Toronto, Ontario
Joined April 2016
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- Followers498
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Ismail Raslan retweeted
To any health care institution or headhunter seeking world-class physicians and surgeons, the Quebec legistlature has passed a new special law severly impacting the civil and professional liberties of medical practitioners in our province, where average remuneration was already one of the lowest in North America, in a jursidiction with one of the highest tax rates in the world. You now have the opportunity to recruit top medical talent to your institution! Quebec medical professionals are accustomed to working in a resource limited setting, in high-volume practices for discounted rates. Now's your chance to recruit and you can thank @cdube_sante, @francoislegault and the @coalitionavenir for this health care fire sale!
Ismail Raslan retweeted
Is this the end of rivaroxaban for acute VTE?
@LanaCastellucci presenting the COBBRA trial - 1st RCT comparing apixaban to riva over 3 months.
56% reduction in bleeding risk with apixaban.
A safer Rx with the same efficacy.
#ISTH2025
Ismail Raslan retweeted
Hot off the press! COBBRA trial showed that apixaban is associated with >50% reduced risk of clinically-relevant bleeding symptoms for acute VTE treatment. This can be practice changing!
@LanaCastellucci @RodgerMarc @canvector
Ismail Raslan retweeted
Three cured #sicklecell persons in one room this am. #haplobmt. Never thought I'd see the day.
Ismail Raslan retweeted
On International Day of Women and Girls in Science, learn about a unique, women-founded, multidisciplinary clinic at St. Michael’s that provides treatment, care, support and education for women with bleeding disorders – and their babies. unityhealth.to/2025/02/multi…
Ismail Raslan retweeted
Our recent study (a global collaboration) @MacDeptMed @Mac_Transfusion @NEJM @MacPlateletLab @BBS_McMasterU @McMasterIIDR @machealthsci
@McMasterU
VITT-like Monoclonal Gammopathy of Thrombotic Significance | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…
Ismail Raslan retweeted
Thrombosis rates are much higher in patients receiving high dose andexanet (as are death rates - more on efficacy in next thread)
Ismail Raslan retweeted
FDA's own review of thrombotic events reported 12 extra cases – 9 in andexanet & 3 in usual care – that were not assigned as thrombotic by blinded committee. Sorry, I don’t have more info on this!
Final figures (based on n=471 FDA safety set): 14.6% vs 6.9%, stroke 5% vs 0.4%.
Ismail Raslan retweeted
The KDIGO 2025 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD) is available for public review through Friday, November 22.
You can download the public review draft and share comments via the feedback survey on the KDIGO Anemia in CKD Guideline Website: kdigo.org/guidelines/anemia-…
KDIGO will prepare a final version for publication based on feedback received during public review. We thank you in advance for your time and insights.
#anemia #CKD
Ismail Raslan retweeted
Great presentation by Dr. @Pharmacist_MTL on the importance and relevance of @AnticoagForum Stewardship in Canada. Approx 65% of admitted patients need anticoagulation adjustments (type , dose), de-prescription of anti-platelets, etc. Avoiding complications and improving outcomes
Ismail Raslan retweeted
FcRn-targeting drugs are the new kid on the immuoheme block with many realized and potential uses in Heme and Transfusion patients
Co-authors @path_brian @jeremy et al have written an incisive review on the present and future of FcRn agents @AjHematology
doi.org/10.1002/ajh.27487
Ismail Raslan retweeted
The study (GABA-WHY) ran during his fellowship with the help of Iman Huseen and Kristen Moran, our amazing research assistants. It's published today in @JAMAInternalMed
Briefly, by giving patients these brochures, we increased deprescribing by 13%!
jamanetwork.com/journals/jam…
Ismail Raslan retweeted
Thank you @OntarioHealthOH OLMP, thank you @Dynacare, thank you @LifeLabs, thank you AlphaLabs, thank you @UofT, thank you to all members of ‘Raise the Bar’. This is a big step forward for Ontario and for 🇨🇦 Canada in promoting health equity for ppl with iron deficiency. 💥
Ismail Raslan retweeted
What to do with an ICH patient who bled while on AC for a mechanical heart valve? When and how to restart AC?
This is a cool study showing that the risk of bleeding complications far outweighs the risk of thromboembolism overall
Plus the risk of ICH is highest when IV heparin is given as a bridge to oral AC
neurology.org/doi/10.1212/WN…
Ismail Raslan retweeted
Incredibly excited to announce the official launch of our hematology education website - CBC Made Easy! Designed for all education levels, this website is a free tool to practice diagnosing various CBC abnormalities
cbcmadeeasy.com
Ismail Raslan retweeted
Not sure when to use albumin in the ICU? Check out our @accpchest commentary: mdedge.com/chestphysician/ar… @JeannieCallum @Bram_Rochwerg @m_hewitt18
Ismail Raslan retweeted
"Ferritin reference intervals are at high risk of bias" #anaemia #irondeficiency
The origin of ferritin reference intervals: a systematic review thelancet.com/journals/lanha…
Ismail Raslan retweeted
Where do guideline INR thresholds like 1.8 come from?
Is it rational to transfuse plasma to "correct" them?
In @JTHjournal, my coauthors @Ritaselby1 @jeanniecallum et al review the surprising origins of modern INR thresholds (a hint in figure below)
sciencedirect.com/science/ar…
