Connectomics, neuroscience, data science, open science | Scientist @AllenInstitute | Formerly @JHUBME PhD w/ @neuro_data, @UW, @MSFTResearch | 🚲 🐦 🏔

Seattle, WA
Joined August 2018
Our work studying the connectome of an insect brain, that of a Drosophila larva, is out today in Science! science.org/doi/10.1126/scie… Some highlights below and in @WindingMichael’s thread. Work with @neuro_data, Carey Priebe, @albertcardona, @ZlaticLab, and many others.
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Fun fact: Seattle's transportation levy, Prop 1 now has over 250,000 yes votes. That's more than any Seattle level politician. And it won in almost every neighborhood across the city — take a look at this map. Talk about a mandate!
Prop 1 winning in a landslide! Seattleites want to invest in a safe, sustainable, and accessible transportation system for everyone. Thank you to everyone who worked on the campaign
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Calling all undergrad neuroscience educators! 🍎🧠 Join our virtual workshop on Nov. 8 for a sneak peek at the new “Neurons Beyond the Textbook” curriculum, including teaching tips, virtual lab tour, and Q&A with neuroscientists. 🎟️ RSVP by Nov. 4. alleninstitute.org/events/ne…
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If you share the vision for a Seattle where everyone can walk, bike, roll, and take transit to where they need to go 🗳️ VOTE FOR Prop 1! Rejecting it does NOT help. The likely outcome is a much worse levy. A bigger yes vote will tell elected leaders to do more for transportation.
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Dream PhD opportunity!
Looking for a PhD position in comparative connectomics? Apply for a joint-supervised position, with myself and @neuroluci. The aim is to understand how circuits evolve by comparing whole-brain connectomes of fruit fly species. Apply for Project #2 here: crick.ac.uk/careers-study/va…
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Our scientists developed the MICrONS Explorer, a virtual observatory of the cortex, to support #neuroscience discovery 🧠🔭 microns-explorer.org This #opendata portal includes #electronmicroscopy-based reconstructions of circuitry from mouse visual cortex. #OpenScienceWeek
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The lab continues to grow, and we are #hiring! Come work with us as a postdoc or technician. Positions are fully funded and flexible in scope. There are so many cool things to do!
The Kebschull Lab is #hiring! Join us @JHUBME to build new multi-omic barcoding tools and to use them to understand brain evolution, aging, and drugs of abuse! We have fully funded positions available!
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Check out the MICrONS Explorer - a virtual observatory of the cortex: microns-explorer.org This #OpenScience data portal includes #ElectronMicroscopy based reconstructions of cortical circuitry from mouse visual cortex.
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Come join us -- some really cool things are happening in lab.
Postdoc in Neuroscience and Tool Development -- Kebschull Lab @JustusKebschull Join the Kebschull lab at @JHUBME as a postdoc to develop new barcoding tools and to understand brain evolution, neurodegeneration, and drugs of abuse jobrxiv.org/job/johns-hopkin… jobrxiv.org/job/johns-hopkin…
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Researchers at @UWMedicine have created a wiring diagram of the motor circuits in the central nervous system that control muscles in fruit flies. This connectome provides detailed information on how the nerve coordination of legs vs. wings differs. 🪰: bit.ly/3RJBP9W
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This one is very close to my heart, proudly sharing our newest preprint “Comparative connectomics of the descending and ascending neurons of the Drosophila nervous system: stereotypy and sexual dimorphism”. A short summary of this project that was 4 years in the making:
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Ben Pedigo retweeted
Results are in for the Visual Columns Mapping Challenge. Congratulations to winner David García-Soriano! 4 contenders improved the benchmark mapping from Codex. Results: codex.flywire.ai/app/visual_… Next challenge coming summer '24. Sign up to be notified: docs.google.com/forms/d/e/1F…
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Today I'm launching Close, an interactive map that shows walkable, bikeable, and transit-friendly neighborhoods across every block in the United States. Try it out: close.city/
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Ben Pedigo retweeted
Do you love big data and the brain? We have #ScienceJobs for you! In Drosophila there are >11,000 cell types that define the circuit structure of the connectome – but we don't know their molecular identity. Integrating connectomes and transcriptomes would be revolutionary. RT 1/3
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We have an opening for a postdoctoral clinical fellow. Candidates should have a PhD + clinical degree (medical, veterinary, etc.) with previous clinical post. Help us study how genes related to psychiatric disorders affect brain wiring and social behaviour! Apply by 30 April...
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My latest #neuro #visualization: An intuition pump on connectivity in the #brain ~75K #neurons in the #MICrONS mm³. I/O segregated by layers, function is columnar; the cortical column is the unit of cortical computation. A typical #pyramidal cell has over >10K input #synapses.
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Really really important work by Max Shinn to shine a light on how PCA can show oscillatory components from noise. A definite must-read for anyone in neuroscience. Phantom oscillations in principal component analysis | PNAS pnas.org/doi/10.1073/pnas.23…
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Our scientists leveraged a massive #openscience #electronmicroscopy dataset to investigate the arguably most studied excitatory neuron in the neocortex: extra telencephalic (ET) neurons, to better understand the complete list of their synaptic partners. biorxiv.org/content/10.1101/…
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