ALT Two panels showing the primary efficacy and safety end points. Panel A is a bar graph that shows the median number of days alive without antibiotic therapy for infective endocarditis or bacteremia within 6 months after randomization (the primary efficacy end point) among patients in the tailored-therapy and standard-therapy groups. Panel B shows the Kaplan–Meier estimates of the probability of a composite of death from any cause, unplanned cardiac surgery, or symptomatic embolic events within 6 months after randomization (the primary safety end point).