@maxhodak_

better living through technology

maxhodak.com
Joined March 2009
  • Tweets4.5K
  • Following828
  • Followers38.1K
435Media
til windows doesn't even support automatic light/dark mode switching out of the box. barbarians
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in the end, it wasn't too cheap to meter lol in fact it turns out it is carefully metered
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the fact that tens of thousands of people are taking research grade peptides and there have been essentially zero issues relating to CMC-type problems is a huge indictment of compassionate use / expanded access controls
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right now it doesn't matter if you're making an experimental drug for one very sick patient or mass manufacturing it for thousands: the manufacturing controls are the same, and this is the difference between $3M+ and <$50K manufacturing costs
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but tons of people are doing it anyway and so we know _empirically_ that these policies are bad! urge your member of congress to include reform on this, and other related issues, as part of the Prescription Drug User Fee Act reauthorization bill happening next year
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secret, held-out test suites seem really effective at forcing models to write fundamentally stronger code
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a little tough to reconcile the fact that my metaphysics (dual aspect monism) more or less prohibits zombies with the idea that in practical terms I probably talk to them every day
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wake up babe our new spines arrived
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Max Hodak retweeted
Doris Tsao
@doristsaoOct 2
My top advice for anyone devising a theory of consciousness: Stop philosophizing and go use your theory to build something that will help humanity. Newton’s theory of gravity led to space travel & GPS. If you have a true theory of consciousness, what human limit will you not be able to transcend? #AsteraNeuro
Henry Shevlin
@dioscuriOct 2
On a serious note, my top advice for anyone devising a theory of consciousness (besides “don’t”): learn the existing landscape and where your view fits. Which theories are closest? What does yours improve on? How does it handle the standard objections to those theories?
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the way AI has increased the opportunity cost of my time is insane definitely both a blessing and a curse
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Frank G. Holz, MD, Armin Wolf, MD, and Boris Stanzel, MD, PhD, will present “PRIMA Retinal Implant in Geographic Atrophy: From Pivotal Trial Data to the Clinic” today at DOG Deutsche Ophthalmologische Gesellschaft 2026 in Berlin. The session will conclude with an expert panel on the future of the GA treatment algorithm and retinal specialist referral pathways. See the full list of PRIMA sessions at DOG 2026 in the link in the comments.
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All of our patients until now have had age-related macular degeneration (AMD). I'm excited that we've implanted our first Stargardt's patient, the first of several new indications we are now bringing to the clinic. Our PRIMalia study is enrolling in Sydney!
Science Corporation
@ScienceCorp_Sep 24
Blind Stargardt patient reads letter again in PRIMA by Science clinical trial. Stargardt disease destroys central vision. There is no treatment that brings it back. This clinical trial patient was diagnosed with Stargardt disease and became legally blind – he could no longer read or recognize faces. He's now part of the clinical trial testing Science's PRIMA implant (approved in Europe for geographic atrophy) in patients with Stargardt disease and retinitis pigmentosa. During his first rehabilitation session after surgery, he saw a letter again.
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for as much as they care about seemingly everything else, i totally fail to understand why the FDA hasn't acted against these guys yet. is misrepresenting statistics to patients for marketing just legal now?
Kian Sadeghi
@KianSadeghi5Sep 18
AI is rapidly getting smarter. Now, humanity can too. Today, @nucleusgenomics is announcing Vitruvian, our newest set of genetic optimization models. Vitruvian’s intelligence model can optimize embryo DNA for 14 IQ points — nearly a standard deviation. The models were trained on 1,000,000+ people, validated across 40,000+ siblings, and used more than 7 million genetic markers. In Superintelligence, Nick Bostrom proposed genetic optimization as a key way for humanity to keep pace with rapidly advancing AI. Bostrom’s vision is no longer theoretical. Genetic optimization, like AI, has followed a scaling law: as datasets have grown, so have model capabilities. This trend will continue. Parents across the world now have the choice to substantially increase their child’s intelligence. And the next generation can choose to do the same. AI is no longer the only intelligence that will compound. Humanity can now direct its own evolution.
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at best this is a clinical decision support tool that surely needs approval right? at which point someone will ask about pleiotropy and the fact that a spread is not a gain?
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outrageous
SFGATE
@SFGateSep 17
Bay Area man loses historic compound after decades of building disputes sfgate.com/bayarea/article/l…
Bay Area man loses historic compound after decades of building disputes

ALT Bay Area man loses historic compound after decades of building disputes

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Max Hodak retweeted
Zach Coelius
@zachcoeliusSep 17
An incredible example of the tyranny of the California permit dystopia. A man builds art on his own property and the state steals his land from him. Where miles away drug dealers murder a thousand people a year and nothing happens.
SFGATE
@SFGateSep 17
Bay Area man loses historic compound after decades of building disputes sfgate.com/bayarea/article/l…
Bay Area man loses historic compound after decades of building disputes

ALT Bay Area man loses historic compound after decades of building disputes

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Our 2026 summer interns, in their own words and their own edit. We were lucky to have them!
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I grew up in Manhattan and was 12 on 9/11/2001. Someone was randomly picked up by their parents during class, quickly followed by four or five other kids soon after. Eventually school was cancelled and I was picked up too; I forget by who, but it wasn't my mom, as she was busy leaving the WTC area (not the towers) and walking uptown along the Hudson. We had no information what was happening. As we were getting to our building on the UWS an F-15 flew overhead. For the next few years I was obsessed with foreign policy and national security. I didn't end up going into the military or government, but I really thought I would for a while. We said Never Forget, and we didn't.
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a few months later
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a few years later
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