🎉 New Impact Factor 7.6 📈 +46% growth in one year 🏅 Top 15% in Oncology At Cancer Drug Resistance, we focus on a single challenge: Understanding why cancer therapies fail—and how resistance can be overcome. Thank you to our global community! oaepublish.com/news/cdr.1547

At #ESMO26 in Madrid? 🇪🇸 Meet the Cancer Drug Resistance team at Hall 8, Booth P8092! Let’s connect, exchange ideas & explore research collaborations. Scan our QR code to join the CDR Scientific Research Network! #Oncology #CancerResearch

Does #lipidremodeling rigidify cancer cell membranes to drive #resistance? New Original article reveals a different story in #melanoma under #dabrafenib: #DTPs accumulate SM & cholesterol without changing membrane fluidity/tension READ HERE: oaepublish.com/articles/cdr.…

How can we bridge the gap between pharma data and academic research to solve cancer drug resistance? Special interview with Prof. Martine Piccart(Université Libre de Bruxelles,@JulesBordet ) Wtach here: oaepublish.com/interviews/cd… #Oncology #BreastCancer #ADCs #HER2

How does deubiquitination fuel cancer drug resistance? A new review in explores #PSMD14 (#RPN11) as a key translational target: Crucial #DUB in 26S #proteasome Drives resistance to #chemo & #targeted #TKIs oaepublish.com/articles/cdr.… #Oncology #DrugResistance #

Why is #pharmacogenomics implementation still lagging behind the science? Interview with Prof. Mary Relling (St.Jude Children's Research Hospital)reveals something important. oaepublish.com/interviews/cd… #Oncology #PrecisionMedicine #PediatricCancer #CancerResearch

How do we overcome 3rd-gen #EGFR #TKI #resistance in #NSCLC? 🫁 A landmark review in by Wolfram Dempke, Klaus Fenchel，Martin Reck et al. maps out what's next: On-target C797S mutations lose covalent TKI binding READ MORE: oaepublish.com/articles/cdr.… #LungCancer #EGFR #Oncology

How do cancer stem cells drive #paclitaxel resistance in #NSCLC? A new study unveils the #ST6GAL1-EGFR-mTOR-SOX2/BMI1 axis: α2,6-sialylation activates #EGFR-#mTOR signaling. READ MORE FINDINGS HERE: oaepublish.com/articles/cdr.… #LungCancer #NSCLC #Oncology #Glycobiology

#FDA approved the 1st targeted therapy for metastatic #PDAC! But acquired resistance looms. In new Review, Dr. Marco Pagano Mariano,Dr Enrica Sgarilliet al. unpack #KRAS inhibitor resistance in #pancreaticcancer READ HERE: oaepublish.com/articles/cdr.… #Oncology #DrugResistance

MelisPoyraz, CyrilCorbet et al. expose the non-genetic metabolic drivers of #chemoresistance in #luminalbreastcancer. Key Findings: Resistant cells enter a low-bioenergetic, metabolic state oaepublish.com/articles/cdr.… #BreastCancer #Oncology #rDrugResistance

NEW REVIEW OUT! Dr. Hsin-An Chen et al. (@TMU_Taipei) examine Adenylosuccinate Lyase (ADSL) in pancreatic cancer chemoresistance Key Insights: ADSL fuels de novo purine synthesis & buffers DNA replication stress oaepublish.com/articles/cdr.… #PancreaticCancer #PDAC #Oncology

Interview with #Thoracic pathologist Prof. Paul Hofman（@IHURespirERA) shares future of liquid biopsy！ As Guest Editor, he invites submissions on: Novel #resistance #biomarkers & #MRD #Plasmaproteomics & #methylation Special Topic Information: oaepublish.com/specials/cdr.…

Interview with Prof. Paul Hofman (IHU RespirERA) breaks down the power of #liquidbiopsy in #thoraciconcology. Key Insights: Why repeat tissue biopsies fail & liquid biopsy bridges the gap . Watch the interview now! oaepublish.com/interviews/cd… #LungCancer #DrugResistance #Oncology

Interview with Prof. @teamoncology Naoto T. Ueno (@UHCancerCenter) outlines next-gen strategies to master ADC resistance. Key Insights: Overcoming TME barriers & tumor emboli penetration #BreastCancer #ADC #DrugResistance #Oncology #PrecisionMedicine #CancerResearch

Join the international Early-Career Editorial Board at Cancer Drug Resistance IF 7.6 (Q1) | CiteScore 10.3 We welcome strong academic background and expertise in the areas relevant to cancer drug resistance. APPLY NOW: docs.google.com/forms/d/e/1F… #Oncology #DrugResistance

Discover how mitochondrial LINC01133 drives cisplatin resistance in lung adenocarcinoma Key Findings: LINC01133 is highly enriched in mitochondria of resistant LUAD cells READ HERE: oaepublish.com/articles/cdr.… #LungCancer #LUAD #DrugResistance #Pyroptosis #PrecisionMedicine

Interview with @teamoncology Prof. Naoto T. Ueno unpacks ADC resistance mechanisms in TNBC & IBC . Key Takeaways: How tumor heterogeneity & emboli drive initial ADC escape in IBC/TNBC oaepublish.com/interviews/cd… #IBC #ADC #DrugResistance #TNBC #Oncology #PrecisionMedicine

How TET2 downregulation limits high-dose ascorbate cytotoxicity in dabrafenib-resistant melanoma.? Key Findings: TET2 & 5hmC are downregulated in BRAFi-resistant melanoma Read full paper here: oaepublish.com/articles/cdr.… #Melanoma #DrugResistance #PrecisionMedicine #Oncology

Dissecting the role of Tertiary Lymphoid Structures (#TLS) in #ColorectalCancer drug resistance. How TLS maturity & HEVs drive in situ anti-tumor immunity ？ Read full paper here: oaepublish.com/articles/cdr.… #TLS #ImmunoOncology #TME #Oncology #PrecisionMedicine #CancerResearch