With Immudex' proprietary Dextramer® and dCODE Dextramer® technologies, we develop and market reagents and assay solutions to measure disease-specific immunity.
Copenhagen, Denmark
Joined July 2018
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CAR-T cells come in different flavors 🍦 – here’s how to detect them!
We provide Custom CAR #Dextramer® reagents to match your target antigen.
💌Contact us at 𝐜𝐮𝐬𝐭𝐨𝐦𝐞𝐫@𝐢𝐦𝐦𝐮𝐝𝐞𝐱.𝐜𝐨𝐦
Learn more: eu1.hubs.ly/H0h47qL0
#CART #CellTherapy #Immunotherapy
🔬DIY #Dextramer®! Create MHC Multimers in your own lab with the sensitivity and specificity that you expect from Dextramer® technology.
Learn more about U-Load Dextramer®: eu1.hubs.ly/H0h0T170
#flowcytometry #Peptides #AntigenSpecificity #Immunology #immunemonitoring
More Sensitive Detection of CAR-T Cells!
Detect More, Detect Even Low CAR Expression.
When working with CAR-T cells, sensitivity is everything.
With CAR #Dextramer®, you can detect CAR-T cells with higher sensitivity, even when CAR expression is low.
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This means:
✅ Improved accuracy
✅ Better insights into CAR-T persistence
✅ More confidence in your data
Ready to see the difference?
Contact us at [email protected] to learn more!
#CART #CARTTherapy #CellTherapy #Immunotherapy #FlowCytometry
✅ Deeper insights into immune responses
✅ Comprehensive TCR & BCR clonotype analysis
✅ Advanced single-cell multi-omics capabilities
✅ Outsource Immunophenotyping to a trusted service provider
✅ Enhanced innovation in cancer vaccines & immunotherapies
Learn more about dCODE® reagents & Parean’s services: immudex.com/about-us/news/pa…
#Partnership #ImmuneProfiling #SingleCell #Tcells #TCR #Bcells #BCR #Immunophenotyping
DIY #Dextramer®! The U-Load #Dextramer® assembly protocol (MHC I) now includes illustrative graphics for a visual workflow overview. ✔️
We recommend including the quality control assay to determine the relative peptide loading efficiency.
Download now: eu1.hubs.ly/H0gx_D80
Boosting the activity of cross-presentating type 1 dendritic cells can broaden the neoAg-specific CD8+ T cell responses and leverage these #neoantigens for therapeutic advantage.
López et al. used U-Load #Dextramer® reagents in combination with H-2 Db easYmers®
to detect neoAg-specific CD8+ T cell responses, screening a total of 26 epitopes using this technology.
Check it out from Nature article: nature.com/articles/s41467-0…
#DCtherapy #Neoantigen #immunotherapy #Celltherapy #Tcells #flowcytometry #Peptides #AntigenSpecificity #Immunology
📥Download the FDA Guidance document from the link in the comments: Considerations for the Development of Chimeric Antigen Receptor (CAR) T Cell Products (Jan 2024)👇👇
fda.gov/regulatory-informati…
#Dextramer #flowcytometry #CARTTherapy #CellTherapy #Immunotherapy #AntigenSpecificity
but also study the T cell repertoire through TCR sequencing, to ensure little to no loss of viral-reactive TCRs during the 5-day manufacturing process of their CAR-T therapy targeting T cell lymphomas.
Check out the poster abstract: ashpublications.org/blood/ar…
#Dextramer #flowcytometry #CARTTherapy #CellTherapy #Immunotherapy #AntigenSpecificity
New Year, New Color? Our immune monitoring reagents are available with BV421! 💜
MHC #Dextramer®, U-Load® and Klickmer® reagents are available as standard products with the BV421 fluorochrome.
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💡 Benefit from greater flexibility for the detection of antigen-specific T and B cells by flow cytometry.
💡 Design panels including Dextramer®-based multimers and antibodies with ease.
Learn more: immudex.com/new-colors/
#Immunology #flowcytometry #immunemonitoring
MHC #Dextramer® reagents were used in the clinical trial of IMA202 from Immatics to quantify the MAGEA1-specific T cells for dose determination
see Wermke et al., JITC 2024: jitc.bmj.com/content/12/7/e0…
🙌Read more about this milestone in our blog!
immudex.com/resources/blog/f…
#CellTherapy #Tcelltherapy #immunotherapy #flowcytometry
