Congratulations to @phillipzhou24, Minja Velimirovic
@TiannnYuu, @SherwoodLab on this impressive project!
LDLR variants are the most common cause of inherited high cholesterol, but we don’t know which are harmful. We used prime editing to measure >5,000, out now in @CircAHA, led by @phillipzhou24, Minja Velimirovic & @TiannnYuu with @CassaLabBWH 🧵
ahajournals.org/doi/10.1161/… (1/15)
Chris Cassa retweeted
LDLR variants are the most common cause of inherited high cholesterol, but we don’t know which are harmful. We used prime editing to measure >5,000, out now in @CircAHA, led by @phillipzhou24, Minja Velimirovic & @TiannnYuu with @CassaLabBWH 🧵
ahajournals.org/doi/10.1161/… (1/15)
Chris Cassa retweeted
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at @Columbia & academic career... 1/🧵
Chris Cassa retweeted
Every city or county with a commitment to Vision Zero should have an ad like this playing in their local market.
xitter.cf/Romata331031/status/18…
Chris Cassa retweeted
I don’t understand why you object to me burning your house down, you admit it isn’t perfect. Isn’t this a chance to rebuild it better?
Chris Cassa retweeted
98% of NIH grants that should have gone out this month, didn't. Despite court orders 'unfreezing' the funds, they are frozen. Biomedical research will grind to a halt. Clinical trials will end. All for no reason: the total impact on the US budget is miniscule
Chris Cassa retweeted
Replying to @Boenau
The Battle Tank has better visibility than the Dodge Ram and GMC Sierra.
Chris Cassa retweeted
3-million square feet of asphalt could be converted to a new mixed-use neighborhood after the Mall Road rezoning plan was approved by Burlington Town Meeting this week.
"It's our choice for smart growth. That's huge. Because we understand the economic benefit."
📍Burlington, MA
Chris Cassa retweeted
Excited to share our new network-based rare variant association test, NERINE. If you have a gene-module and want to know how the module affects the trait as well as what the role of each individual gene is, give our method a try! #genetics #stats #BRCA #MI #CAD #Parkinson
NERINE reveals rare variant associations in gene networks across multiple phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in ... biorxiv.org/cgi/content/shor… #biorxiv_genetic
Cities are turning their waterfronts into open space for people. It would be amazing if we did it too! @MassDCR @EEASecretary @MassGovernor @StreetsBoston @WalkMass @bostonbikeunion @charlesriver @cambbikesafety
Chris Cassa retweeted
Our World Day of Remembrance for Road Traffic Victims group ride and rally brought together hundreds of people on Sunday to remember those we have lost and to encourage our state legislators to make our streets safer. 🧵:
Chris Cassa retweeted
This year for Halloween, I am MASSIVE ADDITIONAL FUNDING FOR THE MBTA. As your State Rep., I have consistently fought to tax the rich and large corporations so we can fund bigger investments in public transit. This work is starting to pay off — and there’s lots more to do! 🚊💰
Chris Cassa retweeted
100% true story: when I was in pre-school, there was exactly one of my close friends that my parents wouldn’t let me go play to their house (because my folks didn’t trust their parenting). And it turns out the mom of this friend was…Jill Stein.
Chris Cassa retweeted
Thank you Boston Mayor Wu for creating a connected protected bike network for everyone of all ages and abilities. @MayorWu @jfh @BostonPWD
With over 1200 crashes, 446 injuries, and 4 fatal crashes, we need action now on all of Memorial Drive. @MassDCR @MassGovernor we need your help to redesign this dangerous highway into a safe and equitable Cambridge Esplanade.

























