Postdoc @lydfinley lab @MSKCancerCenter interested in cellular metabolism and mitochondria 🧫 | Previously PhD @Cambridge_Uni @IMS_MRL
New York
Joined November 2018
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Beyond excited to share my first paper from my PhD @DPhaz Lab @IMS_MRL now out in @embojournal! Special thanks to Sam from @TVPLab and @dougall_norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:
embopress.org/doi/full/10.10…
Joycelyn Tan retweeted
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.
Joycelyn Tan retweeted
Reasons to use an em dash:
1) reclaim it from the machines
2) you don't know what a semicolon is for
3) it has incredible vibes
Joycelyn Tan retweeted
Out today in @cellcellpress new work from the lab led by Abby Xie and @jules_stef asks, when and why do cells use the TCA cycle?
Joycelyn Tan retweeted
Online Now: Aspartate availability drives differential engagement of the malate-aspartate shuttle dlvr.it/TRB143
Joycelyn Tan retweeted
I'm excited to share our latest story from the @lydfinley lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used . Out now in @NatMetabolism: rdcu.be/ejFTs 1/
Joycelyn Tan retweeted
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. jobs.cam.ac.uk/job/50597/ @IMS_MRL Please RT. Please email if interested.
Joycelyn Tan retweeted
Very excited to finally share our work using subcellular proteomics to look at insulin-stimulated protein movement in adipocytes! 🧵below: (1/5)
biorxiv.org/content/10.1101/…
@DPhaz @IMS_MRL
Excited to share our opinion piece on why current standard cell culture practices deserve more consideration - with implications on cell metabolism and beyond! We focus in particular on nutrient and oxygen availability. A pleasure to work with @JasonRCantor lab! @DPhaz @IMS_MRL
happy to share our forum now online @Cell_Metabolism! fun for us (@guytochondria & myself) to collaborate with @DPhaz @joycelyntsi, and Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling!
cell.com/cell-metabolism/ful…
Joycelyn Tan retweeted
Our latest preprint identifies (targetable!) metabolic programs intrinsic to different cancer cell states in rhabdomyosarcoma, out just in time for @kiparas21's thesis defense tomorrow!
PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma biorxiv.org/cgi/content/shor… #biorxiv_cancer
Joycelyn Tan retweeted
no PhD in history has ever needed to say this before
Joycelyn Tan retweeted
Oncometabolites at the crossroads of genetic, epigenetic and ecological alterations in cancer
nature.com/articles/s41418-0…
Joycelyn Tan retweeted
Check out this #Resipher feature on @TheScientistLLC! It outlines the experience that @joycelyntsi, cellular biologist at Memorial Sloan Kettering Cancer Center, had with using the device to measure #OxygenConsumption rate.
the-scientist.com/a-simple-c…
Joycelyn Tan retweeted
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Joycelyn Tan retweeted
Hi #cancer #metabolism twitter. New review from @CognetGuillaume: science.org/doi/10.1126/scia….
Has long been understood that tumors experience metabolic stress due to nutrient limitation in the tumor microenvironment. 1/7
Joycelyn Tan retweeted
Postdocs: we want to start a NYC "Postdoc Night Science" forum where fellows meet monthly for a drink and fun practicing the creative process together with chalk talks and brainstorming. Sign up here: docs.google.com/forms/d/1V4_…
@KelseyRMonson is helping and we need more volunteers!
Joycelyn Tan retweeted
Imagine seeing a disease's impact on every cell in the body. Now, you can!
We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. MouseMapper showed obesity-induced changes in facial nerves & body-wide inflammation 👉🏼🧵biorxiv.org/content/10.1101/…
Joycelyn Tan retweeted
We are looking for a Postdoc to investigate novel genes that regulate insulin-stimulated glucose transport (tinyurl.com/ycarykzh). MRC-funded collaboration with O'Rahilly (@StephenORahilly) @IMS_MRL & Langenberg groups (QMUL).
Please RT.
Link: tinyurl.com/57ea9p3f