bioinformatics phd student at harvard interested in statistical genetics and genomics
Joined July 2018
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excited to share our new preprint looking at mosaic chromosomal alterations in blood whole genome sequencing data! i learned tons working on this project, and i hope our findings are of interest to those thinking about CH, somatic mosaicism, and genetics.
medrxiv.org/content/10.1101/…
David Tang retweeted
Very excited to share our preprint demonstrating that common genetic variants contribute to variable expressivity in rare telomere biology disorders! Highlights below 1/
medrxiv.org/content/10.1101/…
David Tang retweeted
Our new work uses GxDrug interaction to model genetic effects on drug response in cross sectional data. Includes a new method for GxE TWAS. There are important caveats, but we hope this is a step toward more precise treatments
New preprint. In this paper we quantify heritability of drug response and identify involved genes by applying gene-environment interaction methods to biobank data. medrxiv.org/cgi/content/shor…
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David Tang retweeted
Our language decoding paper (@AmandaLeBel3 @shaileeejain @alex_ander) is out! We found that it is possible to use functional MRI scans to predict the words that a user was hearing or imagining when the scans were collected nature.com/articles/s41593-0…
super excited to share our new paper on polygenic epistasis! we introduce a new model and show how structured statistical epistasis can help us study complex trait biology. huge thanks to my friend and lab-mate @studyjeromics, and my mentor @andywdahl!
biorxiv.org/content/10.1101/…
