Neuropathologist @icahnmountsinai | research interests: healthy aging, #resistance to and #resilience against #alzheimers pathology, #PART | 💓 tennis, nature
New York, USA
Joined October 2010
- Tweets460
- Following862
- Followers1.6K
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Jamie Walker, MD, PhD retweeted
news from #AAIC25 marks a moment so many of us in the Alzheimer’s and dementia scientific community have long hoped for. We can now say with confidence that lifestyle interventions can protect brain health in diverse communities in the U.S.
📣 Today is a turning point in what we know about brain health.
The results from the U.S. POINTER trial provide the rigorous data needed to say with confidence that healthy behaviors can meaningfully protect brain health across diverse populations in the U.S.
The findings, shared for the first time today at #AAIC25, tested lifestyle programs that simultaneously targeted risk factors. The programs focused on:
✅👟Aerobic exercise
✅🧠Cognitive engagement
✅🥗Nutrition
✅🫀Health Monitoring
U.S. POINTER is the largest research commitment the Association has made in its history. The landmark results are testament to our commitment to our mission. Thank you to the study participants, our community, our donors, and the staff who made these findings possible.
alz.org/USPOINTERresults
Jamie Walker, MD, PhD retweeted
‼️Alert‼️Massive open dataset release!!
The world’s largest proteomics dataset for neurodegenerative disease, including:
* 250M+ protein measurements
* 35,000 biosamples
* 23 contributing cohorts
* +50 harmonized clinical variables
* AD / PD / FTD / ALS / Normal Aging
1/
Analyses from the largest neurodegeneration focused proteomics database - the Global Neurodegeneration Proteomics Consortium @_neuroproteome are published today in @NatureMedicine and @NatureAging
The findings reveal unique protein biomarkers that correlate with @neurodegenerative diseases and the @ageing process, and may help with the early detection, and improve outcomes, of major neurodegenerative diseases.
Read the collection here: nature.com/collections/ecege…
Jamie Walker, MD, PhD retweeted
Rare functional variants in IGF-1 gene found in people with exceptional longevity nature.com/articles/s41598-0…
@AmanatA32448955 @EinsteinMed @NirBarzilaiMD @AFARorg @NaturePortfolio @EinsteinAging
Jamie Walker, MD, PhD retweeted
We were proud to recognize our 2025 #RainwaterPrize winners, Dr. Kaj Blennow and Dr. @bess_frost, at #Tau2025. Thank you to everyone who helped celebrate their groundbreaking contributions to tauopathy research. Explore the impact of the prize.
Thank you #ADPD2025 for a wonderful conference in Vienna! Congrats to @SusanRohde_ on her junior faculty award and fantastic presentation! 🤩
Jamie Walker, MD, PhD retweeted
Had such a great and inspiring time at #ADPD2025 in the beautiful Vienna. Thanks for all the great science, inspiring chats and new people I've met. This week was good for my scientific spirit! 🧠✨
Jamie Walker, MD, PhD retweeted
Super impressed by the clarity and thoroughness of the rising star @SusanRohde_ #ADPD2025 #neuropathology presentation. Brava 👏👏👏
@amsterdamumc – at Vienna, Austria
Jamie Walker, MD, PhD retweeted
Very proud to have received a Junior Faculty Award at #ADPD2025. On Fri April 4th at 14.30 I will talk about hippocampal pathology in centenarians. I hope to see you there! – at Vienna, Austria
Jamie Walker, MD, PhD retweeted
PLEASE HELP SHARING - LOOKING FOR POST-DOCS to study the basis of sleep and circadian dysfunction in Alzheimer's and related diseases. bit.ly/4hfP4cd @ISTAART @NSS_PIA @ResearchSleep @SleepPIA
Jamie Walker, MD, PhD retweeted
TODAY! Wake up (sleep is very important for brain health!), enjoy a good🥚(what food supports brain function?), have a cup of☕️ (Is coffee really good for your brain?) & head over to the Guggenheim Pavilion where the #BrainAwarenessWeek BRAIN FAIR will definitely boost your mood!
Valentine’s brains! 🧠 💕 Diagnoses: heartocephalus, glioheartoma, neurosyphilove, Alzhearter’s (heart plaques and confetti sprinkle tangles) #neuropath #neuroscience #neurology #brainlove #valenbrains
Jamie Walker, MD, PhD retweeted
It’s an honor to be awarded the @RCFNeuro 2025 Innovative Early-Career Scientist award! My team and I are excited to continue pushing the envelope to unravel mechanisms underlying tau toxicity and to translate our discoveries into therapeutic strategies to combat tauopathies.
Jamie Walker, MD, PhD retweeted
Brain Moss💚The @TsankovaLab's Dr. Melissa Umphlett has created incredible moss "wall art" using preserved🦌reindeer & pillow moss on wood. VOTE NOW for #ArtoftheBrain Image #18 Most💙s wins! #BAW2025 View the 2024 Art of the Brain virtual exhibition: neuroscience.mssm.edu/artoft…
AD, PART and CTE share the same 3R/4R-tau+ NFTs, but in a different distribution … what about their proteomes? Excited to share our spatial proteomics study comparing #Alzheimers, #PART and #CTE hippocampi doi.org/10.1002/alz.14487 #neuropath #neuroscience #neurology #proteomics
PART and CTE display several similarities in protein expression that are distinct from AD, perhaps in relation to lower levels of beta-amyloid … which could be secondary to the maintenance of expression of proteins involved in proteostasis and beta-amyloid processing.
Jamie Walker, MD, PhD retweeted
Major messages of our recent paper: Neurodegenerative proteins affect different subregions of the hippocampus; copathology alters the pattern; The load of protein increase until a peak but in the highest stages it decreases with the loss of neurons. See: doi.org/10.1002/alz.14355
