@Yildiz_Lab

Our lab at UC Berkeley uses biophysics to understand the mechanisms that underlie the cellular organization and motility. Account managed by lab members.

Joined August 2020
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  • Followers457
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nature.com/articles/s41467-0… Our paper on cargo adaptor regulation of kinesin and dynein motor proteins is now out at Nature communications. Work done by @aslannmerveee , John Canty and Andrew Hensley. Congratulations to the authors!!

TRAK adaptors regulate the recruitment and activation of dynein and kinesin in mitochondrial...

Nature Communications - The mechanisms of microtubule-based mitochondrial transport remain poorly understood. Here, the authors show that the mitochondrial TRAK adaptors activate the...

nature.com
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Yildiz lab members are enjoying #BPS2023 ! Lots of great science and looking forward to the poster sessions on MT motors tomorrow!
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Yildiz lab is heading to #BPS2023. Check out Merve's talk on Sunday the 19th, describing our recent paper on cargo adaptor regulation of motor proteins!
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Visiting graduate student Eui-Jin also has a poster on Wednesday.
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The gangs(mostly) all here! Hope everyone is enjoying BPS 2022. Make sure you come check out Amanda’s poster at tomorrows session (1:45) on nucleocapsid condensates and her talk about telomere LLPS at 5:30!!!
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MORE NEW RESEARCH! Here's our latest report on the shelterin complex's compartmentalization of telomeres. sciencedirect.com/science/ar…
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New Year, New Paper! Check out our latest collaborative work on the interactions between Kinesin-1 and MAP7. Also stay tuned for new work on shelterin next week! science.org/doi/10.1126/scie… #kinesin #MAPs #molecularmotors #biophysics #microtubules

Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein...

MAP7 binds to microtubules and activates kinesin-1 motility despite the overlap between their tubulin-binding sites.

science.org
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Yildiz Lab holiday lunch. Wishing everyone a happy holidays!
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Ahmet Yildiz retweeted
Ruensern Tan@RuensernT11 Nov 2021
Preprint out of my final work at the McKenney lab. biorxiv.org/content/10.1101/…

Microtubule Lattice Spacing Governs Cohesive Envelope Formation of Tau Family Proteins

Tau is an intrinsically-disordered microtubule-associated protein (MAP) implicated in neurodegenerative disease. On microtubules, tau molecules segregate into two kinetically distinct phases,...

biorxiv.org
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A new paper from our lab. Covid-19 uses phase separation to package viral particles. Congratulations! @AmandaJack27 @ferro_luke journals.plos.org/plosbiolog…

SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

The packaging of the SARS-CoV-2 genome is mediated by the nucleocapsid (N) protein; this study shows that the N protein forms liquid condensates with viral genomic RNA and identifies small molecules...

journals.plos.org
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Belated graduation celebration for our newly minted Dr. @ferro_luke and Dr. Yasin Ezber. Farewell! Don't be strangers! 🎓🎓
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Lab bonding with axe throwing. Turns out the Yildiz lab would fair pretty well in the zombie apocalypse.
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Journal Club: The concept of a dynamic MT lattice is heating up. Severing enzymes and motors, Oh My! nature.com/articles/s41563-0…
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Thank you to lab member (past and present) for attending the first post-COVID Yildiz lab BBQ.
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Ahmet Yildiz retweeted
Carter Lab@Carter_Lab10 May 2021
Dynein 2021 - Round Table Discussions. @ErikaHolzbaur @alanbrownhms @RuiZhangWUSTL @SamReckPeterson @jbwallingford @surrey_lab @GaiaPigino @morgan_desantis @DutcherLab @VaishAnanth and more For full details dynein2021.org/ Registration Open!
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Great work further dissecting the domains of kinesin in human disease. Work started when the first author was "just" an undergrad! advances.sciencemag.org/cont…
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Meet our newly minted PhD candidate Jon Fernandes. Celebrations with bubbly and burritos.
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Mega journal club! Two great TRF2 papers showing its power in stem cell pluripotency and the tubulin code showing unique regulation of dynein in flagella. nature.com/articles/s41586-0… nature.com/articles/s41586-0… science.sciencemag.org/conte…
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