Molecular_Streamer (@kemmishTree) header
Molecular_Streamer (@kemmishTree) profile picture

https://teapawt.org/t.co/y7NyrcmhXe

Joined March 2025
Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)Photo by Molecular_Streamer (@kemmishTree)
Everybody's racing the build the brains, we're building the eyes.
43
Molecular_Streamer retweeted
Replying to @atmoio
Yeah, this is fucking bleak but accurate. There's an entire generation—maybe multiple generations now—of people who have NEVER experienced what it's like to be embedded in a multi-generational community. They've never lived in a context where: - You have elders who pass down practical wisdom - You participate in the raising of families even if they're not biologically yours (nieces, nephews, neighbors, community care overall) - You witness the full human lifecycle regularly—births, marriages, deaths - You have intergenerational knowledge transfer happening organically They literally don't know what they're missing because they've NEVER EXPERIENCED IT. It's not even nostalgia for them—it's a complete absence. They have no reference point for what community embedded in family structures even feels like. No visceral memory of what it's like to be part of something multi-generational and ongoing. And because they don't know what's missing, they can't even name the void. They just feel this ambient emptiness, this sense that something is fundamentally wrong, but they don't have language for it. So they fill it with: - Hobbies (mostly non-human centered activities) - Career achievement (jobs that are mostly bullshit and provide almost no meaning) - Parasocial relationships (streamers, podcasts, online communities that simulate connection) - Pets (great but are also filling a void that used to be filled by human relationships) - Substances, screens, whatever numbs the ache And the truly fucked part is: **they have no knowledge to pass down** because they never received any. The chain is broken. They don't have practical skills, community wisdom, relational knowledge to give to the next generation because no one gave it to them. So even if they WANTED to create families or communities, they wouldn't know how. They're working from scratch with no blueprint. It's generational amnesia. An entire cohort of people who've been raised in isolation, who've never witnessed or participated in the basic human pattern of "elders teach the middle generation who raise the young generation," so now you just have... isolated individuals aging in parallel, no one teaching anyone anything, no one raising anyone, no continuity, no meaning, just waiting. Waiting for what? They don't even know. Just... scrolling until death, basically. Filling time between birth and death with distractions because the thing that used to give life structure and meaning—being part of an ongoing multi-generational community project—has been completely obliterated. And capitalism LOVES this because atomized individuals are perfect consumers. They have to buy everything because they can't rely on community. They have to pay for childcare because there's no one helping, for entertainment because there's no community gatherings, for therapy because there's no elders offering wisdom. They have to pay for everything that used to be provided by embedded social relationships. The percentage of people living like this? In major cities, among educated professionals, especially in their 20s-30s? I'd say it's probably 40-60% at MINIMUM. Huge swaths of people who have never lived in a context where they regularly interacted with different generations on a meaningful level, participated in family formation, or experienced what it's like to be part of something that went beyond their immediate friends or family. And the saddest part? Most of them don't even realize how abnormal this should be if society gave a shit about human well-being. They think THIS emotionally illiterate hellscape is just how life is. They have no idea that for most of human history, people lived completely differently—embedded in community, surrounded by families, constantly participating in the raising of the next generation. That's been almost deleted from memory. Erased. Replaced with "this is just modern life, get used to it." It's a mass-scale human deprivation experiment presented as progress.
1
1
7
919
Molecular_Streamer retweeted
Replying to @atmoio
i've been reading a mix of older stuff, some serious some not, little bit of plutarch, little bit of agatha christie, it's nice and then i read this site i guess, where it feels like i'm on page one million of the world's worst novel
1
9
1,048
Molecular_Streamer retweeted
Protein Data Bank (PDB) is 55 years old btw
1
4
2
57
3,191
Molecular_Streamer retweeted
You have to hand it to Heidi Klum. Every year she delivers. She takes the assignment seriously.
102
235
37
3,900
228,597
Molecular_Streamer retweeted
ハロウィンの「逆ビョーク」の仮装
514
26,725
1,184
461,578
7,839,791
Molecular_Streamer retweeted
>be CNRS scientist in montpellier >dig through institut curie's chemical library looking for an HIV cure >find a quinoline that blocks rev from exporting viral RNA >somehow involved in splicing >start a company called splicos based on this >4 years later, company gets merged into abivax >molecule is now ABX464 >run two phase 2a HIV trials >it shrinks the viral reservoir a bit >mfw "a bit" does not cure HIV >but the bloodwork is weird >random microRNA miR-124 is cranked tf up >mfw miR-124 is a major chill pill for inflammation >turns out the drug grabs the cap-binding complex and splices exactly one random lncRNA >that lncRNA becomes miR-124 >why that one? lol idk >HIV attacks GI tract, so maybe give it to colitic mice? >guts heal lmao >let's yolo this for ulcerative colitis >2018 phase 2a works >let's try with rheumatoid arthritis while we're at this >2020 covid hits >"what if it stops cytokine storms" >yeah let's cure ARDS too lol >french gov makes it a national research priority >500 patients in >2021 trial stopped, does nothing >stock eats dirt >ceo: "covid was hyper-acute, chronic inflammation is different, trust me" >quietly drop rheumatoid arthritis >go all in on UC >phase 2b works >2025 phase 3 induction hits >stock goes vertical >2026 maintenance trial: half get remission on drug vs 10 % on placebo >placebo rate is the lowest ever seen in a trial like this >NDA to FDA planned late 2026 >mfw a failed HIV drug, a failed covid drug, and a lucky lncRNA might become a blockbuster UC pill >mfw it took 18 years
>mfw >biology is just a data problem >run gwas to find causal genes >find strong risk locus for heart disease >it's a gene desert at 9p21 >only thing nearby is a lncRNA called anril >was found with dels in a melanoma family not in heart patients >antisense to cdkn2b >~20 exons, dozens of isoforms, linear and circular >primate-only, no anril in mouse >delete the region in mice, get a phenotype anyway >maybe the DNA is an enhancer >risk snps break stat1 binding sites >linear anril recruits polycomb to silence p15/p16 next door >also travels the genome and docks on alu repeats?? >circular anril binds pes1, jams ribosome assembly >kills overgrowing plaque cells >risk allele shifts the ratio from circular to linear >same exons, opposite effects >also linked to diabetes, aneurysms, glaucoma, gum disease, cancer >cancer papers say it sponges every miRNA you can name >open my cell model schema >gene_type: lncRNA, enhancer, maybe >topology: linear, circular >mechanism: cis, trans, depends which isoform you ask >effect: pro-atherogenic, protective >conserved: lmao
4
6
2
73
4,097
Molecular_Streamer retweeted
genuine william shakespeare level writing with this one
I still think of this vid on the daily I know everyone says "Ed, Edd n Eddy been canceled for years that's why I'm confused." but this is my favorite of his easily
63
2,115
77
17,111
357,641
Biology is Just Beginning.
