Director- UM Natural Products Discovery Core: Discovery of drug leads and alteration of their biosynthetic pathway is what I do but tweets are just emojis :-)
Ann Arbor, MI, USA
Joined September 2009
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Ashu Tripathi retweeted
The U-M Natural Products Discovery Core's pitch video for developing a rapid-response system for agricultural biodefense has been deemed Awardable by the @DARPA ERIS Marketplace.
Government customers can view the 7-minute video solution on ERIS: darpaconnect.us/eris.
“We are excited about the opportunities that this recognition on the DARPA ERIS Marketplace opens, and eager to help transform agricultural defense from reactive to proactive,” says NPDC Director @ashumich .
ALT DARPA Awardable badge with text: The University of Michigan's Natural Products Discovery Core has achieved "Awardable" status through the DARPA ERIS Marketplace for its proposal to develop AI-accelerated microbial countermeasures against agricultural threats."
Please help with this fundraiser. Your donation will make a meaningful difference in advancing STEM education for elementary/middle school students. We are deeply grateful for your commitment to inspiring the next generation of scientists and innovators. gofund.me/4467a03e
Ashu Tripathi retweeted
Recent Beamish award winner @TaoThuan @NatMetabolism @UBC describes how to avoid “nonsensical” results in metabolomics
doi.org/10.1038/s42255-025-0…
A very well deserved professorship!
Congratulations to Dr. Amanda Garner, who has been named Charles Walgreen, Jr. Professor of Medicinal Chemistry.
This named professorship recognizes Dr. Garner's dedication to science, education and mentorship. Read the full release: bit.ly/4c4k4La
ALT Portrait of Amanda Garner, PhD, a Professor of Medicinal Chemistry, smiling in an office setting.
Beautiful study!
Thrilled to share our discovery of a novel polyene macrolide antifungal with a unique mechanism of action—targeting fungal membrane phospholipids. Grateful for the collaboration with Prof. Zongqiang Wang’s team at CPU. Check out our paper in @Nature: nature.com/articles/s41586-0…
Hopefully smart people can use some analytics into making funding decisions to NIH 🤷🏽
fiercebiotech.com/research/n…
The @ScienceMagazine paper, "Efficient discovery of natural products through native strain metabolomics", highlights a cutting-edge approach combining metabolomics, genome mining, and mass spectrometry to unlock microbial chemical diversity.
science.org/doi/10.1126/scie…
🌱 Exciting news for #NaturalProducts enthusiasts! The ACS Virtual Special Issue explores the latest breakthroughs in natural products & #MedicinalChemistry, shaping the future of #DrugDiscovery. Don't miss out on these cutting-edge insights!Read more: pubs.acs.org/page/vsi/natura…
All the NP discovery resources put together effectively by @kate_duncan and team!
actinobase.org/index.php?tit…
A top-down drug discovery (TD3) approach, starting with a massive digital search through a database of over 100,000 fully genomicized fungi to identify loci encoding molecules with a predetermined human target by #LifeMine
pubs.acs.org/doi/10.1021/acs…
Well..well! I am on Metformin for 11 yrs now, could have studied its impact on me. Never too late I guess 😀
cell.com/cell/abstract/S0092…
Painstakingly create the BGC in chemdraw/bio render etc. or just use RAIChU by @marnixmedema?
link.springer.com/article/10…
This is a terrific framework! nature.com/articles/s41597-0…
Excited to announce our latest paper with #Burkartlab! We uncovered the cryptic cerulenin rearrangement in ketosynthase inhibition using advanced NMR & MS. A leap forward in drug development! pubs.acs.org/doi/full/10.102…
Excited to share our collaborative study with #MohimaniGroup at @CarnegieMellon
nature.com/articles/s41467-0…
Congratulations @ColleenYancey for the great study! I am awaiting further exciting follow ups from @laurenhart_98
Excited to see
@ColleenYancey and I's (among many coauthors @GreatLakesGreg @davidhsumich @ashumich) joint effort out now! Spoiler alert that these bugs are capable of producing much more than microcystins...
doi.org/10.1128/msystems.003…
This what I call direct intervention in natural evolution 🤦🏻♂️
pbs.org/newshour/nation/u-s-…
SMIRC approach for potentially isolating novel natural products straight from nature. I would like to use the technique to figure out random chemicals spread across our vicinity. nature.com/articles/s41467-0…
