Sir Henry Dale Fellow, King's College London. Interested in proteins and their post-translational modifications.
London
Joined September 2019
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ManuelMuellerLab retweeted
Semisynthesis of Isomerized Histone H4 Reveals Robustness and Vulnerability of Chromatin toward Molecular Aging | Journal of the American Chemical Society
@KingsCollegeLon
pubs.acs.org/doi/10.1021/jac…
Thrilled to announce our group's latest paper in @J_A_C_S: Semisynthesis of Isomerized Histone H4 Reveals Robustness and Vulnerability of Chromatin toward Molecular Aging | Journal of the American Chemical Society pubs.acs.org/doi/full/10.102…
We chemically synthesized old histones containing an isoAspartate residue to measure the impact of aging on chromatin integrity. We found that chromatin is surprisingly tolerant of this particular form of wear-and-tear, although local perturbations were observed.
Congratulations co-1st authors @_TianzeZhang & Luis Guerra @kclchemistry and great collaboration with Iana @Beatfierz and Jon.
ManuelMuellerLab retweeted
Check out this fully funded PhD studentship on peptidomimetics available in the Wilson group. findaphd.com/phds/project/pe…
ManuelMuellerLab retweeted
I have an AstraZeneca-funded PhD position available (4 years), based in my lab (School of Chemistry, University of Nottingham); start date Oct 2025!
Traceless Chemoenzymatic Peptide Synthesis
Application deadline: 6 Jan 2025. Get in touch!!!
findaphd.com/phds/project/tr…
ManuelMuellerLab retweeted
Come and join my group @TheCrick - we have a PhD tinyurl.com/rhtfbdx4 in metal-peptidic cages and high affinity binders, and will advertise a 3 year PDRA in December for a Chemical Biologist with synthetic and cell work experience. Email if interested, retweets appreciated!
ManuelMuellerLab retweeted
Kinetic Resolution of Epimeric Proteins Enables Stereoselective Chemical Mutagenesis | Journal of the American Chemical Society @kclchemistry @KingsCollegeLon #Kinetic #Resolution #Epimeric #Proteins #Stereoselective #Chemical #Mutagenesis pubs.acs.org/doi/10.1021/jac…
Led by PhD student Guljannat, we introduced a kinetic resolution step to dehydroalanine chemistry. By cleaving the D-amino acid-containing isomer with a D-peptidase, we combine the stereoselectivity of enzymes with the broad scope of chemo-selective Dha functionalisation.
ManuelMuellerLab retweeted
A new scholarship is available to next year's MRes Chemistry students - apply by 31 August.
The Mackenzie Family Scholarship established in the memory of Mr F.H. Mackenzie is a prestigious award covering a £22,000 stipend ⚗️
Find out more 🔗⬇️
loom.ly/72FInaE
ManuelMuellerLab retweeted
Excited about engineering powerful biocatalysts? Check out the open PhD position in my group!
👉zhaw.ch/en/jobs/vacant-posit…
Please spread the word!🇨🇭🏔️🧪🌿☀️
@NCCR_Catalysis @ZHAW
Photo: ZHAW Wädenswil / Frank Brüderli
ManuelMuellerLab retweeted
Late breaking PhD project to work with me and Charlie on mass spec crosslinking in heart disease! To start by Jan 2025. UK fees only, apply by 9th August.
Fully-funded EPSRC PhD opportunity @UoL_LICAMM @AstburyCentre developing live-cell chemical cross linking methods to study myosin folding and disease with myself and @MWrightLab phd.leeds.ac.uk/project/1985… apply by 9th August
ManuelMuellerLab retweeted
🌟 Join Our Team! 🌟 We're seeking a talented #postdoc to join us @kclchemistry! Come and explore membraneless organelles, molecular conformations, and enzyme activity with us.
3-year post. Deadline extended to June 30.
kcl.ac.uk/jobs/089765-postdo…
ManuelMuellerLab retweeted
Rapid Peptide Cyclization Inspired by the Modular Logic of Nonribosomal Peptide Synthetases | Journal of the American Chemical Society @KingsCollegeLon #Peptide #Cyclization #Modular #Logic #Nonribosomal #Synthetases pubs.acs.org/doi/10.1021/jac…
ManuelMuellerLab retweeted
Interested in finding out how aldehydes cause ageing?
Check out this exciting new PhD opportunity in the Hopkinson Group.
findaphd.com/phds/project/ev…
DEADLINE = 23rd May 2024.
You can apply directly here:
le.ac.uk/study/research-degr…
ManuelMuellerLab retweeted
We are hiring! We look for Postdocs in the field of biophysics / chemical biology of gene regulation within a context of a SNSF Advanced Grant starting in 2024! More details here: epfl.ch/schools/sb/research/…
ManuelMuellerLab retweeted
Make sure to get your applications in by 3rd of March if you are interested in joining us through this fully funded studentship opportunity with @KawamuraGroup
@SciencesNCL @ChemistryNCL @DurhamChemistry
📣 Applications now open for a funded #PhD #chemicalbiology #cyclicpeptides. Exciting opportunity for doctoral research with the Kawamura Research Group and @MosmedC at Newcastle Uni @ChemistryNCL, in collaboration with @novonordisk.
More information: ncl.ac.uk/postgraduate/fees-…
ManuelMuellerLab retweeted
4-year studentship available in my lab at @kclchemistry working at the interface of fundamental synthetic biology and therapeutic biotechnology development - come & join me in the XNA world! Please RT
findaphd.com/phds/project/ch…