Twitter Page for The Getz Lab @MGHCancerCenter and @broadinstitute | Computational genomics of #cancergenes
Cambridge, MA
Joined April 2019
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Gad Getz Laboratory retweeted
⭐️Now online
In a large cohort of patients with ICB-treated glioblastoma, Catherine J. Wu & colleagues show that baseline mesenchymal transcriptional state predicts therapy response, and transition to non-mesenchymal state results in acquired resistance.
nature.com/articles/s43018-0…
Gad Getz Laboratory retweeted
Excited to share some of my PhD work out today in @NatureCancer! Integrating bulk and single-nucleus genomic approaches, we identify distinct determinants of survival and acquired resistance to ICB versus standard chemoradiation in glioblastoma. nature.com/articles/s43018-0…
RT @JonRoseAI: 🚨 New paper out in Nature Communications! 🧬
We identified (as well as where and when) genetics affects epigenetics,
This one…
Gad Getz Laboratory retweeted
In a new study, researchers from @MGHCancerCenter @broadinstitute and colleagues investigated why breast #cancer therapy tamoxifen may lead to higher risk of uterine cancer.
Read more: massgeneralbrigham.org/en/ab… nature.com/articles/s41588-0… @getz_lab
Gad Getz Laboratory retweeted
On #WorldLungCancerDay, we focus on BSF-supported U.S.–Israel research tackling one of cancer’s toughest challenges: persister cells.
Dr. Yaara Oren @TelAvivUni & Dr. Gad Getz @broadinstitute are uncovering how these elusive cells survive therapy - and how we might stop them.
Gad Getz Laboratory retweeted
1/ 🧵Check out our new study in @NatureGenet, which examines how precancerous conditions (MGUS/SMM) evolve into Multiple Myeloma, and offers new computational methods to predict progression risk and model cancer evolution.
doi.org/10.1038/s41588-025-0…
Gad Getz Laboratory retweeted
In a new study, researchers from @MGHCancerCenter and colleagues' 'cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer. The study was published in @CD_AACR.
Read more: massgeneralbrigham.org/en/ab… @getz_lab @DrFranVazquez
doi.org/10.1158/2159-8290.CD…
Gad Getz Laboratory retweeted
Now online in @CD_AACR: Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets - by @Vindhya_Vijay, Negin Karisani,@getz_lab, Nabeel Bardeesy, and colleagues doi.org/10.1158/2159-8290.CD… @MGHCancerCenter @broadinstitute
Excited to share our comprehensive cell line atlas for biliary tract cancer (BTC) in collab with Dr. Nabeel Bardeesy @MGHCancerCenter & @DrFranVazquez, and led by @Vindhya_Vijay & Negin Karisani! doi.org/10.1158/2159-8290.CD… @CancerDepMap @CD_AACR
Also see: massgeneralbrigham.org/en/ab…
Gad Getz Laboratory retweeted
Our paper on establishing targeted therapy for MM with 1q+ is online ahead of print in @BloodJournal! w/ Liz Lightbody, Mairead Reidy, @IrenemGhobrial @gaddyg & Salomon Manier! ashpublications.org/blood/ar…
Gad Getz Laboratory retweeted
ABSTRACT SELECT: @TimCoorens from @getz_lab
@broadinstitute details novel technologies to detect somatic mutations across normal tissues at the 2025 @AGBT General Meeting. #AGBTGM
Gad Getz Laboratory retweeted
Let's walk through what we found in our new study using single-cell RNA-seq on tumor and immune cells from pts w/ asymptomatic Waldenstrom's Macroglobulinemia - out now in @NatureComms! W/ @Yoshi_konnykid @IrenemGhobrial @gaddyg #wmsm #mmsm nature.com/articles/s41467-0… 1/
Gad Getz Laboratory retweeted
Check out our new study using single-cell RNA-seq to characterize immune dysregulation and identify molecular subtypes in patients with asymptomatic Waldenstrom’s Macroglobulinemia! #wmsm
W/ @Yoshi_konnykid , @IrenemGhobrial, @getz_lab @WMIWMF
nature.com/articles/s41467-0…
Gad Getz Laboratory retweeted
Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in @Nature! We outline the scope, vision, opportunities and challenges of these projects here:
nature.com/articles/s41586-0…
With @rheinbay_lab and additional Broad collaborators, we are excited to enter into this partnership with @Inocras to analyze whole genomes for the benefit of cancer research and cancer patients 🧬! @GenomeDoctor @BroadInstitute @MGHCancerCenter
Congrats to @gaddyg and the other 5 amazing #broadies for being named today as Core Institute Members @broadinstitute!! 🎉
Six leading scientists and longtime members of the Broad community have been named as new core institute members at Broad: @getz_lab, @AnnaGreka, Nir Hacohen, @macosko, @bmneale, and @pardissabeti Congratulations to all! broad.io/CoreInstituteMember…
ALT A collage of headshots featuring six individuals. The top row shows a man with short gray hair and glasses, a woman with long dark hair, and a man with short dark hair. The bottom row shows a man with curly dark hair and glasses, a man with short brown hair and glasses, and a woman with shoulder-length brown hair wearing a red shirt. The backgrounds vary from indoor settings to outdoor greenery.
Gad Getz Laboratory retweeted
We thank Ofer Shoshani @ShoshaniOfer , Uri Ben-David @BenDavidLab and Yossi Yarden, Cancer Genome Structure & Dynamics meeting (xitter.cf/BenDavidLab/status/181…). It was a great meeting and it was nice to meet Gaddy Getz @gaddyg as well.
Gad Getz Laboratory retweeted
Excited to present at #FOGBoston tomorrow on making @UltimaGenomics turnkey compatible with all existing downstream tools, with a real-world example leveraging methodology developed here in the @getz_lab to infer cancer phylogenies at resolutions not possible without #WGS.
#Sequencing is a pivotal topic at the heart of the Festival of Genomics & Biodata. Join us tomorrow at #FOGBoston for insightful talks and an expert sequencing panel that will delve into this topic. Don’t miss out—register now: hubs.la/Q02Bl-ql0
We’re lucky to have you on our @getz_lab team, @lizd0m!! We are so proud of the breakthroughs you make in the lab AND on the water! 🧬🛶🥇
@broadinstitute #WhyIScience
“As someone who’s been rowing for a pretty long time, I think it’s really important to have a balance between two things that you find value in.” Learn how computational biologist @lizd0m juggles research and life as an elite rower in a #WhyIScience Q&A: broad.io/WISLiz
ALT Liz Martin, woman wearing white visor and navy shirt, rowing on river