From CANCER STATISTICS 2024 #PancreaticCancer remains the third most common cause of cancer related mortality amongst men and women combined. While 5y survival for localized cancer has steadily increased (left), the overall survival rates continue to be mostly driven by the majority of patients presenting with advanced stage surgically unresectable disease (right), underscoring the pivotal importance of earlier diagnosis. I am hopeful that the advent of better therapeutics (including newly developed KRAS targeted agents used in combination) will start having an impact on survival in later stages of disease as well. Obviously miles to go. acsjournals.onlinelibrary.wi… @NCIprevention @letswinpc @PanCAN @lustgartenfdn @AmericanCancer @OncoAlert