Dr. David Barzilai: Can We Reverse Aging? Harvard's Latest Longevity Science Explained | @agingdoc1 youtu.be/P5053hkoXU8

“Can We Reverse Aging?” is our episode title. My answer: not yet with today’s science. Maybe someday. I joined @DarshanShah_MD to discuss slowing aging and extending healthy lifespan. I hope you’ll watch the full conversation. Thanks for your support! youtu.be/P5053hkoXU8

ADHD Drugs May Reduce The Risk of Early Death, Major Study Finds sciencealert.com/adhd-drugs-…

The FOXO-aging axis: Epigenetic insights and chromatin mechanisms “… Chromatin context-specific FOXO targeting may improve anti-aging therapy...” sciencedirect.com/science/ar…

Meningiomas are associated with some birth control Brain tumor risk linked to progestin-based shot is lower than other birth control risks, like blood clots and stroke. braintumorcenter.ucsf.edu/ne…

This chart shows just how rapidly Ebola is spreading No previous Ebola outbreak has grown this quickly. More @voxdotcom: vox.com/future-perfect/50707…

Just one small caveat: let’s not confuse what centenarians believe helped them live so long with what actually did. 🍻

Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep “… tightly synchronized oscillations in norepinephrine, cerebral blood volume, and cerebrospinal fluid (CSF) as the strongest predictors of glymphatic clearance during NREM sleep. ” cell.com/cell/fulltext/S0092…

How high ventilation breathwork alters consciousness: Hypoperfusion, network dynamics, and subjective experience 😵‍💫“High ventilation breathwork (HVB) is increasingly used in psychotherapeutic and contemplative contexts to induce altered states of consciousness (ASC)…” sciencedirect.com/science/ar…

Ubiquitous Sirt1 overexpression is associated with preserved cardiac diastolic function and mitochondrial respiratory capacity in mice on a high-fat diet sciencedirect.com/science/ar…

Ongoing lawsuits allege GLP-1s can cause serious harm. But we don't know how often nprillinois.org/2026-10-10/o…

From self-quantification to predictive ageing: Digital twins as a framework for healthy ageing and longevity 🗣️"A prominent example is the Blueprint project generated by Bryan Johnson (Johnson, 2024), which integrates repeated measurements across metabolic, cardiovascular, inflammatory, functional, imaging and epigenetic domains..."📊 👨‍⚕️Re: @bryan_johnson: "We propose a digital twin framework that models healthy ageing as a latent dynamical system rather than static biomarkers..." sciencedirect.com/science/ar…

Both Doctor and Husband: Longevity Medicine and the Day Prevention Became Personal Re-titled by TEDx: "How conventional and longevity medicine can work together" 🔗youtu.be/DfzlWUwBk4g I'm deeply grateful to the @TEDxBerkshires team for the opportunity to share a story so close to home. As a physician, I've spent years studying how we can prevent illness and help people live longer, healthier lives. My wife's experience made that work personal in a way I never expected. My hope is that this talk encourages people to take a more active role in their health, ask thoughtful questions, and explore what evidence-based prevention can offer alongside conventional medical care. Thank you to everyone who has taken the time to watch. I would love to hear what resonated with you.

"To be happy you must eliminate two things. The fear of a bad future and memory of a bad past" -@TalBenShahar Longevity is my theme here but more time means little if we don’t enjoy it. Savor the present. Cherish the past. And stay optimistic that tomorrow can be even better🌹

Breathwork Really Can Induce an Altered State of Consciousness, Experiment Shows sciencealert.com/breathwork-…

Kyle Kennedy, granddaughter of Robert F. Kennedy, dies at 42 The Kennedy scion suffered a spinal injury in 2020 that “resulted in long term paralysis, disability, and other medical challenges,” her obituary said | @NBCNews nbcnews.com/news/us-news/kyl…

Effects of Finasteride exposure on lifespan and locomotor phenotypes “Finasteride is one of the core medications for treating androgen-associated diseases in men. It exhibits multiple therapeutic functions, including inhibiting 5α-reductase, reducing dihydrotestosterone levels, and improving conditions, including prostate enlargement and hair loss. Using Drosophila as the primary model and a mouse behavioral assay as a complementary approach, we combined developmental and behavioral assessments, morphological analyses of motor and sensory neurons, transcriptomics, and genetic methods to investigate developmental, neuronal, and behavioral changes associated with Finasteride exposure and explore their potential molecular basis. Our results indicate that Finasteride exposure is associated with increased intestinal reactive oxygen species (ROS) accumulation and shortened lifespan in both sexes, together with significantly reduced starvation resistance in males. In addition, Finasteride exposure was also associated with altered neuromuscular junction (NMJ) morphology, reduced locomotor performance, and decreased cask expression. … Overall, this study reveals changes in lifespan and locomotor phenotypes associated with Finasteride exposure and further highlights the importance of investigating its broader biological effects in other experimental systems.” link.springer.com/article/10…

Exercise Prescriptions for Cardiovascular Health in Adults: 2026 ACC Scientific Statement: A Report of the American College of Cardiology sciencedirect.com/science/ar…

Living Longer, but Not Better? @davidasinclair @JoinLifespan lifespan.com/blogs/magazine/…