@dahilger

Opinions my own.

 Philipps-University of Marburg
Joined February 2017
  • Tweets473
  • Following271
  • Followers311
3Media
Daniel Hilger retweeted
NatureStructMolBiol@NatureSMBOct 13
New online! μ-Opioid ligands tune G-protein opening kinetics dlvr.​it/TVvD52
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Daniel Hilger retweeted
NatureStructMolBiol@NatureSMBOct 13
New online! Ligand-dependent G protein dynamics underlying opioid efficacy dlvr.​it/TVvCzk
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New review article in @NatRevDrugDisc on Functional Dynamics of GPCRs, based on discussions from a great CECAM GPCR meeting. Congrats to Vittorio, Paolo, and all the other coauthors! #NMR #NMRchat nature.com/articles/s41573-0…
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We are recruiting a young researcher to join our dynamic lab at UCSF - this is a great opportunity if you would like to get some research experience before graduate or medical school! aprecruit.ucsf.edu/JPF05305. Please RT!
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Replying to @MiriamStoeber
Congrats Miriam and all the authors! Beautiful study and exciting findings.
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When you get an Aston Martin in return for a favor, you know you have great colleagues !!!🤩
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Are you interested in #GPCR / #Gprotein signaling and #biosensor development? Then please apply for this open #PostDoc position in my new Emmy Noether Research Group @Uni_MR! stellenangebote.uni-marburg.… #newPI
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An announcement: The O'Brien lab is hiring!! If you're interested in GPCR structural biology, dynamics, and/or drug discovery, see posting for postdoc position(s) here (apply.interfolio.com/153041) and (NEW!) lab website (evanobrienlab.com) for more. Please share this widely!!
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Please reach out if this is of interest and stay tuned for more!
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📢I have open PhD student and Postdoc positions to join my #EmmyNoether lab to decipher how #GPCR-specific signaling is achieved by heterotrimeric #Gproteins! ‼️Interested in developing novel biosensors💡 that reveal yet invisible states and processes🔍? ➡️DM or email me📨‼️
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Daniel Hilger retweeted
Mick lab@MickLab15 Jul 2024
Please RT: Our department @Saar_uni is looking for a new group leader in #biochemistry, #membrane, #organelle #biology. Great opportunity for early career young scientists in a young, vibrant and supportive environment. Send applications until 11.Aug 2024. uni-saarland.de/fileadmin/up…
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Daniel Hilger retweeted
John Janetzko@jjanetzko9 Jul 2024
My lab has multiple openings for those interested in doing some very cool science in beautiful Colorado! Research assistants (tech/lab manager level): cu.taleo.net/careersection/2… Postdoctoral fellows: cu.taleo.net/careersection/2… DM or email me if interested and 🙏 share broadly 🪃
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Excited to share our recent work on the discovery, characterization, & implementation of a new opioid receptor negative allosteric modulator, out in @Nature today! nature.com/articles/s41586-0…

A µ-opioid receptor modulator that works cooperatively with naloxone

Nature - A newly discovered negative allosteric modulator of the µ-opioid receptor works together with naloxone to potently block opioid agonist signalling with reduced adverse effects.

nature.com
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If you have a background in chemistry, biophysics, cell biology and ambitious for research we are searching for you!! Apply to do your PhD with us! jobs-sf.ukmuenster.de/job/UK…
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Replying to @HSchihada @Uni_MR
We will dive into the fascinating question how so many #GPCRs expressed in the same cell can activate the same #Gprotein but induce distinct signals and cellular responses! Interested? Please reach out ✉️ uni-marburg.de/en/prfolder-e…

How molecular specificity emerges

More than "on" and "off": German Research Foundation funds new Emmy Noether Group at Philipps-Universität

uni-marburg.de
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Daniel Hilger retweeted
Daniel Wacker@WackerLab8 May 2024
Lessons from a Toad Psychedelic about the Role of different Serotonin Receptors in Psychedelic Physiology: nature.com/articles/s41586-0… Congrats to Audrey and @LankriDavidIL in this collab with @SamesLab and @ScottRusso published in @Nature
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Molecular basis of proton-sensing by G protein-coupled receptors biorxiv.org/content/10.1101/… 9500 mutations !!!!🤯

Molecular basis of proton-sensing by G protein-coupled receptors

Three proton-sensing G protein-coupled receptors (GPCRs), GPR4, GPR65, and GPR68, respond to changes in extracellular pH to regulate diverse physiology and are implicated in a wide range of diseases....

biorxiv.org
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Profiling the proximal proteome of the mu opioid receptor identifies novel regulators of receptor signaling and trafficking biorxiv.org/content/10.1101/…

Profiling the proximal proteome of the mu opioid receptor identifies novel regulators of receptor...

The mu opioid receptor (μOR), a prototypic member of the large G protein-coupled receptor (GPCR) family, represents an important target of therapeutic and abused drugs. To date, most of our underst...

biorxiv.org
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Molecular insights into G protein specificity and biased agonism at the β2-adrenergic receptor | bioRxiv biorxiv.org/content/10.1101/…
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