromatin landscape of inflammatory adipose tissue macrophages and drives endotoxic inflammation with age. Pharmacological...

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Jonathan Kipnis 🟦
@jonykipnis16 Dec 2025
Very interesting paper on the history of Treg and the many contributions of those recognized but also, importantly, of those not recognized by the @NobelPrize || The history and promise of Treg cells sciencedirect.com/science/ar…
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Thomas Gill@MrDisability15 Dec 2025
Learn about the @YaleMed PEP Study, a wonderful resource for disability research in older persons pubmed.ncbi.nlm.nih.gov/3224…
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Yale School of Medicine
@YaleMed7 Nov 2025
How can older adults maintain their independence as they #age? Yale Department of Internal Medicine’s Thomas Gill, MD, joined the Health and Veritas #podcast to share what he’s learned over a career of #research: medicine.yale.edu/news-artic… @YaleIMed

Quick Question: Can I Prevent Physical Decline as I Age?

During an interview on the Health & Veritas podcast, Thomas Gill describes why physical activity remains important as we age.

medicine.yale.edu
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YSM Yale Center for Research on Aging (Y-Age) retweeted
YSM Pathology
@yalepathology8 Sep 2025
Meet our new Assistant Professor of Pathology, @Langston_Lab, and learn about his research into exercise and immunity. Dr. Langston is also a member of @YaleAge at @YaleMed. bit.ly/3V67Wli
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Eric Topol
@EricTopol14 Aug 2025
As I wrote in SUPER AGERS, the immune system is the key to modulating our aging process and the opportunity to extend healthspan. Today @NatureAging 7 new articles, summarized here, that reinforce its central role nature.com/articles/s43587-0…
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Nature Aging@NatureAging15 Aug 2025
🎉Immune aging focus 🎉@Hee_Hoon_Kim and @VishwaDeepDixi1 review how the coupling of the immune system to cellular and organismal metabolism affects aging nature.com/articles/s43587-0… rdcu.be/eARAG
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Rong Fan@RongFan825 Jun 2025
Highlight of a stunning work by my colleague @VishwaDeepDixi1 of @YaleAge on how removing a single amino acid induces adipose tissue thermogenesis and rapid weight loss. 👏👏👏
Nature Reviews Endocrinology@NatureRevEndo24 Jun 2025
New content online: Cysteine deficiency induces rapid weight loss via adipose tissue browning bit.ly/3HYRqjH
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Rong Fan@RongFan85 Jun 2025
Congratulations @VishwaDeepDixi1 and team!! How cool it is for a single amino acid cysteine to completely change organismal metabolism!!! 🤩🥳👏👏 @YaleAge @yalepathology @YaleMed “Cysteine depletion triggers adipose tissue thermogenesis and weight loss” nature.com/articles/s42255-0…

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Nature Metabolism - The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Bandy Chen@chen_bandy3 Jun 2025
nature.com/articles/s42255-0… Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Nature Metabolism - The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.

nature.com
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Thomas Gill@MrDisability8 May 2025
I was pleased to talk with @hmkyale & @thehowie on the podcast #HealthAndVeritas, produced w/ @YaleSOM & @YaleSPH. Listen as we discuss prehabilitation programs to prevent functional decline, the events that precipitate disability and shape recovery & current geriatric practice.
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Rong Fan@RongFan822 Jan 2025
Thrilled to have Dr. Peter Adams, @AdamsBioAging , San Diego SenNet TMC PI, visiting us and giving a seminar on epigenetics in senescence, aging, and disease. 🤩🤩😒 @YaleAge @sennetresearch @yalepathology
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YSM Yale Center for Research on Aging (Y-Age) retweeted
Yale Internal Medicine@YaleIMed17 Dec 2024
ATTN YALE: The Yale Pepper Center is soliciting letters of intent for new initiatives in translational geroscience. Learn more about the geroscience initiative, including scope, eligibility & deadlines. @Yale_OAIC @yalepathology medicine.yale.edu/internal-m…

Funding Opportunity for Translational Geroscience

The Yale Pepper Center is soliciting letters of intent from Yale faculty for new initiatives in translational geroscience. This pilot grant program, sponsored

medicine.yale.edu
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