@badbrainstrains

Board-certified Neuropathologist and Molecular Genetic Pathologist, Henry Ford Health

 Detroit, MI
Joined December 2015
  • Tweets1.3K
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404Media
A couple months late on this one but the NIH DNA methylation conference reminded me: pubmed.ncbi.nlm.nih.gov/4261…
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The HFH pathology residents and medical students put at least 20 abstracts into USCAP. That’s a lot of hard work on top of a lot of hard work. I love that it’s all outside my office.
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D1/D5 agonist that may be combined with levodopa to increase on time. michaeljfox.org/news/fda-app…

FDA Approves Tavapadon for Parkinson’s Motor Symptoms

Tavapadon (Juvmo) is a new once-daily pill for Parkinson’s motor symptoms. Here’s how it works, who it may help and what to discuss with your doctor.

michaeljfox.org
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Phase 3 ROADS trial shows resection and tile-based radiation therapy (TBRT) demonstrated superior tumor control and significantly longer survival compared to standard of care (R+SRT in newly diagnosed operable brain mets. ascopubs.org/doi/10.1200/JCO…

Surgery and tile-based radiation therapy versus surgery and stereotactic radiation for newly...

PURPOSEPost-operative stereotactic radiation (SRT) is the standard-of-care for resected brain metastases. Implantation of cesium-131 collagen tiles (tile-based radiation therapy, TBRT) initiates...

ascopubs.org
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Updates on diagnostic and prognostic molecular biomarkers of CNS tumors neurotherapeuticsjournal.org…

“Updates on diagnostic and prognostic molecular biomarkers of CNS tumors”

The diagnosis and classification of central nervous system (CNS) tumors has undergone a paradigm shift over the past decade, evolving from a purely histology-based approach to an integrated framework...

neurotherapeuticsjournal.org
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Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes onlinelibrary.wiley.com/doi/…

Brain Pathology | ISN Neuropathology Journal | Wiley Online Library

In this study including 31 circumscribed meningeal melanocytic neoplasms (melanocytoma, intermediate-grade melanocytic tumor [IMT], and melanoma), overall survival (OS) differed significantly among...

onlinelibrary.wiley.com
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Happy to announce a partnership with the SPHMMC Department of Pathology in Addis Ababa and Morphle Labs as well as to receive this CAP Foundation Global Pathology Development Grant!
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ASD interactome mapping for 250 high risk genes in human organoids and Xenopus embryos. science.org/doi/10.1126/scie…

Autism mutations rewire protein interaction networks to drive neurodevelopmental pathology

Systematic mapping of protein-protein interaction (PPI) networks and determining how causal mutations rewire them in autism spectrum disorder (ASD) provide a powerful framework for uncovering disease...

science.org
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As part of the HFH+MSU partnership I have been appointed as an assistant professor at Michigan State University!
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North American and international pathology meetings for 2026/2027...
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...with physician scientist meetings and closed 2026 meetings.
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It was also fun and a privilege to speak to high school students this morning as part of the RYSE MED summer program at HFH.
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It is always fun and an honor to share some time with medical students and path interest groups. WSUSOMPSIG was great!
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When a bad batch of reticulin causes temporary send outs and the new batch solves the problem:
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I now have my cybertronian AI companion (Perceptor and Magnificus) diagnostic team installed in the office. I think I may have been groomed as a physician 👨‍🔬 scientist…🤖
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Congrats to our resident Priti Agarwal and my colleague Olena Kis on our ASCP CAP-ACP 2026 abstract submission! Enjoy Montreal!
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PLAG1 driven brain tumor following IDUA AAV gene therapy… science.org/content/article/…

Boy’s brain tumor tied to gene therapy

Researchers report first cancer caused by virus widely used to deliver genes, but say risk is low

science.org
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We were delighted to run an informatics/AI enhanced neuropathology workshop last Saturday from 9-2 for Michigan State University and Wayne State University medical students (path interest groups) Thanks to the HFH and the path dept! #HenryFordHealth #pathology #neuropathology
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I hope there are a high number of responses for this CAP survey seeking input on pathology outreach in low resource settings. Due April 15th! #pathology docs.google.com/forms/d/e/1F…

SURVEY CAP Foundation Impact Trip Grant

We are seeking your input regarding the following opportunity: CAP Foundation Impact Trip Grant This grant supports US-based pathologists who are interested in volunteering for short-term opportuni...

docs.google.com
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It's always nice to be able to present something for the AANP meeting! Reminder that trainees can attend for $50. We will be presenting our work in progress at characterizing "Glioblastoma Survival with Partial Gains and Losses in Chromosomes 7 and 10 at Henry Ford Health."
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