@jcpJim

Professor @scrippsresearch Chemical glycobiology, glycan binding proteins, Siglecs, influenza virus receptors

 Del Mar, CA
scripps.edu/paulson
Joined July 2017
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Predicting glycan structure from tandem mass spectrometry via deep learning #glycotime nature.com/articles/s41592-0…

Predicting glycan structure from tandem mass spectrometry via deep learning

Nature Methods - CandyCrunch is a deep learning-based tool for predicting glycan structures from tandem mass spectrometry data. The paper also introduces CandyCrumbs that automatically annotates...

nature.com
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Great to see Glycan/protein structure analysis step into the AI realm!
Glycobiology.UK@GlycobiologyUK20 Jun 2024
Highly accurate carbohydrate-binding site prediction with DeepGlycanSite nature.com/articles/s41467-0…

Highly accurate carbohydrate-binding site prediction with DeepGlycanSite

Nature Communications - Carbohydrates are essential for regulating various biological processes. Here, the authors developed DeepGlycanSite, a deep learning model that accurately predicts...

nature.com
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Jim Paulson retweeted
GlycoNet@glyconet_nce8 Dec 2023
GlycoNet is grateful to be one of the inaugural recipients of the Strategic Science Fund! @ISED_CA #Glycotime
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Well deserved Max
Max Crispin@CrispinMax17 Nov 2023
Delighted to make a third appearance on the Highly Cited Researcher list - kudos to all the lab and huge thanks to our wonderful collaborators!
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For his award lecture, Matt gave a great talk on the impact of microglial CD33 in Alzheimer's disease progression, providing insights into why it is viewed as a major risk factor in the onset of the disease.
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Congratulation to Dr Matt Macauley for being the recipient of one of the two glycobiology significant Achievement award #SFG2023
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Major step forward in understanding how glycoRNA gets made, defining the chemical linkage provides a path to bridge to biosynthetic pathways that make these glycans!
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Liquid glycan array!
Derda Lab@derda_lab28 Aug 2023
Exciting news from @tracy6528! 🎉 Check out her latest paper on 'Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays' available online now. 📚🔬 nature.com/articles/s41467-0…
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Major insight for how the conserved N-linked glycan in IgG gets sialylated, not in B cells, but in endosomal compartments of endothelial cells during recycling by the FcRn receptor!
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Jim Paulson retweeted
ACS_CARB@acs_carb29 Mar 2023
Congratulations to all our award winners: Prof Paulson (Hudson Award @jcpJim), Mia Huang (Gin Award @HuangMia), Peter Andreanna (Wolfrom) (@UToledo), Cat Grimes (@CLGrimesLab (Isbell) John/Sharon Verellotti (Horton) #glycotime
Catherine L Grimes@CLGrimesLab29 Mar 2023
Replying to @CLGrimesLab
Congratulations to all the other award winners. Carbs Rock!!!
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Agree, anxious to see if there is transmission to others, first time for H5N1 if so.
Hensley Lab@SCOTTeHENSLEY23 Feb 2023
This is not good.
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This is not good.
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The title to share scripps.edu//news-and-events…

Scripps Research polysulfates could find wide use in high-performance electronics components -...

Flexible compounds made with Nobel-winning click chemistry can be used in energy-storing capacitors at high temperatures and electric fields.

scripps.edu
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Fantastic application of SulFEx chemistry by Liu, Wu and Sharpless in materials science with potential for application in advanced electronics and batteries.
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Jim Paulson retweeted
Wolf Prize
@WolfPrize_7 Feb 2023
Congratulations to Jeffery W. Kelly, 2023 Wolf Prize laureate in Chemistry! @scrippsresearch
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S/he gets my vote!
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Took me a long time, but had a good laugh when I finally got it.
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New approach for detection of early stage cancer using glycosaminoglycans, who would have thought....
Eric Topol
@EricTopol5 Dec 2022
Very early cancer detection in healthy people has been studied with liquid biopsy tumor DNA sequencing & methylation. A new report shows the potential for free glycosaminoglycans, both plasma and urine, for 14 cancer types, especially at stage 1 pnas.org/doi/suppl/10.1073/p… @PNASNews
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Hahahahaha.... Great!
Ardem Patapoutian@ardemp6 Dec 2022
People often ask me what it is like to be a @NobelPrize laureate? @LippiLab @Alex_Chesler
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Proud to be a part of this great work, welcome to twitter @kasia_brzezicka. We can learn to tweet better together!
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