@ariabdullah1978

Surgical Pathologist, loving mother nature

Joined August 2014
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383Media
Animated tram truck appearance of papillary thyroid carcinoma, tall cell variant
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#PathArt I made this a while back when I was doing GIT..
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Which organ is it, what's the IHC, and what are the differentials? #PathX
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Young boy with a tongue mass, can't be any more clear, or should I say granular!!? #PathX
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One of its kind: 53 F, breast mass with axillary LN, triple negative GATA3, GCDFP15, mammaglobin and CK7 positive P63, P40, calponin, S100, SOX10 Negative Ki67 10% While P40 positive in axillary LN #PathX #BreastPath Set 1:
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Set 2: LN
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Set 3: Some IHC
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Middle age lady with endobronchial mass #PathX
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70 F, breast mass, signed out as invasive cribriform carcinoma in original lab IHC: Positive: AE1/AE3, SOX10, S100 and MUC4 Negative: HMWCK, ER, PR, HER2, synaptophysin, CD56, TRPS1, GATA3, DOG1, Calponin, P63, chromogranin, p40 Ki67 5% What to add next? Thoughts Set1:
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Set 2: IHC is SOX10
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Set 3: IHC S100 and MUC4
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I recently reviewed the pathology library archives and discovered these vintage virtual learning slides of old times from earlier period..oldies and goldies
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A middle-aged lady patient presenting with multiple bilateral thyroid nodules and cervical lymph node metastases, if restricted to a single marker, which would be your selection? And what is your diagnosis Last image is from the LN #PathX
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Calcitonin IHC
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If I tell you this is synaptophysin, what will be your second marker?
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Middle-aged female with goiter and hypothyroidism, 0.8 cm irregular whitish mass. What are your thoughts about it, what are the differential diagnoses, and what IHC would you order? #PathX Set 1:
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Sorry for being late regarding update about this case: Positive IHC: PAX8, TTF1, thyroglbulin, BRAF, p63 (focal) Negative: beta catenin, Pan-TRK, CDX2, CD10 Diagnosis is PTC-SD Why not anaplastic? As it is small, confined to thyroid, no necrosis no brisk or abnormal mitosis
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Typical PTC nuclear features are obvious in these areas with colloid in the lumen Behaviour of PTC-SD is not well known so far
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Set 2:
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