@carway2nar

this is a personal account but I do science

 Chicago, IL
Joined September 2015
  • Tweets1.3K
  • Following139
  • Followers130
83Media
My first first-author paper is out! It was an amazing collaborative effort with a lot of amazing people including @ArvindSPillai1 and @JoeThorntonLab. Please read if you like things involving evolution and biochemistry. pnas.org/doi/10.1073/pnas.24…
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Absolutely phenomenal work from a phenomenal scientist and friend. Take a read if you are into all things protein and Allostery.
Arvind S Pillai@ArvindSPillai114 Aug 2024
Excited to announce our new paper on designing allosterically regulated protein assemblies from scratch, now published in @Nature! This collaborative effort included key contributions from @FloPraetorius, Abbas Idris, @AnnikaPhilomin, @cweidle1 and others! nature.com/articles/s41586-0…

De novo design of allosterically switchable protein assemblies

Nature - We investigate the de novo design of allostery and suggest that it can arise from global coupling of the energetics of protein substructures without optimized allosteric communication...

nature.com
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Excited to share a new preprint we just released on the de novo design of allosterically controllable protein assemblies biorxiv.org/content/10.1101/…

De novo design of allosterically switchable protein assemblies

Allosteric modulation of protein function, wherein the binding of an effector to a protein triggers conformational changes at distant functional sites, plays a central role in the control of metabo...

biorxiv.org
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This is so awesome. Thank you @ATJCagan
Alex Cagan@ATJCagan25 Jul 2023
Carlos Cortez on simple mechanisms for the evolution of heterospecificity in the hemoglobin complex #smbe23 #smbe2023
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Congratulations to the SMBE Graduate Student Excellence Award Winners 2023: Carlos R. Cortez-Romero University of Chicago, USA @carway2nar Simple mechanisms for the evolution of heterospecificity in the hemoglobin complex #SMBE23 @SMBEmeetings
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So honored to have been selected! To all attending #smbe2023, I can’t wait to share my work with you.
Society for Molecular Biology and Evolution@OfficialSMBE21 May 2023
Congratulations to the SMBE Graduate Student Excellence Award Winners 2023! Join us for the GSE symposium during #SMBE2023 in Ferrara, Italy in July smbe2023.org/
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Congratulations to the Graduate Student Excellence award winners, outstanding group of speakers for the symposium in Ferrara!
Society for Molecular Biology and Evolution@OfficialSMBE21 May 2023
Congratulations to the SMBE Graduate Student Excellence Award Winners 2023! Join us for the GSE symposium during #SMBE2023 in Ferrara, Italy in July smbe2023.org/
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Congratulations to the SMBE Graduate Student Excellence Award Winners 2023! Join us for the GSE symposium during #SMBE2023 in Ferrara, Italy in July smbe2023.org/
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Carlos Cortez retweeted
bioRxiv@biorxivpreprint20 Nov 2021
Adaptive ratchets and the evolution of molecular complexity biorxiv.org/cgi/content/shor… #bioRxiv
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Carlos Cortez retweeted
JoeThornton@JoeThorntonLab2 Sep 2021
We are hiring 1-2 postdocs in molecular evolutionary biology / evolutionary biochemistry. Strong support for creativity and independence. Constantly working to be inclusive and supportive. More below and at thorntonlab.org. DM me to discuss. RT please! 1/5
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Carlos Cortez retweeted
JoeThornton@JoeThorntonLab4 Jun 2021
Our new paper on experimental evolution of reconstructed ancestral proteins: Historical contingency is the dominant factor in evolution of protein sequence variation, even under strong selection. Out today in @eLife. 1/ elifesciences.org/articles/6…

Contingency and chance erase necessity in the experimental evolution of ancestral proteins

Replicating experimental evolution from ancestral proteins shows that historical contingency steadily overwhelms chance and necessity as the primary cause of evolutionary variation in molecular...

elifesciences.org
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Submitted my HHMI Gilliam Fellowship application today! No matter what happens I am proud of myself for giving it my all.
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Congrats Georg!
Georg Hochberg@KaHochberg9 Dec 2020
Our paper on a hydrophobic ratchet that preserves useless molecular complexity is out in Nature today. I am excited and nervous in equal parts. A not so short thread on what we found. nature.com/articles/s41586-0…
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Read the new Thornton Lab paper in Nature today! (Our lab is full of some absolutely astounding scientists)
JoeThornton@JoeThorntonLab9 Dec 2020
Our new paper on the evolutionary persistence of useless molecular complexes, out today in @nature. 1/6 nature.com/articles/s41586-0…
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We just published this cautionary tale about ancestral protein reconstruction and evolutionary biochemistry. science.sciencemag.org/conte…
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Carlos Cortez retweeted
Georg Hochberg@KaHochberg20 Nov 2020
We wrote this about a recent ASR article. A quick thread follows below on what I think we can learn from it. science.sciencemag.org/conte…
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nature.com/articles/s41586-0… Hey! I almost never post on twitter about my science stuff but here is a new Nature article that I’m on that talks about how hemoglobin evolved from a monomer to a heterotetramer!
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WHAT??? RIP THE GOAT
TMZ
@TMZ26 Jan 2020
BREAKING: Kobe Bryant Has Died In A Helicopter Crash tmz.me/R5I92Xb

Celebrity News | Entertainment News | TMZ.com

Get everything TMZ in the palm of your hand -- from 24/7 exclusives and breaking celebrity news to the hottest videos and galleries Plus ... watch "TMZ Live", "TMZ Sports" and clips from "TMZ" TV...

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15 of us (Bio & Phys Science Ph.D students) are at #SACNAS to help you get into graduate school. We are here because people helped us succeed. Let us do the same for you. DM us and let us know what time you’d like to chat. To reach as many as possible, please RT! #2019SACNAS
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