Assistant Professor @CoulterBME at @GeorgiaTech & @EmoryUniversity via @RagonInstitute @MITEECS & @IITBombay
Atlanta, GA
Joined March 2019
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New preprint up! Our foray into hydrogels. A plug and play booster module for binding assays of all kinds - from plates to microarrays to lateral flows to electronic detection.
biorxiv.org/content/10.64898…
Seems like the BCG vaccine is a gift that keeps on giving. Often in surprising ways. Not feeling too bad about that scar on my arm. 😉
A century-old vaccine against tuberculosis helps to regulate blood sugar in people with diabetes
go.nature.com/4xlRHTb
Aniruddh Sarkar retweeted
Better diagnostics could have limited this Ebola outbreak, says virologist Kevin K. Ariën.
go.nature.com/4x5a12H
Next chapter of our selective/targeted single cell electroporation mediated gene delivery story is out now👇led by Madeline Hoyle & co-authors pubs.rsc.org/en/content/arti…
Regular reminder that his discovery of Mtb was the result of his developing new tools of the trade (e.g immersion lenses & microphotography & even Petri dishes). In that sense he was a bioengineer as well. 😉
On 24 March 1882, German physician and Nobel Prize laureate Robert Koch announced the discovery of the bacterium that causes tuberculosis (TB) - a date marked by #WorldTBDay today.
ALT Robert Koch next to his drawing of tuberculosis bacilli
New cover art for a new paper. One thing this particular chemistry does very reliably - beyond making electronic detection of all kinds of things possible - is generating pretty images under the electron microscope. 😀That's a cell btw - not a desert rose crystal. Paper linked 👇
Electronic Detection of Functional Cellular Immunity Using Enzymatic Metallization | ACS Omega pubs.acs.org/doi/10.1021/acs…
Microfluidic electroporation has existed as a virus-free delivery alternative for decades now (since pre-Jesse Gelsinger gene therapy era almost) & yet even in the cell therapy era why no translational use yet? We review (& opine 😉) here. 1st review article from the lab. 👇
Online now: A critical review of microfluidic electroporation for therapeutic cell engineering dlvr.it/TR94xk
Led by Madeline Hoyle (1st 1st author paper for her - yay!) & co-authored with Julio Arroyo and electroporation guru Rafael Davalos @CoulterBME @gatechengineers
👀Over 50 latent tuberculosis cases detected at SF high school sfgate.com/bayarea/article/t… via @SFGate
Aniruddh Sarkar retweeted
Inexpensive High-Throughput Multiplexed Cytokine Detection for Tuberculosis Diagnostics Using Amplified Enzymatic Metallization
ift.tt/Gd7l5mJ
#biorxiv_bioE
Any time I feel down about the future of the teaching part of my job (given AI etc) I remember how much of an impact teachers like Prof Vasi had on so many of us & it all feels worth doing & doing as best as I can
A proud moment for IIT Bombay!
Former Deputy Director and distinguished academician Prof. Juzer Vasi has been conferred the Padma Shri, in recognition of his extraordinary lifetime contribution to science and engineering. A widely respected name in the field of semiconductors and microelectronics, Prof. Vasi, Department of Electrical Engineering, continues to inspire many as Professor Emeritus.
@PadmaAwards
@IITBAA1
🤯 “Together, these findings suggest that consciously generated positive expectations can engage reward circuitry to influence immune function, a process that may be leveraged for non-invasive immune modulation.”
A new trial provides direct human evidence that the #placeboeffect can shape humoral #immunity, showing that reward-related brain activity correlates with #vaccine induced antibody production and opening new avenues for treating many medical conditions. News & Views from @jonykipnis & colleagues @BIG_CenterWashU
nature.com/articles/s41591-0…
Aniruddh Sarkar retweeted
Excited to share our paper:
“Concurrent TB and HIV therapies control TB reactivation during co-infection but not chronic immune activation” 🎉
nature.com/articles/s41467-0…
Pathogen control ≠ immune recovery → need host-directed therapies in TB/HIV co-infection.
@NatureComms
Freshly uploaded preprint from our lab: A new approach to TB diagnostics - from a drop of blood instead of sputum.
Microscale Multiplexed Antigen-Specific Antibody Fc Profiling for Point-of-Care Diagnosis of Tuberculosis medrxiv.org/content/10.1101/…
Happens in 10mins! I know right after a short lunch break is a tough slot so just reminding folks 👇#BMES2025
If you're in sunny San Diego for #BMES2025 do check out the talks from our lab on Thu & Fri 👇 @CoulterBME @BMESociety
If you're in sunny San Diego for #BMES2025 do check out the talks from our lab on Thu & Fri 👇 @CoulterBME @BMESociety
On the (inside) cover of @LabonaChip this upcoming issue xlink.rsc.org/?DOI=D5LC00042…
New paper from the lab👇Congrats to Spencer Zhang (@GT_BioE PhD student) and co-authors. Here we port our antibody-omics workflow to a easy-to-make (i.e. lithography-free) and easy-to-use (i.e. gravity/capillary flow driven) microfluidic chip.
pubs.rsc.org/en/content/arti…
New NOA (phew!😀): MPI R21 with @LisaMarie_Mtb to use our antibody-omics platform for TB in children affected by HIV. Grateful for the support to continue and extend this important work. @NIAIDNews @NIH
New paper from the lab👇Congrats to Spencer Zhang (@GT_BioE PhD student) and co-authors. Here we port our antibody-omics workflow to a easy-to-make (i.e. lithography-free) and easy-to-use (i.e. gravity/capillary flow driven) microfluidic chip.
pubs.rsc.org/en/content/arti…