@AReginaCabrera

🇬🇹🧬🧫🔬👩🏽‍🔬 Postdoc. Exercise Scientist at University of Arkansas | Molecular Muscle Mass Regulation Lab

Joined March 2023
  • Tweets41
  • Following121
  • Followers94
9Media
Regina_Cabrera retweeted
Kevin Murach@KevinMurachPhDSep 22
“Exercise preconditioning confers skeletal muscle myometaplasticity”. biorxiv.org/content/10.64898… #myotwitter

Exercise preconditioning confers skeletal muscle myometaplasticity

Previously exercise trained skeletal muscle is more growth-responsive to retraining. Using a murine training-detraining-retraining approach and multi-omics, we find that Pecam1 gene expression is...

biorxiv.org
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Our paper was selected for #APSselect by the @APSPhysiology! We are incredibly grateful that our research on cancer- & chemo-induced #cachexia is receiving this recognition. We hope it continues to bring attention to the importance of considering biological sex in muscle research
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Replying to @AReginaCabrera
@AReginaCabrera (@UACachexia @franmorena98 @eleanor_schrems @KevinMurachPhD @STsitkanou @m_ruqaiza) Differential impact of #cancer- and #chemotherapy-induced #cachexia: a comparative analysis in a preclinical model of #colorectalcancer by #biologicalsex ow.ly/9ttH50Zx5UR
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Regina_Cabrera retweeted
Journal of Physiology@JPhysiolJul 22
🎓️ EDITOR'S CHOICE🎓️ In a mouse model of cancer cachexia, Tsitkanou (@UACachexia) et al. show the potential for exercise training not only to mitigate muscle loss, but also to reduce tumour burden. 🔗 buff.ly/UcVWU9k
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Regina_Cabrera retweeted
Stavroula Tsitkanou@STsitkanouJul 26
Excited to see our work selected as an Editor's Choice in @JPhysiol Grateful to all co-authors, PIs @UACachexia @KevinMurachPhD and @PJKoopmansPhD for this great collaboration!
Journal of Physiology@JPhysiolJul 22
🎓️ EDITOR'S CHOICE🎓️ In a mouse model of cancer cachexia, Tsitkanou (@UACachexia) et al. show the potential for exercise training not only to mitigate muscle loss, but also to reduce tumour burden. 🔗 buff.ly/UcVWU9k
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Regina_Cabrera retweeted
Kevin Murach@KevinMurachPhDJun 30
Carried by Dr. @RonaldGJones3, “the gigaMYC paper” as the trainees call it: “Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations”. A huge collab that started many many years ago. Too many to thank! biorxiv.org/content/10.64898…

Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations

Despite decades of study, MYC’s physiological role in adult tissues remains obscured by the models used to investigate it. Most work relies almost exclusively on chronic or constitutive MYC induction...

biorxiv.org
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Regina_Cabrera retweeted
Kevin Murach@KevinMurachPhDMay 2
Best lab ever. #myotwitter
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Okaaaay!! I got a poster presentation award today at @BiochemExercise 😎🥳👩🏽‍🔬
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A HUGE congratulations to all our award winners and thank you to our sponsors!! @APS_Function @Nature_NPJ @APSPhysiology @RNMontalvo @dhood_york @HornbergerLab @FralinBiomed @vtcsom @KevinMurachPhD @RoanokeCollege @ZhenYanLab
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Nice work here from @AReginaCabrera “Transcriptome Disruptions During the Onset and Progression of Colorectal Cancer-Induced Cachexia” #myotwitter journals.physiology.org/doi/…

Skeletal muscle methylome-transcriptome disruptions during the onset and progression of colorectal...

Cancer cachexia is a wasting condition, primarily affecting skeletal muscle, impairing patients’ quality of life, prognosis, and survival. The molecular triggers are incompletely defined, but given...

journals.physiology.org
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New Directions in Muscle Research at the Tornado Alley Muscle Meeting
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A heavy lift from a literal strongman, PhD candidate @PJKoopmans “The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus” 💪🏻 biorxiv.org/content/10.1101/…

The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus

A detailed analysis of how muscle fiber nuclei (myonuclei) respond to a hypertrophic stimulus would provide a critical step toward understanding compromised skeletal muscle plasticity with age. We...

biorxiv.org
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A new paper from our lab is out! @UACachexia In collaboration with the great @snoke_phd This systematic review of cancer cachexia clinical trials over the past 29 years reveals the need for more inclusive study populations. link.springer.com/epdf/10.11…
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Excited for this project being off the press this morning! Our study showed that the mitochondrial antioxidant SkQ1 may attenuate tumor-induced muscle loss in males while improving muscle contractility in tumor-bearing female mice.
UA Cachexia Lab@UACachexia30 Sep 2024
Fresh out in @AJPCellPhys and off the presses from lead author @STsitkanou with @Franmorena98 @AReginaCabrera @eleanor_schrems @SeongLim7 @ChrisPerryMito @KevinMurachPhD and more! journals.physiology.org/doi/…

Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves...

Mitochondrial dysfunction is a hallmark of cancer cachexia (CC). Mitochondrial reactive oxygen species (ROS) are elevated in muscle shortly after tumor onset. Targeting mitochondrial ROS may be a...

journals.physiology.org
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Congrats Dr. @Franmorena98 👏🏽 keep fighting and conquering all battles (hehe) good job! 💪🏽
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From our Mechanisms Underlying Diversity in #Cancer #Cachexia collection comes, Exploring Heterogeneity: A Dive into Pre-Clinical Models of Cancer Cachexia (Francielly Morena da Silva et al. @UARKHHPR): ow.ly/5eG150SyX94
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Sunny day at Limerick! 🇮🇪☀️ recharging science motivation 👩🏽‍🔬🔋 #ibec2024
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Regina_Cabrera retweeted
UA Cachexia Lab@UACachexia10 Jun 2024
Out ahead of press today in @AJPCellPhys! @Franmorena98 and @AReginaCabrera explore heterogeneity in cancer cachexia in preclinical models! Check it out! Part of an outstanding call for papers for mechanisms underlying diversity in cancer cachexia. journals.physiology.org/doi/…

Exploring heterogeneity: a dive into preclinical models of cancer cachexia | American Journal of...

Cancer cachexia (CC) is a multifactorial and complex syndrome experienced by up to 80% of patients with cancer and implicated in ∼40% of cancer-related deaths. Given its significant impact on...

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Regina_Cabrera retweeted
Deena Snoke@snoke_phd12 Feb 2024
Happy belated international day of women and girls in science! #WomenInSTEM To celebrate, we are excited to announce the formation of a new @CancerCachexia interest group, Women in Cachexia (#WCX). @aneesha_dg @BrittCounts @paige_arneson 🎉👩‍🔬🧵
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Regina_Cabrera retweeted
Bradley Gordon@bradgordon726 Feb 2024
The mechanosensitive gene Arrestin domain containing 2 regulates myotube diameter with direct implications for disuse atrophy with aging | American Journal of Physiology-Cell Physiology journals.physiology.org/doi/… I don’t self promote, but Grant Laskin’s work warrants recognition.

The mechanosensitive gene arrestin domain containing 2 regulates myotube diameter with direct...

Arrestin domain containing 2 and 3 (Arrdc2/3) are genes whose mRNA contents are decreased in young skeletal muscle following mechanical overload. Arrdc3 is linked to the regulation of signaling...

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