structural biology, computational biophysics, genomics, ML/AI |🏳️‍🌈 (my own posts and opinions)

San Francisco, CA
Joined April 2015
Also noting that the person biking fell into the travel lane where, if there was a car/truck driving there, they would have been run over and potentially killed. Sandwiching people between two lanes of driving cars/trucks is a dangerous idea, and this bikeway should be replaced. – at San Francisco, CA
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The Valencia center bikeway is causing head-on collisions between people, resulting in serious injuries. Mayor Breed and SFMTA should replace the center bikeway with curbside protected bike lanes or pedestrianization immediately. Please take action now: BetterValencia.com – at San Francisco, CA
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I’ll be at @workshopmlsb at #neurips2023 this Friday and have a PhD internship position in my group this coming summer. Say hi if you are interested! roche.wd3.myworkdayjobs.com/…
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Can I simultaneously hate the Valencia center bike lane while also doubting that the removal of parking spaces on Valencia caused 80% loss of a business on Valencia? Let’s make Valencia one way with a protected bike lane and lots of parking spaces and loading zones!
San Francisco's Amado's Bar Closes, Blames Valencia Bike Lane The San Francisco bar owner said the Valencia Street center-running bike lane forced him to close and is killing small businesses. sfstandard.com/2023/11/30/sa…
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Thanks @SFMTA_Muni. Your design is working as intended.
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Ok, so who is going to train OpenMissense to get them to change their (deep)minds about this?
Interesting excuse... 🤔 hopefully this is not the start of closed source software in the field... "As part of our commitment to releasing our research breakthroughs safely and responsibly, we will not be sharing model weights, to prevent use in potentially unsafe applications."
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What happens to the Valencia Street center cycle track when a vehicle obstructs the driving lane? Exactly what you expect. This wouldn’t happen with curbside protected bike lanes (@BetterValencia), which are better for safety, business, and climate. Please end the “experiment.” – at San Francisco, CA
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SFMTA insists that people on bikes “share the road” with cars on Valencia while SFMTA installs its unprotected center cycle track that’s supposedly “closed.” I followed SFMTA’s guidance; look and see what it got me. The center cycle track is flawed; the rollout is almost worse. – at San Francisco, CA
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This begs the question: what the heck was going on in this studio in the first place?? it’s been seemingly in a state of construction forever
A police car smashed INTO the glass and door front of that studio with the ditch in it on 22nd and Valencia (former Lucca) and there is a motorcyclist on the ground
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The center bike lane on Valencia is already a disaster. The dividers between the bike lane and the car lane are a major hazard to bikers and cars have absolutely no issue going over them and into the bike lane if a car is blocking the car lane - I’ve seen it happen already
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SFMTA is proposing a center bikeway for Valencia Street, sandwiching people on bikes between two lanes of driving cars. Valencia should have parking-protected bike lanes along the curb. Support the vision at actionnetwork.org/letters/va… or send an email using tinyurl.com/ValenciaBikeLane… – at San Francisco, CA
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Why is San Francisco afraid of this? – at San Francisco, CA
One of the most successful pedestrian streets in the world, the Strøget in Copenhagen, was filled with cars until a 2 year 1962 pilot project. The opposition argued “no cars means no business,” but the street has been a massive retail success, the city’s busiest shopping street.
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I’m looking for a summer intern in 2023 for the Computational Structural Biology group at Genentech! Join me in applying AI/ML and other methods to the drug discovery pipeline. We’re open to late stage undergraduates and graduate students. roche.wd3.myworkdayjobs.com/…
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The Computational Structural Biology group @genentech is hiring! Come join us as we build tools to gain deeper insight into protein structure to enable drug discovery. Reach out if you have questions! roche.wd3.myworkdayjobs.com/…
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Jack Nicoludis retweeted
Happy to share my new paper (arxiv.org/abs/2210.04893) with @cwcoley that introduces a new equivariant shape-conditioned generative model, SQUID, for generating chemically diverse 3D molecules in poses that fit a target shape. (1/9)
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Today I start at @genentech as a Senior Scientist in Computational Structural Biology Bioinformatics where I’ll be applying ML/AI methods to protein structure/function and contribute to drug discovery efforts! Im so grateful to all those who helped me during my search! 💙
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Because SF is an amazingly beautiful place and it is incredibly frustrating that our government can’t seem to figure out how to allow more people to live here affordably!
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obviously not saying people should be attacking tenants and residents. but it would be great to have supervisors who would just allow more housing
Jack Nicoludis retweeted
“Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning” Here, structural ensembles are generated using ML, MD, and coevolution. From @DelemotteLab and Drew lab (couldn’t find twitter handle). biorxiv.org/content/10.1101/…
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