Dr. Pierre Thibeault (@frenchnerd) profile picture

Postdoctoral fellow at University of Toronto. Molecular pharmacologist - love all things GPCR. All opinions are my own. 🏳️‍🌈 he/him

Toronto, Ontario
Joined April 2012
Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)Photo by Dr. Pierre Thibeault (@frenchnerd)
Dr. Pierre Thibeault retweeted
One force field for proteins, DNA, lipids and carbohydrates? Introducing SO3LR Tauri, a pretrained ML force field that couples a fast neural network with explicit repulsion, electrostatics and dispersion. It takes a step toward a unified model that describes all major classes of (bio)molecules at quantum-mechanical accuracy. arxiv.org/abs/2611.06237 1/12🧵
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Seeing “hey grok” followed by a question that could easily be reasoned with common sense - so often, has made this app almost unusable for me. It’s like constant rage bait. “Hey grok what happens if I flood my house?” “Your house would be flooded” wowwww the wonders of AI 🫩
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Dr. Pierre Thibeault retweeted
現役の研究者はAIを使って研究していて自分がバカになっていく感覚を味わっていると思うけど、AIネイティブの若者が研究に入ってこのAI以前に比べて「バカになる」感覚を感じずに研究をしていくとき、研究がどうなっていくのか気になる
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Dr. Pierre Thibeault retweeted
Sam Altman: AI has fully defeated most of the ways people authenticate today. “Voiceprints as authentication are a crazy thing to still be doing. AI has fully defeated that.” “I am very nervous that we have a significant impending fraud crisis.” “Just because we’re not releasing the technology doesn’t mean it doesn’t exist.” “Soon, a video FaceTime will be indistinguishable from reality.” “People are going to have to change the way they verify who they’re actually talking to.”
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Dr. Pierre Thibeault retweeted
.@maggie_utgaard, @myosincity, @pwoakes et al. show that #septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the #nucleus. hubs.la/Q04C2s5L0 #Cytoskeleton #Mechanobiology
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I feel like I'm going insane. If this is true he should go to prison immediately, but for some reason everyone just lets him keep on fucking around?
OpenAI CEO Sam Altman: "I don't even know a dramatic enough word to use… models can find bugs that are outside of the normal threat model of what we think a hacker can do… hardware-level, insane stuff… I no longer think we're gonna be able to just patch all the bugs." It's over.
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Based on how they’re doing in the polls - right ship, wrong metaphor.
The Titanic, famously the ship that turned around
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We have to stop pretending like this is inevitable and normal. Using AI everyday is not the solution for graduate students - not when it gets them to the point where they are no longer working the problems. I know that’s not every student but I am seeing this constantly where
Un investigador de Anthropic acaba de decirle a una sala llena de doctorandos que su plan de carrera ya no existe. La charla se titula "El fin del Antropoceno" y los datos son brutales: → El cómputo para entrenar modelos se multiplicó por 10 millones en la última década → La duración de las tareas que una IA completa sola se duplica cada pocos meses → Desde hace 7 meses los modelos resuelven problemas abiertos de Erdős que los matemáticos no habían logrado cerrar → En San Francisco, tener "timelines largos" significa pensar que la AGI llega en 10 años Su proyección: el cómputo de 2030 será 10.000 veces mayor que el de 2025. Todavía estamos al principio de la exponencial. Sus 3 consejos para los estudiantes: 1. Usa la IA cada día. Si estás sobre la exponencial, nunca te quedas atrás de ella. 2. Elige proyectos que mejoren cuando el cómputo escala. El resto quedará resuelto antes de que los termines. 3. Deja de planificar tu carrera como si fuera estable. La opción segura ya no compra seguridad, ya no existe. Y una frase que resume todo: "Escribir es pensar. Si externalizas tu escritura, externalizas tu pensamiento." La charla completa aquí ⬇️
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agrees and changes course to whatever you tell it is correct.
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And like every other scientist I am of course exploring its positive uses in my research but I still think we are putting the cart way before the horse and maybe even using the cart to cause irreparable harm
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Having a meltdown about not getting the Nobel Peace Prize while in a war you started is wild…
US President Trump has a meltdown after losing the Nobel Peace Prize to Indian-origin South African jurist Navi Pillay
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Dr. Pierre Thibeault retweeted
BREAKING: OpenAI’s solution to Navier–Stokes does not match its Lean verification. The most important article to read today is not one of OpenAI’s 700 AI-generated math papers. It is this other paper, making a deep and worrying point: A Lean-verified proof does not automatically validate the proof written in natural language, nor does it mean that the formal statement captures the intended theorem. During translation, an AI can change an assumption, weaken a statement, or replace the argument entirely. It can hallucinate another theorem. Lean correctly verifies the result. But the proved result may no longer be what the paper claims. This is a general problem. Things get spicy when the authors examine OpenAI’s proposed Navier–Stokes solution. They identify at least two mismatches between the written intermediate results and their Lean counterparts: One estimate claims that four additional input derivatives suffice. The Lean version requires five: a weaker result. A pressure-flux estimate is obtained through a different bound, and proved through a different argument. It is not clear whether these mismatches invalidate the entire proof. But they raise an important issue. OpenAI is flooding us with claimed revolutionary breakthroughs. Yet nobody knows whether the proofs are correct or whether they prove what they claim to be proving. Epistemia at scale. * Paper in the first reply
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I’m at a cineplex and I’ve seen three trailer ads fundraising for various hospitals in Toronto. It’s almost as if @fordnation should stop cutting healthcare funding…
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Dr. Pierre Thibeault retweeted
White House Accord on Super Intelligence
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Dr. Pierre Thibeault retweeted
Just the Editor-in-Chief of Nature advising scientists not to share their data and findings with external AI model companies.
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Dr. Pierre Thibeault retweeted
Amazing early clinical trials results based on groundbreaking studies from @StephAngers and colleagues. A tangible example of how funding in basic science translates into new treatments for patients. @CIHR_IRSC @uoftmedicine @DonnellyCentre Congratulations to all involved.
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