@bbbpapers

Daily RSS feed for #bbb papers in #PubMed. Image of brain coral from http://t.co/o0Vvn7k8ep…

Joined February 2014
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Environmental aluminum oxide inducing neurodegeneration in human neurovascular unit with immunity dlvr.it/T157sr

Environmental aluminum oxide inducing neurodegeneration in human neurovascular unit with immunity -...

Aluminum oxide nanoparticle (AlNP), a ubiquitous neurotoxin highly enriched in air pollution, is often produced as an inevitable byproduct in the manufacturing of industrial products such as cosmet...

pubmed.ncbi.nlm.nih.gov
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NIR-promoted ferrous ion regeneration enhances ferroptosis for glioblastoma treatment dlvr.it/T157sk

NIR-promoted ferrous ion regeneration enhances ferroptosis for glioblastoma treatment - PubMed

Ferroptosis, a unique iron-dependent mode of cell death characterized by lipid peroxide accumulation, holds significant potential for the treatment of glioblastoma (GBM). However, the effectiveness...

pubmed.ncbi.nlm.nih.gov
260
Th17 cell promotes apoptosis of IL-23R+ neurons in experimental autoimmune encephalomyelitis dlvr.it/T157sc

Th17 cell promotes apoptosis of IL-23R+ neurons in experimental autoimmune encephalomyelitis -...

Myelin antigen-reactive Th1 and Th17 cells are critical drivers of central nervous system (CNS) autoimmune inflammation. Transcription factors T-bet and RORγt play a crucial role in the differentia...

pubmed.ncbi.nlm.nih.gov
175
Blood-brain barrier damage associates with glia-related cytokines in the cerebrospinal fluid of patients with Multiple Sclerosis dlvr.it/T157sD

Blood-brain barrier damage associates with glia-related cytokines in the cerebrospinal fluid of...

BBB damage in MS is linked to a specific CSF cytokines pattern (CXCL-9, CXCL-10, IL-16), that are also involved in astrocyte-microglia interaction. To what extent their continuous production in the...

pubmed.ncbi.nlm.nih.gov
187
Unveiling the regulatory role of miRNAs in stroke pathophysiology and diagnosis dlvr.it/T13tWB

Unveiling the regulatory role of miRNAs in stroke pathophysiology and diagnosis - PubMed

Stroke, a major global cause of mortality, leads to a range of problems for those who survive. Besides its brutal events, stroke also tends to have a characteristic of recurrence, making it a complex...

pubmed.ncbi.nlm.nih.gov
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Blood-brain borders: a proposal to address limitations of historical blood-brain barrier terminology dlvr.it/T12XTt

Blood-brain borders: a proposal to address limitations of historical blood-brain barrier terminol...

Many neuroscientists use the term Blood-Brain Barrier (BBB) to emphasize restrictiveness, often equating or reducing the notion of BBB properties to tight junction molecules physically sealing...

pubmed.ncbi.nlm.nih.gov
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Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer's disease dlvr.it/T12XTp

Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal...

Breakdown of the neurovascular unit is associated with blood-brain barrier (BBB) leakiness contributing to cognitive decline and disease pathology in the early stages of Alzheimer's disease (AD)....

pubmed.ncbi.nlm.nih.gov
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Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases dlvr.it/T12XTm

Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases - PubMed

Despite the increasing global incidence of brain disorders, achieving sufficient delivery towards the central nervous system (CNS) remains a formidable challenge in terms of translating into improved...

pubmed.ncbi.nlm.nih.gov
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Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice dlvr.it/T12XTg

Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive...

Risk factors contributing to dementia are multifactorial. Accumulating evidence suggests a role for pathogens as risk factors, but data is largely correlative with few causal relationships. Here, we...

pubmed.ncbi.nlm.nih.gov
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Microbial transmission in the social microbiome and host health and disease dlvr.it/T12XTP

Microbial transmission in the social microbiome and host health and disease - PubMed

Although social interactions are known to drive pathogen transmission, the contributions of socially transmissible host-associated mutualists and commensals to host health and disease remain poorly...

pubmed.ncbi.nlm.nih.gov
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Overcoming brain barriers through surface-functionalized liposomes for glioblastoma therapy; current status, challenges and future perspective dlvr.it/T110BW

Overcoming brain barriers through surface-functionalized liposomes for glioblastoma therapy;...

