@lihaone

PI @XJTU1896, Postdoc @MDC_Berlin, PhD @epfl_en.

 China
Joined September 2015
  • Tweets35
  • Following171
  • Followers53
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We are looking for a skilled lab technician to contribute to our upcoming one-year lysosome project. Interested? Apply now and help us unlock new discoveries! werkenbij.amsterdamumc.org/e…
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Announcement: @epflSV is seeking candidates for a tenure-track assistant professor in #metabolism. For more information: epfl.ch/about/working/profes…
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New! Online now: Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis dlvr.it/SYGkB1

Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis

Li et al. use the BXD mouse reference population to evaluate how genetics and diet regulate bile acid homeostasis. Through this integrated systems genetics approach, they mapped hundreds of genetic...

cell.com
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Excited to share our recent work studying the genetic and dietary (food & feeding) modulators of bile acids using mouse systems genetics. We explored the associations between BAs and the metabolic performance of these mice, and identified many genetic loci that regulate BAs. 1/3
Schoonjans Lab@SchoonjansLab12 Sep 2022
Online now! Our work on how #genetic and #diet control #bileacid homeostasis and metabolism is out @Cell_Metabolism. Congrats @lihaone and @alessiaperino! You can explore this extensive resource at: systems-genetics.org/BXD_BA cell.com/cell-metabolism/ful…
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In particular, we identified and experimentally validated Ces1c as a previously uncharacterized modulator gene for plasma tauroursodeoxycholic acid (TUDCA), which is the major component (up to 70%) in bear bile and is known to have beneficial effects in multiple diseases. 2/3
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A big thanks to all who contributed, particularly my mentors @SchoonjansLab @Auwerx_Lab, and @alessiaperino @huangqingyao @giacomo_von, Amir, Laura, Karim, Melanie, @m_bousleiman Jéromine, Yu, Xiaoxu, Alexis, @LudgerGoeminne @HGallartAyala Evan, and @JuliJivanisevic. 3/3
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The #SchoonjansLab is looking for a highly motivated post-doc to run a project involving #CancerStemCell, #miRNAs, #lncRNAs, and #NuclearReceptors. Prospective candidates should have prior experience in at least one of these fields. Send application to: [email protected]
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A thread on epistasis, GWAS polygenic risk scores, precision medicine, the simple joys of N-equals-1 science (neuroscience in particular), and the NIH BRAIN Initiative with a few sharp edges, but love all around @on_BRAINini @ibangs @NIMHDirector @jonathan_flint1 @moorejh 1/17
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Congrats to Johan Auwerx ranked #73 in the world ranking (#2 in Switzerland) of the top 1000 #scientists in #Biology and #Biochemistry for 2022 research.com/scientists-rank… research.com/scientists-rank…

World's Best Biology and Biochemistry Scientists: H-Index Biology and Biochemistry Science Ranking...

Compare the best scientists in Biology and Biochemistry for 2026. Discover Research.com annual Best Biology and Biochemistry Scientists

research.com
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Please RT: my department (Center for Integrative Genomics, University of Lausanne) has an open Tenure-track Assistant Professorship position. Broad call; generous support, and hard to beat Switzerland as place to work + live. career012.successfactors.eu/…
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We are hiring a #PhD student in #lausanne to work on muscle stem cells, metabolism and aging at NIHS and @epflSV @EPFL_en Apply here epfl.ch/education/phd/edbb-b… Please RT 🎓🔬🧬🧫
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We're looking for BSc/MSc students (Germany/abroad) from bio/med/physics/CS to join our interdisciplinary, research-oriented QTeam on single-cell sequencing data analysis at Humboldt-Universität Berlin! Course description and application: bit.ly/organoids_qteams
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Honored to be awarded the @EMBO postdoctoral fellowship to work on spatial transcriptomics in @N_Rajewsky lab @BIMSB_MDC @MDC_Berlin.
EMBO Fellows@EMBOFellows14 Jun 2021
We are excited to announce the 112 awarded @EMBO Postdoctoral Fellowships, listed here: embo.org/funding/fellowships… Feel free to share the happiness and send us a picture how you celebrate!
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Our latest review on aging and age-related disease. We discuss the role of mitochondrial dynamics, ie fusion/fission. Great work by @YasmineJLiu and @r_l_mcintyre! Stay tuned for some experimental science in this domain 😬. For now, see sciencedirect.com/science/ar… – at Amsterdam, The Netherlands
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Check out our review on the use of mouse systems genetics to promote precision medicine with @lihaone @TrendsGenetics. #openaccess cell.com/trends/genetics/ful…

Mouse Systems Genetics as a Prelude to Precision Medicine

Mouse models have been instrumental in understanding human disease biology and proposing possible new treatments. The precise control of the environment and genetic composition of mice allows more...

cell.com
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Another example showing the predictive power of GeneBridge. systems-genetics.org/modules…
bioRxiv@biorxivpreprint13 Dec 2019
YBEY is an essential biogenesis factor for mitochondrial ribosomes biorxiv.org/cgi/content/shor… #bioRxiv
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A #BigData toolkit to mine the dark genome for #precisionmedicine actu.epfl.ch/news/big-data-t… | New paper from @Auwerx_Lab in @genomeresearch
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Big data toolkit to mine the dark genome for precision medicine actu.epfl.ch/news/big-data-t… #epfl
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Predict the function of your gene using big data at systems-genetics.org. Check our new paper @genomeresearch. genome.cshlp.org/cgi/content…
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Predict gene function using our new systems tools at systems-genetics.org. Check out the preprint from @Auwerx_Lab.
bioRxiv@biorxivpreprint25 May 2019
Identifying gene function and module connections by the integration of multi-species expression compendia biorxiv.org/cgi/content/shor… #bioRxiv
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