We are the Öst lab at Linköping University, focusing on how diet influences sncRNA and the epigenome in both fly and human sperm and embryo 🧬

Linköping, Sverige
Joined October 2019
Cool study that I’ve had the honour to highlight with a News&Views piece. More evidence that paternal pre conceptional “life” is relevant to at least two generations. Thanks for the highlight @EricTopol
Fascinating. Why it may be good to be conceived in the cold winter season. More brown fat (which is really good) as an adult. nature.com/articles/s42255-0… nature.com/articles/s42255-0…
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Very interesting read. nature.com/articles/s41467-0…
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We are very happy that our paper was selected as the best paper in Antioxidants and Redox Signaling 2023 liebertpub.com/doi/full/10.1…, and we are honoured to be a recipient of the Rosalind Franklin Society RFS Science award 🙏 A tread about our paper 🧵 1/6
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This hypothesis was strengthened by a recent work Teperino team @epi_tep published in Nature nature.com/articles/s41586-0…. 5/6
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Thanks to all team members, especially @Signe Skog, Rashmi Ramesh and Unn Kugelberg, and to the ones that financed our research @KAWstiftelsen @Stiftelse @Vetenskapsradet 6/6
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Congrats Raf!!
Thrilled and extremely excited to share our ms published today @Nature 👇👇 a thread 🧵 will follow soon … stay tuned 💪💪 #epigenetics #spermatozoa #development #diabetes #obesity #inheritance
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Save the date! This year I will be participating to Pint of Science! 🗓 13-15th May 📍 Linköping, Sweden Ever wondered how your mindset influences your health? Grab a beer and join me the 14th of May to know the answer! See you all there! 🍺🧠🔬 #pint24 @liu_universitet
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ÖstLab retweeted
The 5’ end cap structure is critical for the innate immune sensors, IFIT1, IFIT5 and RIG-I to discriminate between self and nonself RNAs bit.ly/3uwsfP4
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Our PhD student Lovisa Örkenby just presented her thesis and is now defending it in excellent scientific discussion about early Drosophila development with opponent @Iovino_Lab from Max Planck Institute!
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Why has obesity prevalence been increasing? Despite much research and sometimes angry debate, we really don't know, as detailed in this perspective I wrote @Cell_Metabolism. Let's focus on mechanisms, individual variability & actionable interventions. urldefense.proofpoint.com/v2…
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Doomed from the start? In this paper, Ph.D. student Lovisa set out to study how stress during a sensitive time point in early development affects the transcriptome - now online at Molecular Systems Biology!  doi.org/10.15252/msb.2022111… 🧵 (1/5)
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Finally, we found that knockdown of any of the members of the Elba complex family mimicked the effect of early heat shock, and Elba1-3 acts as Su(var)s for wm4h. (5/5)
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We want to thank @Vetenskapsradet, @KAWstiftelse, and @stiftelse for the funding of this work that made it possible, as well as all authors and collaborators!
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Very nice work on the early transcription in Drosophila embryos. Well done Heidi!
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