@hankadel

PD fellow in Fisher lab at MGH. interested in pigmentation, LROs, and cool animals. tweets by me signed -h

 Cambridge, MA
Joined March 2009
  • Tweets714
  • Following741
  • Followers361
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Hank Adelmann retweeted
Corey N Cunningham@CNFXCJul 7
Excited to share our new preprint from @RutterLab, identifying a melanosomal tyrosine transporter! biorxiv.org/content/10.64898…

SLC16A6 is a tyrosine transporter for the melanosome

Cells enable specialized metabolism by compartmentalizing metabolic pathways into distinct organelles, which requires the membrane transport of metabolites. In melanocytes, the amino acid tyrosine is...

biorxiv.org
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Hank Adelmann retweeted
The Antihero@YourBoy_KG21 Oct 2025
Are the developers at Outlook happy with their search function?
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In vivo follow-up on MFSD12 and an embryonic lethal phenotype that we found was recoverable with cysteamine treatment. with @DMSabatini and @FisherLabMGH Out today! pnas.org/doi/10.1073/pnas.24…

Lysosomal reduced thiols are essential for mouse embryonic development | PNAS

While it has been appreciated for decades that lysosomes can import cysteine, its significance for whole-organism physiology has remained uncertain...

pnas.org
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Some final dunks contributed by @avanthikav and a @LironBarPeled squad/stefan harry. Students lingjuan luna huang and michelle liu were also very critical contributors!
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Congratulations Hank Adelmann @hankadel on this beautiful in vivo follow to his discovery of MFSD12 as a lysosomal cysteine transporter. Lysosomal reduced thiols are essential for mouse embryonic development | PNAS pnas.org/doi/10.1073/pnas.24…

Lysosomal reduced thiols are essential for mouse embryonic development | PNAS

While it has been appreciated for decades that lysosomes can import cysteine, its significance for whole-organism physiology has remained uncertain...

pnas.org
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POV: you're a Nevron. I have three Gradient charges. I am in Virtuose stance. Sciel has just used Fortunes Fury.
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A TOUR DE FORK Banger read pnas.org/doi/10.1073/pnas.25…

Mechanism and application of thiol–disulfide redox biosensors with a fluorescence-lifetime readout...

Genetically encoded biosensors with changes in fluorescence lifetime (as opposed to fluorescence intensity) can quantify small molecules in complex...

pnas.org
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Good stuff pnas.org/doi/10.1073/pnas.24…

State-dependent motion of a genetically encoded fluorescent biosensor | PNAS

Genetically encoded biosensors can measure biochemical properties such as small-molecule concentrations with single-cell resolution, even in vivo. ...

pnas.org
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first out of touch thursday of 2025! happy new year columboheads
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We’ve preprinted a small follow-up to our identification of MFSD12 as a mediator of lysosomal cysteine import. Would love to discuss, so please get in contact if you have comments or suggestions! biorxiv.org/content/10.1101/…

Lysosomal reduced thiols are essential for mouse embryonic development

While it has been appreciated for decades that lysosomes can import cysteine, its for organismal physiology is unclear. Recently, the MFSD12 transmembrane protein was shown to be necessary to import...

biorxiv.org
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happy thursday to ya
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Hank Adelmann retweeted
Tenacious D
@tenaciousd29 Feb 2024
STILL BELIEVE 🐼💥🐯 @jackblack @GassLeak
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Blah blah blah
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First date as married guys
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Hank Adelmann retweeted
Gary Busey@THEGaryBusey14 Sep 2023
Hey @Samsung why is my BRAND NEW FRIDGE a lemon? 🍋 🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋🍋😢😢😢😢
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Ayo @DanielRConnolly graduated hbd graduation dad @raviusheth
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👿👿
Fisher Lab@FisherLabMGH21 Apr 2023
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