Glioblastoma (GB) originating from astrocytes is considered a grade IV astrocytoma tumor with severe consequences. The blood-brain barrier (BBB) offers a major obstacle in drug delivery to the brain...

pubmed.ncbi.nlm.nih.gov
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Differential transcriptome response of blood brain barrier spheroids to neuroinvasive Neisseria and Borrelia dlvr.it/T10HCF

Differential transcriptome response of blood brain barrier spheroids to neuroinvasive Neisseria and...

The self-assembling spheroids were used to perceive the BBB response to neuroinvasive pathogens - Neisseria and Borrelia. Compromised integrity of spheroids during Neisseria and Borrelia infection as...

pubmed.ncbi.nlm.nih.gov
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Retraction: 1, 25-D3 protects from cerebral ischemia by maintaining BBB permeability via PPAR-γ activation dlvr.it/T10HBw

Retraction: 1, 25-D3 protects from cerebral ischemia by maintaining BBB permeability via PPAR-γ...

[This retracts the article DOI: 10.3389/fncel.2018.00480.].

pubmed.ncbi.nlm.nih.gov
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Schiff-Base Cross-Linked Poly(2-oxazoline) Micelle Drug Conjugates Possess Antiferroptosis Activity in Numerous In Vitro Cell Models dlvr.it/T10H96

Schiff-Base Cross-Linked Poly(2-oxazoline) Micelle Drug Conjugates Possess Antiferroptosis Activity...

A great deal of nanocarriers have been applied to induce ferroptosis in cancer research, yet there are limited examples of nanocarrier formulations to rescue ferroptosis, which can be applied to...

pubmed.ncbi.nlm.nih.gov
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Protective effects of Tinospora cordifolia miers extract against hepatic and neurobehavioral deficits in thioacetamide-induced hepatic encephalopathy in rats via modulating hyperammonemia and glial cell activation dlvr.it/T0zfmk

Protective effects of Tinospora cordifolia miers extract against hepatic and neurobehavioral...

This study revealed promising insights on the protective effects of TC against HE. The findings clearly demonstrated that the significant inhibition of MAPK/NF-κB signalling and glial cell activation...

pubmed.ncbi.nlm.nih.gov
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Sex, hormones and cerebrovascular function: from development to disorder dlvr.it/T0zfmZ

Sex, hormones and cerebrovascular function: from development to disorder - PubMed

Proper cerebrovascular development and neurogliovascular unit assembly are essential for brain growth and function throughout life, ensuring the continuous supply of nutrients and oxygen. This...

pubmed.ncbi.nlm.nih.gov
60
Methotrimeprazine is a neuroprotective antiviral in JEV infection via adaptive ER stress and autophagy dlvr.it/T0zfm6

Methotrimeprazine is a neuroprotective antiviral in JEV infection via adaptive ER stress and...

Japanese encephalitis virus (JEV) pathogenesis is driven by a combination of neuronal death and neuroinflammation. We tested 42 FDA-approved drugs that were shown to induce autophagy for antiviral...

pubmed.ncbi.nlm.nih.gov
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Breast Cancer Brain Metastases: Achilles' Heel in Breast Cancer Patients' Care dlvr.it/T0ymH2

Breast Cancer Brain Metastases: Achilles' Heel in Breast Cancer Patients' Care - PubMed

Brain metastases (BM) significantly affect the prognosis as well as the quality of life of breast cancer (BC) patients. Although advancements in neurosurgical and radiotherapy techniques improve...

pubmed.ncbi.nlm.nih.gov
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Cholesterol dependent cytolysins and the brain: Revealing a potential therapeutic avenue for bacterial meningitis dlvr.it/T0ymFw

Cholesterol dependent cytolysins and the brain: Revealing a potential therapeutic avenue for...

Bacterial meningitis is a catastrophic nervous system disorder with high mortality and wide range of morbidities. Some of the meningitis-causing bacteria occupy cholesterol dependent cytolysins...

pubmed.ncbi.nlm.nih.gov
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Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models dlvr.it/T0ymDV

Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's...

Alzheimer's disease (AD) is characterized by the accumulation of aggregated amyloid peptides in the brain parenchyma and within the walls of cerebral vessels. The hippocampus-a complex brain struct...

pubmed.ncbi.nlm.nih.gov
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