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Was chatting with @josephch yesterday and he asked a great, but dreaded, question: how will the eth1 chain, all the existing eth1 contracts, and users fit into the eth2 roadmap (Serenity) long-term, as focus shifts to the eth2 launch?
Casey Detrio retweeted
Yet another major blow to the hypothesis that a microbiome of cancer exists. TLDR: the main results from a 2020 @ScienceMagazine paper claiming to find bacteria in breast cancer simply doesn't hold up. Well done @NFdeMiranda, Jacques Neefjes, et al
🔬In a bid to replicate a prior study, we couldn't confirm LPS presence within breast cancer cells. We did spot it around ducts & in macrophages, aligning with its biology.
#ResearchReplication #Cancer #Microbiome
biorxiv.org/content/10.1101/…
2 years ago: "substantial progress [...] Great! Does this mean the problem is solved, or nearly so? The answer, right now, is no." ...
CASP14 #s just came out and they’re astounding—DeepMind looks to have solved protein structure prediction. Median GDT_TS went from 68.5 (CASP13) to 92.4!!!! Cf. their 2nd best CASP13 struct scored 92.8 (out of 100). Median RMSD is 2.1Å. I think it's over predictioncenter.org/casp14/…
[2 years ago, paraphrasing]: "Perhaps in four years, if we assume that the trendline continues, and we have no real reason to believe that it will, at least not without new conceptual breakthroughs."
Today: "Pretty much solved." "I think it's over."
moalquraishi.wordpress.com/2…
Casey Detrio retweeted
Nature's write-up: nature.com/articles/d41586-0…
Casey Detrio retweeted
The America we want:
Flint sheriff took his riot gear off and marched with protesters instead. xitter.cf/AntWuzHere/status/1266…
I love reading these Bellingcat reports, such page-turners. This latest one is kinda funny, exposing a covert assassin who is (or was) hilariously bad at his job.
Fact Check: A Killing in Berlin, And Putin’s Misleading Claims About A “Blood-Thirsty” Chechen polygraph.info/a/fact-check-…
"The cyclist, [...] after a short chase and an initial misfire, was able to fire five bullets into the victim, with one shot in the chest and another in the head, both at close range."
In Berlin he was seen doing the shooting and ditching his wig. In Moscow his target preempted him, his gun misfired, and it was all recorded on video by a parking lot camera. A state-sponsored covert assassin, you can't make this stuff up lol.
bellingcat.com/news/uk-and-e…
"we’ve [...] found a natural resolution of the equity premium puzzle or — as Ken Arrow used to call it — the volatility puzzle. [...] This relationship holds not only for the stock market indexes we have checked but even for bitcoin."
pump eet.
The ergodicity problem in economics | @ole_b_peters argues that by carefully addressing the question of ergodicity, many puzzles besetting the current economic formalism are resolved in a natural and empirically testable way
go.nature.com/35ZkTSb
I also teared up, was running errands and heard this segment on the radio. Story has been developing and climaxed today in joyous celebration at a cystic fibrosis conf in Nashville. Will treat 90% of CF sufferers (technically not a "cure" but sounds like to a layman).
My childhood neighbor has cystic fibrosis. Was moved to tears listening to this @NPR story about a new highly successful treatment. “Patients who never planned to go to college are now being told to save for retirement” n.pr/2C2fWLs
Amazing work by Jordi on websnark! It's hand-written wasm to do elliptic curves, pairings, etc. We've been benchmarking it, big speedup over alternatives. Excited to use it in some prototype Eth2 execution scripts.
I just released a new version of #websnark. It includes:
1. MNT6753-BoweGabizon-Verifier (recursive snarks used in @CodaProtocol ).
2. BN128-Groth16 verifier.
Verification time: few ms in the browser.
#ethereum. @cdetrio @ebfull @barrywhitehat github.com/iden3/websnark
Casey Detrio retweeted
I just released a new version of #websnark. It includes:
1. MNT6753-BoweGabizon-Verifier (recursive snarks used in @CodaProtocol ).
2. BN128-Groth16 verifier.
Verification time: few ms in the browser.
#ethereum. @cdetrio @ebfull @barrywhitehat github.com/iden3/websnark
Casey Detrio retweeted
Here's my latest @ConsenSys blog post: "#Ethereum 2.0’s Latest Strides Forward" 🚀
No What's New in Eth2 this week - this will have to do😀
medium.com/p/ethereum-2-0s-l…
Casey Detrio retweeted
"Ewasm" slides from Scaling Ethereum by @cdetrio and me: drive.google.com/file/d/1u7L…