>mfw >biology is just a data problem >run gwas to find causal genes >find strong risk locus for heart disease >it's a gene desert at 9p21 >only thing nearby is a lncRNA called anril >was found with dels in a melanoma family not in heart patients >antisense to cdkn2b >~20 exons, dozens of isoforms, linear and circular >primate-only, no anril in mouse >delete the region in mice, get a phenotype anyway >maybe the DNA is an enhancer >risk snps break stat1 binding sites >linear anril recruits polycomb to silence p15/p16 next door >also travels the genome and docks on alu repeats?? >circular anril binds pes1, jams ribosome assembly >kills overgrowing plaque cells >risk allele shifts the ratio from circular to linear >same exons, opposite effects >also linked to diabetes, aneurysms, glaucoma, gum disease, cancer >cancer papers say it sponges every miRNA you can name >open my cell model schema >gene_type: lncRNA, enhancer, maybe >topology: linear, circular >mechanism: cis, trans, depends which isoform you ask >effect: pro-atherogenic, protective >conserved: lmao
36
Molecular_Streamer retweeted
mfw >biology is just a data problem >collect enough omics, simulate the whole cell >read about humanin >peptide encoded inside the mitochondrial 16S rRNA gene >the same sequence is also a structural part of the ribosome >24 aa if the cytosol translates it, 21 aa if the mitochondria do >because mitochondria run a different genetic code >and start translation with N-formylmethionine instead of plain methionine >nobody's fully sure which one actually makes it >also 13 nuclear copies that might make their own versions >gets secreted into the blood >hits cell-surface receptors >one of them is literally a mitochondria detector >also gets taken back up >binds Bax inside the cell to block apoptosis >discovered by screening surviving brain tissue from an alzheimer's patient >open my cell model schema >compartment: yes >molecule_type: rRNA, peptide, hormone >length: depends who's asking
23
40
10
431
38,422
Molecular_Streamer retweeted
The Singularity is coming for Physics and Biology. RIP Math.
105
653
113
6,892
638,197
Molecular_Streamer retweeted
You Can See Everything w/ Jamie Lee Curtis 🤣 #FallonTonight
336
1,582
573
37,428
9,347,632
Molecular_Streamer retweeted
I always thought this was one of the funniest videos on the internet. Sharing acting wisdom. Rubbing his partner’s feet. High as a kite. I’ll miss ya, legend
8
280
18
2,191
58,174
Molecular_Streamer retweeted
This is why the axe is technically a lab instrument
4
5
53
1,927
Molecular_Streamer retweeted
Replying to @kemmishTree
he's like jack lalanne for terminally online men
1
1
34
Molecular_Streamer retweeted
When this conversation comes up, I always go back to this really succinct quote from Fran Lebowitz.
There's a lot of gay ppl doing culture commentary now who do not know cultural references beyond the ones that have been memes on the internet. In previous generations being gay in that space was all about being a nerd about cultural minutiae of the past. That was the foundation
66
1,674
145
15,243
458,587
Molecular_Streamer retweeted
Just a reminder: it is still October.
5
15
1
171
15,914
Molecular_Streamer retweeted
Replying to @andrewchen
shit we're 0 for 4...can we add 1 more: ☑️ solo founders ☑️ non-technical founders ☑️ domain expert with no tech experience ☑️ content creator whose new content is "apps" ✅ star of independent remake of Caddyshack
1
1
226
Molecular_Streamer retweeted
2
46
2
758
24,338
I'm gonna rent theaters for private invite-only Rocky Horror Picture Show style viewings of this in which screaming will be encouraged. DM me for an invite if you're in NYC, Boston, or SF.
Okay I lost it at the part where Elizabeth Holmes tried to explain her magic biomarker assay machine by telling Nathan that it worked by connecting to the CLOUD(MAGIC IN THE SKY PANACEA)AND THE CLOUD GIVES IT ADAPTIVE INSTRUCTIONS and the device is a platform that is theory capable of running any test(provided the chemistries for the tests are developed) sorry I can't forgive this film
4
355