@aparnanathan

Single-cell + genetics + teaching @HarvardDBMI • writing @PopSci, @novapbs, @AAASMassMedia/@phillyhealthsci, @DrugDiscovNews and others

 Boston, MA
Joined June 2015
  • Tweets40
  • Following422
  • Followers555
I’m excited to share our latest work on enhancing the power to detect response expression quantitative trait loci (reQTLs) at single-cell resolution across different perturbations conditions: biorxiv.org/cgi/content/shor… with @soumya_boston @broadinstitute and co-authors 👇
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Excited to share a review led by @kalaga27 describing the relationship between human autoimmunity and T cell functional traits! nature.com/articles/s41467-0… @broadinstitute @BrighamResearch @aparnanathan
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Very excited to share our highly collaborative work as part of the @NIH_NIAMS AMP-RA/SLE network. We mapped single cell tissue states in #rheumatoid #arthritis. nature.com/articles/s41586-0…
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Aparna Nathan retweeted
Joyce Kang@joycebkang20 May 2023
Hot off the press! 📢✨ Check out our in-depth review on “Methods and Insights from Single-Cell Expression Quantitative Trait Loci” 🧬📖! @AnnualReviews Had a great time writing with @Raveancic @aparnanathan @nicolesoranzo @soumya_boston annualreviews.org/doi/abs/10…
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Single-cell genomics meets human genetics go.nature.com/3LjdSmL #Review by @AnnaSECuomo, @aparnanathan, @soumya_boston, @dgmacarthur and @drjosephpowell #singlecellgenetics

Single-cell genomics meets human genetics

Nature Reviews Genetics - In this Review, the authors describe the emerging field of single-cell genetics, which lies at the intersection of single-cell genomics and human genetics. They review the...

nature.com
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On July 1, I officially begin my position as Assistant Professor at the University of California San Diego (UCSD) in the Halıcıoğlu Data Science Institute and the Department of Medicine. I'll be recruiting grad students, postdocs, and comp techs! amariutalab.org/
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Excited to see our single-cell eQTL project finally published! It ties together everything I've worked on during my PhD, with a lot of help from @asgari_samira and @Kazu_Ishigaki nature.com/articles/s41586-0…
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Aparna Nathan retweeted
Nieman Lab
@NiemanLab19 Apr 2022
"From building trust with readers to indulging your own curiosity, local reporters share tips for finding science stories for local audiences." nie.mn/391X5UN
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Inspired by my time at @PhillyInquirer this summer, I wrote about local science reporting for @Open_Notebook. Thanks to @sabrinaamorenoo, Mark Johnson, @MoNscience, @swadely, and @amyqin12 for sharing your wisdom theopennotebook.com/2022/04/…

Reporting That Hits Home: Covering Science for Local Audiences - The Open Notebook

Local media outlets often have close ties with their communities, making them unique platforms for informing and empowering readers with science stories that matter for their daily lives. This means...

theopennotebook.com
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And extra thanks to @RachelZamzow @SiriCarpenter and @beecycles for feedback (all @AAASMassMedia alums!)
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1/ Thrilled to share our work presenting the AMP ( @NIH_NIAMS @NIAIDNews) #rheumatoidarthritis single cell resource with @FanZhang_Jessie, @AHelenaJonsson1, @aparnanathan, Kevin Wei, @nghia_millard, many others. biorxiv.org/content/10.1101/… 🧵

Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid...

Rheumatoid arthritis (RA) is a prototypical autoimmune disease that causes destructive tissue inflammation in joints and elsewhere. Clinical challenges in RA include the empirical selection of drugs...

biorxiv.org
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Aparna Nathan retweeted
Yang Luo@yluo869 Feb 2022
📢📢Excited to share our latest work on a genome-to-genome study of tuberculosis to search for associations between human host DNA 🧬 and the genome of the infectious agent Mtb 🦠. Here goes a 🧵 for our key findings: medrxiv.org/cgi/content/shor…
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The Zhang lab @CUMedicalSchool is looking for a talented #postdoc to work on our established project using #machinelearning and #singlecell multi-omics to study immune-mediated disease! Apply at cu.taleo.net/careersection/2…🎉 Send your CV to [email protected] if you are interested
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Highly recommend applying to the AAAS MMF! I had an amazing time at @phillyhealthsci this summer—not only training as a science writer, but also getting insight into how the public engages with science
AAAS Mass Media Fellowship@AAASMassMedia1 Oct 2021
Applications are now open for the 2022 Mass Media Fellowship! If you're a STEM student or postdoc who wants to write about the top science stories next summer, consider applying before January 2nd, 2022! #scicomm Learn more and apply here: fcld.ly/dc02kde

AAAS Mass Media Science & Engineering Fellowship | American Association for the Advancement of...

This 10-week summer program places science, engineering, and mathematics students at media organizations nationwide. Fellows use their academic training as they research, write, and report today’s...

aaas.org
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To hear more about my experience this summer, check out this video from @AmstatNews: youtube.com/watch?v=vSIgjR2I…
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🥳🥳🥳 I will join @SinaiGenHealth & @SinaiGenetics as Ass. Prof. from next year. We will use statistical, population & functional genomics approaches to understand the human genetic basis of infectious diseases. AND we are hiring a postdoc, ping me if interested to chat more.
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Joyce Kang@joycebkang7 Oct 2021
Thrilled to share Symphony, our method for single-cell reference mapping, out now in @NatureComms 🎉: nature.com/articles/s41467-0… @ilyakorsunsky @soumya_boston
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Tom Avril@TomAvril113 Aug 2021
White-tailed deer "might be picking up more than nuts and berries this year," writes @AAASMassMedia's @aparnanathan, in this reminder that zoonosis goes in both ways: inquirer.com/science/deer-co…

Penn State study found COVID-19 in deer and researchers warn Pa. hunters should take precautions

White-tailed deer seemed particularly vulnerable to the virus, as they thrive in suburban and urban areas near human settlements and have similar ACE2 receptors to humans.

inquirer.com
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My other (academic) writing project this summer: our new memory T cell eQTL study, at single-cell resolution!
Soumya Raychaudhuri সৌম্য রায়চৌধুরী@soumya_boston31 Jul 2021
Pleased to share with @aparnanathan our latest on the genetics of gene regulation in T cells, and its dynamic nature: single-cell resolution eQTL study of >500,000 resting memory T cells capturing physiologic states from 259 individuals. biorxiv.org/content/10.1101/…

Modeling memory T cell states at single-cell resolution identifies in vivo state-dependence of...

Many non-coding genetic variants cause disease by modulating gene expression. However, identifying these expression quantitative trait loci (eQTLs) is complicated by gene-regulation differences...

biorxiv.org
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My latest for @PhillyInquirer: diving into new CDC data to figure out what we know about vaccines and variants w/@TomAvril1 @SarahGantz @AAASMassMedia @AmstatNews inquirer.com/health/coronavi…

The delta variant may spread as fast as chickenpox, and other facts about new CDC data

An important component of the CDC document was new data published Friday from a July outbreak in Massachusetts, which CDC Director Rochelle Walensky called “concerning” and “a pivotal discovery.”

inquirer.com
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