@david_soave
Joined May 2016
  • Tweets13
  • Following47
  • Followers44
“Our results may be informative to many patients with cancer who believe their diagnosis is attributed to previous anxiety or depression,” said Laurier's @david_soave, who co-led this international study.
Ontario Institute for Cancer Research (OICR)@OICR_news5 Dec 2023
Do #anxiety and #depression affect our risk of cancer? An international research project used @ON_HealthStudy data to investigate possible links between depression, anxiety and certain cancers. oicr.on.ca/do-anxiety-and-de… #mentalhealth
1
2
261
A recent @NatureComms paper by @inofechm, Dr. @david_soave, Dr. Philip Awadalla (@AwadallaLab) and Dr. Sagi Abelson has been selected as an Editors' Highlight. 👏 nature.com/articles/s41467-0…

Pan-cancer classification of single cells in the tumour microenvironment

Nature Communications - The accuracy and granularity of classifying cell types in the tumour microenvironment (TME) from single-cell RNA-seq data is impacted by heterogeneity among cancer cells and...

nature.com
3
6
540
How do things like age, ancestry & environment alter our gene expression? This is a question Michelle Harwood (@mp_harwood) focuses on in her research. In this Q&A, we talked molecular genetics, research & impostor syndrome. ➡️ bit.ly/3ndY2jX
5
4
1,688
How to identify cells from within heterogenous tumour? PhD candidate @inofechm has developed scATOMIC that uses single-cell RNAseq to analyse multicellular cancer tumour microenvironment! Beautiful work! @AwadallaLab @OICR_news nature.com/articles/s41467-0…

Pan-cancer classification of single cells in the tumour microenvironment

Nature Communications - The accuracy and granularity of classifying cell types in the tumour microenvironment (TME) from single-cell RNA-seq data is impacted by heterogeneity among cancer cells and...

nature.com
2
8
399
David Soave retweeted
GenomeWeb@GenomeWeb28 Oct 2022
Cell-free DNA Methylome Signatures Show Potential for Early Cancer Detection. In a study presented at the ASHG annual meeting this week, researchers identified plasma cfDNA methylation profiles that were predictive of certain cancers. ow.ly/SOYX104akHu
3
2
9
Very happy to share our new publication in @ScienceAdvances! We show that selection affects allelic expression in humans through recombination and effective population size. Huge thanks to my team of past and present members of the @AwadallaLab. bit.ly/abl3819

Recombination affects allele-specific expression of deleterious variants in human populations

Recombination, population size, and environment contribute to altered allelic expression of damaging mutations.

science.org
3
9
1
23
RT! 2021 Distinguished Lecture Series in #Statistical Sciences delivered by @KerrieMengersen Professor Statistics @QUT; Deputy Director @ACEMathStats. Sep 20 & 21, 2021 | 4-5 pm ET | Register bit.ly/3k72bSN #DataScience @LaurierMath @QUartsci @BrockUFMS @UTM_MCS
11
22
Out today in @NatureComm @kimskead used advanced evolutionary models to study why only some people with #ARCH develop #AML: mildly damaging mutations may protect you from developing cancer! Joint w @awadallalab @OICR_news @uoftmedicine @sloan_kettering 🧵nature.com/articles/s41467-0…
2
26
6
98
Our new preprint with ⁦@KimSkead ⁦@AwadallaLab⁩ and⁩ ⁦@quaidmorris⁩ on how Interacting evolutionary pressures drive health outcomes in aging blood is up on biorxiv. Feedback welcome! biorxiv.org/content/10.1101/…

Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood

A small population of self-renewing, hematopoietic stem cells continuously reconstitutes our immune system. As we age, these cells, or their pluripotent descendants, accumulate somatic mutations;...

biorxiv.org
2
8
1
21
Blood samples, #biostatistics and a fresh perspective: The makings of a cancer prediction machine: ow.ly/uvuB50v9ioI @UWaterloo @cptproject @Laurier #cancerresearch #DNA #machinelearning #ctDNA #liquidbiopsies
3
1
7
Load more