The evo-devo of skin. Penn Genetics. Penn Derm.
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Joined September 2022
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New ppr in @Dev_Cell in which we flip skin fate from sweat gland to hair follicle to uncover the instructive sweat gland niche and the developmental signature of sweat gland identity. Congrats @dingwallaby and the team! @PennSbdrc @PennGenetics @IRM_UPenn doi.org/10.1016/j.devcel.202…
"How the skin got its sweat". Our new paper just went live. Sweat gland development requires an eccrine dermal niche and couples t... sciencedirect.com/science/ar…
kamberovlab retweeted
We also had Prizes! Denay Richards (Devenport Lab, @Princeton) won Best Short Talk. Best Poster Prizes were awarded to Dr. Dingwall (@kamberovlab, UPenn) and Dr. Wang (@RendlLab, @IcahnMountSinai). Congratulations!
We are recruiting a post-doc to work in regenerative and evolutionary biology of human skin! jobrxiv.org/job/university-o…
kamberovlab retweeted
A transient dermal niche and dual epidermal programs underlie sweat gland development biorxiv.org/cgi/content/shor… #bioRxiv
Our "coolest" new preprint is up! Classic genetics + single transcriptomics = a novel niche and a recipe for identity of the eccrine gland...humans' indispensable thermoregulatory organ. Congrats @dingwallaby and all the team! biorxiv.org/content/10.1101/…
ALT A transient dermal niche and dual epidermal programs underlie sweat gland development https://www.biorxiv.org/content/10.1101/2023.04.15.537037v1
New paper is out! The "Ectodysplasin" road less traveled...and the importance of genetic background! Ectodysplasin signaling via Xedar is required for mammary gland morpho... sciencedirect.com/science/ar… Congrats @abbywark @dialdea #Reiko Tomizawa @PennSbdrc @PennGenetics
Mind how you sweat! Enhancer pleiotropy shapes how an adaptive trait evolved. Even made a model! Our new paper is out in PLoS Genetics! journals.plos.org/plosgeneti…
kamberovlab retweeted
Excited to share the preprint of my latest work. Wonder how oncogenic Kras disrupts tissue architecture? We find it does so through converting pulsatile into sustained ERK activation! Thank my mentor @valentatormenta, collaborator @RegotLab and other authors!
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation biorxiv.org/cgi/content/shor… #bioRxiv
New preprint: Mind how you sweat! Pleiotropic brain enhancer shapes how sweat glands evolve. Awesome work from @dialdea @dingwallaby Blerina Kokalari with help from Cotsarelis lab and Yuji Atsuta! @PennGenetics @PennSbdrc
biorxiv.org/content/10.1101/…
