Comprehensive Resistance Prediction for Tuberculosis: an international Consortium

Joined March 2017
Don't forget about the new and exciting post going within MMM for a front-end web-developer! my.corehr.com/pls/uoxrecruit…
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🚨Last few days to apply to be our Programme Manager to help us research infectious diseases. Deadline is noon Mon 7 Nov. bit.ly/3SUgKYT
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Want to help drive forward a diverse range of research projects in clinical microbiology, including pathogen genomics, epidemiological studies and rapid diagnostics? Join us as our Programme Manager! Deadline noon 7 Nov 2022 bit.ly/3SUgKYT @NDMOxford @OxfordBRC
Study by @crypticproject presents an #OpenSource dataset of 12,289 #Mycobacterium #tuberculosis clinical isolates from 23 countries on 5 continents, including genomic sequence & susceptibility profile for 13 drugs of each isolate #TB #PLOSBiology plos.io/3bZBn5K
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Phenotyping & sequencing 10,000 #Mycobacterium #tuberculosis genomes identifies previously uncatalogued genetic variants associated with resistance to 13 new & repurposed 2nd line & 1st line drugs #TB #AntiMicrobialResistance @crypticproject #PLOSBiology plos.io/3bUiOjj
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Replying to @AliceBrankin
@AliceBrankin talking about fluoroquinolones in Hall K at 0854. Part of a Cutting Edge in Mycobacterial Research session at #ECCMID @ModMedMicro @crypticproject
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Check out ‘Under the Mask’, a film about people on the Thai-Myanmar border with #tuberculosis. Directed by Saw Ler Wah and supported by @wellcometrust, MORU, SMRU and FilmAid. bit.ly/3w5xSQF
My group has focussed on the genome analysis for CRyPTIC, and we are very happy to present this study on a new methodology developed by @martibartfast, with an application to the rifampicin resistance : doi.org/10.1101/2021.09.15.4… A thread (figure to tempt you - see below) 1/18
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Really pleased to have got the first preprint from the @BashTheBug @the_zooniverse project up! Here: bit.ly/btb_paper @crypticproject @ModMedMicro
BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular ... biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Epidemiological cutoff values for a 96-well broth microdilution plate for high throughput research antibiotic susceptibility testing of M. tuberculosis medrxiv.org/cgi/content/shor… #medRxiv
Current exhibition @kunstpalais upcoming @museumboerhaave @cafaartinfo #Beijing @KunsthalleTue temporarily closed @NationalCraft @edenproject + info on projects @vertigo_starts @ICY15_Vienna @crypticproject @ARTDATAHEALTH1 @HCAILeeds @H2020_CHIC & more annadumitriu.co.uk/news/ – at Brighton, England
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Evaluation of antibody testing for SARS-Cov-2 using ELISA and lateral flow immunoassays medrxiv.org/content/10.1101/…
This is how your work on classifications has helped us fight antibiotic resistance and Tuberculosis! bit.ly/3ae9XT6 @ModMedMicro @crypticproject @NDMOxford @OxfordBRC @the_zooniverse
Powerful antibiotic discovered using machine learning for first time theguardian.com/society/2020… Interesting piece on Machine Learning and antibiotics
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We hope that this @wellcometrust @acmedsci funded project will be one of many in which @nanopore sequencing can make a difference in the fight against TB @StopTB xitter.cf/nanopore/status/983305…
For the next two weeks, we are working with the Institute Pasteur @pasteurMG to train scientists in Madagascar to ID/characterise TB and its drug resistance profile using @nanopore. In week 2 the teams will head out of the city (more challenging resources). #nanoporemadagascar
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Validation of a 14-drug microtitre plate that includes delamanid and bedaquiline for susceptibility testing of M. tuberculosis biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Automatically detecting growth of #tuberculosis using a python module: post bit.ly/2B1RFG4 and preprint doi.org/10.1101/229427
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Fast automated detection of bacterial growth on 96 well plates doi.org/10.1101/229427 @crypticproject @ModMedMicro @OxfordBRC
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