PostDoc at Meissner Lab @MPI_MolGen - reprogramming the cancer epigenome; PhD @DiefenbacherL @Uni_WUE
Joined January 2019
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🥳I am beyond to finally share the story of my PhD out now: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer nature.com/articles/s41388-0… Lets have a little look what we found: 🧵1/11
Michaela Reissland retweeted
Excited to share our latest research published in @ScienceMagazine! Cryptic splicing can lead to proteotoxic stress, but how do cells cope? Our study uncovers the role of ubiquitination and ER-phagy in mitigating the effects of misfolded proteins. science.org/doi/10.1126/scie…
Special thanks to
@JeroenBugter and @MadelonMaurice
@sinah_loebbert and @Daniel_Solvie
@CristianPG_mlg and the @DikicLab
@SchulteClemens and @maric_hans
@_WolfLab, Peter Gallant and @amir_orian and many many others! 10/11
And last but not least – the biggest shout out to my PhD supervisor and mentor Markus and the whole @DiefenbacherL! None of this would have been possible without your help and support! 11/11
Michaela Reissland retweeted
🚨 Check our latest paper in Oncogen! By combining #proteomics, #spatialtranscriptomics #AlphaFold #organoids and innovative in vivo CRISPR-induced intestinal tumor models, we identified USP10 as a new vulnerability colorectal tumors. Check it out here: rdcu.be/dYz2U
Michaela Reissland retweeted
USP10 emerges as a unique therapeutic target in APC-truncated #ColorectalCancer
🔬nature.com/articles/s41388-0…
@DiefenbacherL
#OpenAccess
Michaela Reissland retweeted
We congratulate Michaela Reissland and the whole team in Markus Diefenbacher's lab on their new paper in Oncogene. In the study, they were able to demonstrate the role of USP10 in Wnt signalling in colorectal cancer models. Thank you for the opportunity to contribute.
USP10 emerges as a unique therapeutic target in APC-truncated #ColorectalCancer
🔬nature.com/articles/s41388-0…
@DiefenbacherL
#OpenAccess
So proud of my first first-author paper🥳Can´t be more grateful to all who contributed wrapping up my PhD project to this great story! Little thread about our most important finding will follow soon🧵
USP10 emerges as a unique therapeutic target in APC-truncated #ColorectalCancer
🔬nature.com/articles/s41388-0…
@DiefenbacherL
#OpenAccess
Michaela Reissland retweeted
Our PhD program is now open to applications for 2025 admissions. Too much cool science to summarize, take a look and apply! Deadline Jan 7th.
Call open: We are looking for motivated #PhD students who want to work at the interface between molecular life sciences and computational sciences. #IMPRS #IMPRSBAC @maxplanckpress @FU_Berlin @DRS_FU
Check out our projects and apply until Jan 7th, 2025! molgen.mpg.de/IMPRS/applicat…
👋#science twitter - help needed! We are desperately looking for commercially available CRC-patient organoid lines and normal colon organoids. Any recommendations other than Atcc or Sigma? #organoids #CancerResearch
Neither @ATCC_LGC nor @SigmaAldrich were able to deliver the ones, we´ve ordered so far to germany (just needed >4 month to figure that out..🙄)