@hariharmm

Postdoc in the Parker lab @CUBoulder @HHMI studying RNA processes in repeat expansion disorders. PhD from @UMich. He/him, views mine, 🇮🇳➡️🇺🇸

 Ann Arbor, MI
scholar.google.com/citations?user=EjYBkNUAAAAJ&hl=en&authuser=1
Joined June 2020
  • Tweets173
  • Following334
  • Followers169
13Media
Harihar Mohan retweeted
ShorterLab@ShorterLab18 Jul 2025
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology | Science Advances science.org/doi/10.1126/scia…

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional...

Virus-like proteins help our cells respond to environmental stress.

science.org
8
36
2,728
Our paper discovering novel roles for the retrovirus-like proteins RTL8 and PEG10 in shaping stress granule biology is now online on Science Advances! #llps #stressgranules science.org/doi/full/10.1126…

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional...

Virus-like proteins help our cells respond to environmental stress.

science.org
2
1
6
425
Earlier this month, I defended my PhD in front of friends and family. I’ve dreamed of this moment forever and I’m glad it came true. Thanks to my mentors, Drs. Paulson and Sharkey, and my committee! I will be starting a postdoctoral position in Dr. Roy Parker’s lab at CU Boulder.
2
8
387
How it started vs how it’s going… On Sept. 1, 2017, I started as a new postdoc in @UMCDB and today I’m faculty. I feel truly blessed to have achieved what felt like an impossible goal, but I made it and the @SpriggsLab is officially open! 🥳 Let’s do this! 🦠🔬🧫 #NewPI
56
63
5
948
Excited to share ‘Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins’, by phenomenal superstar postdoc Aakriti Jain @aakritijain24 and amazing collaborators @rushika_perera, Guido Bommer, Charly Craik and @OlzmannLab: science.org/doi/10.1126/scie…

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic...

science.org
37
69
3
248
49,770
We’re excited to announce the release of our latest collection of 4 biomolecules—F-ATPase, RuBisCo, RAG-1/2, and GFP - now available as interactive flip book versions 🥳 📖 These flip books are designed to serve as fun and educational flash cards, perfect for teaching and learning about these essential biomolecules. We’ve also made PDF versions available for download, so you can have them on hand anytime 😍 🤩 We hope you enjoy exploring these resources as much as we enjoyed creating them! Team behind these infographics - @Arushi_Batra28 and @AgastyaSingh 😁 👉 buff.ly/46oaVT6
1
11
4
57
6,921
We are excited to introduce first-of-a-kind immunofluorescent probes to visualize RNA in cells! @NAR_Open Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells academic.oup.com/nar/article…

Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells

Abstract. Although antibody derivatives, such as Fabs and scFvs, have revolutionized the cellular imaging, quantification and tracking of proteins, analogo

academic.oup.com
7
73
4
350
24,484
New preprint! We predict 9,452 human-pathogen protein interactions, tripling structural knowledge for key pathogens. 🔍 Only 0.2% of known interactions have solved structures—structure prediction can bridge this gap for drug & vaccine design. Read more: biorxiv.org/content/10.1101/…
1
34
1
187
10,913
Our preprint uncovering how endogenous retrovirus-like proteins reshape fundamental stress granule features is now online! So many awesome discoveries, the coolest being virus-like particles within stress granules! Cryo-CLEM work was led by Martin from @s_mosalaganti lab 1/8
4
9
3
29
12,857
If you’d like to talk to me about this work, I’ll be at #ASCB2024 board B98 this morning!
3
105
Harihar Mohan retweeted
Edward Chuong@edchuong12 Dec 2024
Paper Link: "Regulation of human interferon signaling by transposon exonization" cell.com/cell/fulltext/S0092…

Regulation of human interferon signaling by transposon exonization

Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.

cell.com
1
3
16
2,073
This light-sheet microscopy three-dimensional rendering shows a first-of-its-kind mouse whole-brain mRNA analysis at single-cell resolution. Learn more in this week’s issue: bit.ly/3CCapy5
15
163
24
599
343,960
Just created a new BlueSky account - @harimohan.bsky.social. If you’re on there, we should connect!
56
Can we make Acoustic Proteins with different "colors" the way the developers of GFP made BFP, YFP, etc?🌈 Yes, via #directedevolution of #gasvesicles! Congrats to @nivinnystrom et al on the first GVs multiplexed based on nonlinear response to ultrasound. biorxiv.org/content/10.1101/…
7
74
9
437
57,420
retrovirus-like proteins! Huge thanks to all co-authors, including @alexmgreer and @BarmadaLab. Big shoutout to @Castaneda_lab and @smslmoon for their guidance. And lastly to my advisors, Hank Paulson and @LisaSharkey20 for helping me explore these fascinating ideas! 7/8
2
2
423
Read more - biorxiv.org/content/10.1101/……… 8/8 @Pha_Tran_Papers @biorxiv_cellbio @UMichCMB #condensate #ALS

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional...

The human genome is replete with sequences derived from foreign elements including endogenous retrovirus-like proteins of unknown function. Here we show that UBQLN2, a ubiquitin-proteasome shuttle...

biorxiv.org
4
377
Load more